JP2024522769A - 自己免疫性血液学的疾患を治療する方法 - Google Patents

自己免疫性血液学的疾患を治療する方法 Download PDF

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Publication number
JP2024522769A
JP2024522769A JP2023577713A JP2023577713A JP2024522769A JP 2024522769 A JP2024522769 A JP 2024522769A JP 2023577713 A JP2023577713 A JP 2023577713A JP 2023577713 A JP2023577713 A JP 2023577713A JP 2024522769 A JP2024522769 A JP 2024522769A
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iptacopan
subject
patient
weeks
hydrochloride
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JP2024522769A5 (https=
Inventor
ウェレンシーク，アンナ スベーニャ シューバルト
ユンゲ，グイド
ホルブロ，トーマス
チャウラ，ラーガバ
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ノバルティス アーゲー
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2023577713A 2021-06-18 2022-06-17 自己免疫性血液学的疾患を治療する方法 Pending JP2024522769A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163212465P 2021-06-18 2021-06-18
US63/212,465 2021-06-18
PCT/IB2022/055639 WO2022264101A1 (en) 2021-06-18 2022-06-17 Method of treating an autoimmune hematological disorder

Publications (2)

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JP2024522769A true JP2024522769A (ja) 2024-06-21
JP2024522769A5 JP2024522769A5 (https=) 2025-06-04

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JP2023577713A Pending JP2024522769A (ja) 2021-06-18 2022-06-17 自己免疫性血液学的疾患を治療する方法

Country Status (5)

Country Link
US (1) US20240277689A1 (https=)
EP (1) EP4355329A1 (https=)
JP (1) JP2024522769A (https=)
CN (1) CN117500500A (https=)
WO (1) WO2022264101A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2021414253B2 (en) * 2020-12-30 2024-05-16 Shanghai Fosun Pharmaceutical Industrial Development Co., Ltd. Series of piperidine-substituted benzoic acid compounds, and use thereof
US20250161347A1 (en) 2023-11-22 2025-05-22 Flagship Pioneering Innovations Vii, Llc Methods and compositions for treating non-alcoholic fatty liver disease
WO2025148628A1 (zh) * 2024-01-10 2025-07-17 河北以岭医药研究院有限公司 哌啶基吲哚衍生物及其制备方法和应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JO3425B1 (ar) 2013-07-15 2019-10-20 Novartis Ag مشتقات البابيريدينيل-اندول واستخدامها كعامل متمم لمثبطات b
CN120208923A (zh) 2020-05-18 2025-06-27 诺华股份有限公司 Lnp023的结晶形式

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Publication number Publication date
CN117500500A (zh) 2024-02-02
WO2022264101A1 (en) 2022-12-22
US20240277689A1 (en) 2024-08-22
EP4355329A1 (en) 2024-04-24

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