JP2024522783A5 - - Google Patents

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Publication number
JP2024522783A5
JP2024522783A5 JP2023577845A JP2023577845A JP2024522783A5 JP 2024522783 A5 JP2024522783 A5 JP 2024522783A5 JP 2023577845 A JP2023577845 A JP 2023577845A JP 2023577845 A JP2023577845 A JP 2023577845A JP 2024522783 A5 JP2024522783 A5 JP 2024522783A5
Authority
JP
Japan
Prior art keywords
optionally substituted
prodrug
pharmaceutical product
alkyl
product according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023577845A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024522783A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/033654 external-priority patent/WO2022266237A1/en
Publication of JP2024522783A publication Critical patent/JP2024522783A/ja
Publication of JP2024522783A5 publication Critical patent/JP2024522783A5/ja
Pending legal-status Critical Current

Links

JP2023577845A 2021-06-18 2022-06-15 不均衡なヌクレオチドプールによって引き起こされたミトコンドリア疾患を治療するためのデオキシヌクレオシドのプロドラッグ Pending JP2024522783A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163212468P 2021-06-18 2021-06-18
US63/212,468 2021-06-18
PCT/US2022/033654 WO2022266237A1 (en) 2021-06-18 2022-06-15 Prodrugs of deoxynucleosides for treatment of mitochondrial diseases caused by unbalanced nucleotide pools

Publications (2)

Publication Number Publication Date
JP2024522783A JP2024522783A (ja) 2024-06-21
JP2024522783A5 true JP2024522783A5 (https=) 2025-06-24

Family

ID=84526701

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023577845A Pending JP2024522783A (ja) 2021-06-18 2022-06-15 不均衡なヌクレオチドプールによって引き起こされたミトコンドリア疾患を治療するためのデオキシヌクレオシドのプロドラッグ

Country Status (9)

Country Link
US (2) US20230000890A1 (https=)
EP (1) EP4355336A4 (https=)
JP (1) JP2024522783A (https=)
CN (1) CN117500510A (https=)
AU (1) AU2022291783A1 (https=)
CA (1) CA3222484A1 (https=)
IL (1) IL309421A (https=)
MX (1) MX2023014944A (https=)
WO (1) WO2022266237A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022204555A1 (en) * 2021-03-26 2022-09-29 Zogenix Mds, Inc. Aqueous solutions containing purines and pyrimidines and uses thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10292996B2 (en) * 2015-03-26 2019-05-21 The Trustees Of Columbia University In The City Of New York Deoxyribonucleoside monophospate bypass therapy for mitochondrial DNA depletion syndrome
LT3505174T (lt) * 2015-06-17 2020-09-10 The Trustees Of Columbia University In The City Of New York Deoksinukleozidų terapija, skirta gydyti ligas, kurias sukelia nesubalansuoti nukleotidų kiekiai, įskaitant mitochondrinės dnr išsekimo sindromus
CA3005444A1 (en) * 2015-11-16 2017-05-26 Ichorion Therapeutics, Inc. Nucleic acid prodrugs
CA3096264A1 (en) * 2018-04-12 2019-10-17 Modis Therapeutics Inc. Prodrugs of deoxynucleosides for treatment of diseases cased by unbalanced nucleotide pools

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