JP2024523453A5 - - Google Patents
Info
- Publication number
- JP2024523453A5 JP2024523453A5 JP2023578817A JP2023578817A JP2024523453A5 JP 2024523453 A5 JP2024523453 A5 JP 2024523453A5 JP 2023578817 A JP2023578817 A JP 2023578817A JP 2023578817 A JP2023578817 A JP 2023578817A JP 2024523453 A5 JP2024523453 A5 JP 2024523453A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyldiyl
- peg
- pep
- heterocyclyldiyl
- immunocomplex
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163215100P | 2021-06-25 | 2021-06-25 | |
| US63/215,100 | 2021-06-25 | ||
| PCT/US2022/034865 WO2022272039A1 (en) | 2021-06-25 | 2022-06-24 | Bis-benzimidazole sting agonist immunoconjugates, and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024523453A JP2024523453A (ja) | 2024-06-28 |
| JP2024523453A5 true JP2024523453A5 (cg-RX-API-DMAC7.html) | 2025-06-16 |
Family
ID=82850579
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023578817A Pending JP2024523453A (ja) | 2021-06-25 | 2022-06-24 | ビス－ベンゾイミダゾールｓｔｉｎｇアゴニスト免疫複合体及びその使用 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20250057967A2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP4359007A1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2024523453A (cg-RX-API-DMAC7.html) |
| KR (1) | KR20240027018A (cg-RX-API-DMAC7.html) |
| CN (1) | CN117794583A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2022300383A1 (cg-RX-API-DMAC7.html) |
| CA (1) | CA3222082A1 (cg-RX-API-DMAC7.html) |
| IL (1) | IL309278A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2022272039A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024137619A1 (en) * | 2022-12-20 | 2024-06-27 | Bolt Biotherapeutics, Inc. | Anti-claudin, bis-benzimid azole sting agonist immunoconjugates, and uses thereof |
| WO2024174863A1 (zh) * | 2023-02-22 | 2024-08-29 | 深圳众格生物科技有限公司 | Sting激动剂及其制备方法和医药用途 |
| WO2025029832A2 (en) | 2023-07-31 | 2025-02-06 | Sutro Biopharma, Inc. | Sting agonist compounds and conjugates |
| CN117771206B (zh) * | 2023-08-02 | 2024-05-28 | 首都医科大学附属北京儿童医院 | Sting激动剂仿生纳米递送系统及其制备方法和应用 |
| WO2025233676A1 (en) * | 2024-05-08 | 2025-11-13 | Ligachem Biosciences Inc. | Compositions and methods related to a combination therapy of sting agonists and immune checkpoint inhibitors |
| WO2025233679A1 (en) * | 2024-05-08 | 2025-11-13 | Ligachem Biosciences Inc. | Compositions and methods related to a combination therapy of sting agonists and antibody drug conjugates |
| US20260053942A1 (en) | 2024-05-30 | 2026-02-26 | Astellas Pharama Inc. | Sting agonist immunostimulatory antibody drug conjugates |
| WO2026055185A1 (en) * | 2024-09-04 | 2026-03-12 | Bolt Biotherapeutics, Inc. | Sting agonist immunoconjugates and uses thereof |
| WO2026078593A1 (en) | 2024-10-08 | 2026-04-16 | Sun Pharma Advanced Research Company Limited | Sting agonists and antibody drug conjugates thereof |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT3440076T (pt) * | 2016-04-07 | 2022-07-29 | Glaxosmithkline Ip Dev Ltd | Amidas heterocíclicas úteis como modeladores de proteína |
| AR113224A1 (es) * | 2017-04-28 | 2020-02-19 | Novartis Ag | Conjugados de anticuerpo que comprenden un agonista de sting |
| CA3077337A1 (en) * | 2017-10-05 | 2019-04-11 | Glaxosmithkline Intellectual Property Development Limited | Modulators of stimulator of interferon genes (sting) |
| AU2018344902B2 (en) * | 2017-10-05 | 2021-06-03 | Glaxosmithkline Intellectual Property Development Limited | Modulators of stimulator of interferon genes (STING) useful in treating HIV |
| EP3848054B1 (en) * | 2018-09-06 | 2025-01-29 | Daiichi Sankyo Company, Limited | Antibody-drug conjugates of cyclic dinucleotide derivatives |
| WO2020092617A1 (en) * | 2018-10-31 | 2020-05-07 | Novartis Ag | Dc-sign antibody conjugates comprising sting agonists |
| WO2020214858A1 (en) * | 2019-04-17 | 2020-10-22 | Avidea Technologies, Inc. | Compositions and methods of manufacturing star polymers for ligand display and/or drug delivery |
| IL287938B2 (en) * | 2019-05-10 | 2025-07-01 | Takeda Pharmaceuticals Co | Antibody-drug conjugates |
| US20200390899A1 (en) * | 2019-06-13 | 2020-12-17 | Bolt Biotherapeutics, Inc. | Aminobenzazepine compounds, immunoconjugates, and uses thereof |
| CA3147890A1 (en) * | 2019-07-19 | 2021-01-28 | Immunesensor Therapeutics, Inc. | Antibody-sting agonist conjugates and their use in immunotherapy |
| IL296901A (en) * | 2020-04-02 | 2022-12-01 | Mersana Therapeutics Inc | Antibody-drug conjugates comprising sting agonists |
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2022
- 2022-06-24 CA CA3222082A patent/CA3222082A1/en active Pending
- 2022-06-24 EP EP22753804.8A patent/EP4359007A1/en active Pending
- 2022-06-24 WO PCT/US2022/034865 patent/WO2022272039A1/en not_active Ceased
- 2022-06-24 JP JP2023578817A patent/JP2024523453A/ja active Pending
- 2022-06-24 US US18/573,094 patent/US20250057967A2/en active Pending
- 2022-06-24 CN CN202280053551.7A patent/CN117794583A/zh active Pending
- 2022-06-24 KR KR1020247002332A patent/KR20240027018A/ko active Pending
- 2022-06-24 AU AU2022300383A patent/AU2022300383A1/en active Pending
- 2022-06-24 IL IL309278A patent/IL309278A/en unknown