JP2024522083A - ナノポアを使用して分子を検出する多重方法 - Google Patents

ナノポアを使用して分子を検出する多重方法 Download PDF

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Publication number
JP2024522083A
JP2024522083A JP2023571924A JP2023571924A JP2024522083A JP 2024522083 A JP2024522083 A JP 2024522083A JP 2023571924 A JP2023571924 A JP 2023571924A JP 2023571924 A JP2023571924 A JP 2023571924A JP 2024522083 A JP2024522083 A JP 2024522083A
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Japan
Prior art keywords
molecule
carrier
region
identifier
molecular binding
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Pending
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JP2023571924A
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English (en)
Japanese (ja)
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JP2024522083A5 (https=
Inventor
ジョン ヘロン，アンドリュー
アレクサンダー グティエレズ，リチャード
エデル，ジョシュア
イワノフ，アレクサンダー
コッホ，キャロライン
シュエ，リアン
ライリー－オドネル，ベネディクト
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Ip2ipo Innovations Ltd
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Imperial College Innovations Ltd
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Application filed by Imperial College Innovations Ltd filed Critical Imperial College Innovations Ltd
Publication of JP2024522083A publication Critical patent/JP2024522083A/ja
Publication of JP2024522083A5 publication Critical patent/JP2024522083A5/ja
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6825—Nucleic acid detection involving sensors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • G—PHYSICS
    • G11—INFORMATION STORAGE
    • G11C—STATIC STORES
    • G11C13/00—Digital stores characterised by the use of storage elements not covered by groups G11C11/00, G11C23/00, or G11C25/00
    • G11C13/0002—Digital stores characterised by the use of storage elements not covered by groups G11C11/00, G11C23/00, or G11C25/00 using resistive RAM [RRAM] elements
    • G11C13/0009—RRAM elements whose operation depends upon chemical change
    • G11C13/0014—RRAM elements whose operation depends upon chemical change comprising cells based on organic memory material
    • G11C13/0019—RRAM elements whose operation depends upon chemical change comprising cells based on organic memory material comprising bio-molecules

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2023571924A 2021-05-19 2022-05-19 ナノポアを使用して分子を検出する多重方法 Pending JP2024522083A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB2107192.3 2021-05-19
GBGB2107192.3A GB202107192D0 (en) 2021-05-19 2021-05-19 Method
PCT/GB2022/051268 WO2022243691A1 (en) 2021-05-19 2022-05-19 Multiplex methods of detecting molecules using nanopores

Publications (2)

Publication Number Publication Date
JP2024522083A true JP2024522083A (ja) 2024-06-11
JP2024522083A5 JP2024522083A5 (https=) 2025-05-20

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ID=76550727

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JP2023571924A Pending JP2024522083A (ja) 2021-05-19 2022-05-19 ナノポアを使用して分子を検出する多重方法

Country Status (8)

Country Link
US (1) US20250283153A1 (https=)
EP (1) EP4341427A1 (https=)
JP (1) JP2024522083A (https=)
CN (1) CN118103523A (https=)
AU (1) AU2022276473A1 (https=)
CA (1) CA3218861A1 (https=)
GB (1) GB202107192D0 (https=)
WO (1) WO2022243691A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB202301095D0 (en) 2023-01-25 2023-03-08 Oxford Nanopore Tech Plc Calibration of a nanopore array device

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KR101939420B1 (ko) 2011-02-11 2019-01-16 옥스포드 나노포어 테크놀로지즈 리미티드 돌연변이체 세공
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GB201120910D0 (en) 2011-12-06 2012-01-18 Cambridge Entpr Ltd Nanopore functionality control
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CN117947149A (zh) 2013-10-18 2024-04-30 牛津纳米孔科技公开有限公司 经修饰的酶
SI3074534T1 (sl) * 2013-11-26 2019-08-30 Illumina, Inc. Postopki določanja zaporedja polinukleotidov
WO2015150786A1 (en) 2014-04-04 2015-10-08 Oxford Nanopore Technologies Limited Method for characterising a double stranded nucleic acid using a nano-pore and anchor molecules at both ends of said nucleic acid
GB201417712D0 (en) 2014-10-07 2014-11-19 Oxford Nanopore Tech Ltd Method
WO2016009180A1 (en) 2014-07-14 2016-01-21 Isis Innovation Limited Measurement of analytes with membrane channel molecules, and bilayer arrays
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US10480026B2 (en) * 2014-10-17 2019-11-19 Oxford Nanopore Technologies Ltd. Method for nanopore RNA characterisation
CN116200476A (zh) 2016-03-02 2023-06-02 牛津纳米孔科技公开有限公司 靶分析物测定方法、突变CsgG单体及其构筑体、及聚核苷酸和寡聚孔
GB201612458D0 (en) 2016-07-14 2016-08-31 Howorka Stefan And Pugh Genevieve Membrane spanning DNA nanopores for molecular transport
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GB201907244D0 (en) 2019-05-22 2019-07-03 Oxford Nanopore Tech Ltd Method

Also Published As

Publication number Publication date
US20250283153A1 (en) 2025-09-11
AU2022276473A1 (en) 2023-11-30
CA3218861A1 (en) 2022-11-24
CN118103523A (zh) 2024-05-28
EP4341427A1 (en) 2024-03-27
GB202107192D0 (en) 2021-06-30
AU2022276473A9 (en) 2023-12-07
WO2022243691A1 (en) 2022-11-24

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