JP2024522073A - ナノポアプロテオミクス - Google Patents

ナノポアプロテオミクス Download PDF

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Publication number
JP2024522073A
JP2024522073A JP2023571762A JP2023571762A JP2024522073A JP 2024522073 A JP2024522073 A JP 2024522073A JP 2023571762 A JP2023571762 A JP 2023571762A JP 2023571762 A JP2023571762 A JP 2023571762A JP 2024522073 A JP2024522073 A JP 2024522073A
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JP
Japan
Prior art keywords
nanopore
pore
prot
swiss
analyte
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Pending
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JP2023571762A
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English (en)
Japanese (ja)
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JP2024522073A5 (https=
Inventor
レオナルドゥス ルドルフス ルカス、フローリアン
コルスティアン アブラハム フェルスロート、ロードリック
マッリア、ジョヴァンニ
Original Assignee
レイクスユニフェルシテイト フローニンゲン
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Publication of JP2024522073A publication Critical patent/JP2024522073A/ja
Publication of JP2024522073A5 publication Critical patent/JP2024522073A5/ja
Pending legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43595Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from coelenteratae, e.g. medusae
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/01Preparation of mutants without inserting foreign genetic material therein; Screening processes therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • G01N33/54373Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6818Sequencing of polypeptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Plant Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
JP2023571762A 2021-05-18 2022-05-18 ナノポアプロテオミクス Pending JP2024522073A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP21174437 2021-05-18
EP21174437.0 2021-05-18
PCT/NL2022/050266 WO2022245209A2 (en) 2021-05-18 2022-05-18 Nanopore proteomics

Publications (2)

Publication Number Publication Date
JP2024522073A true JP2024522073A (ja) 2024-06-11
JP2024522073A5 JP2024522073A5 (https=) 2025-08-07

Family

ID=76011701

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023571762A Pending JP2024522073A (ja) 2021-05-18 2022-05-18 ナノポアプロテオミクス

Country Status (10)

Country Link
US (1) US20240159768A1 (https=)
EP (1) EP4341278A2 (https=)
JP (1) JP2024522073A (https=)
KR (1) KR20240010007A (https=)
CN (1) CN117957243A (https=)
AU (1) AU2022277010A1 (https=)
CA (1) CA3219470A1 (https=)
IL (1) IL308635A (https=)
MX (1) MX2023013655A (https=)
WO (1) WO2022245209A2 (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB202112235D0 (en) * 2021-08-26 2021-10-13 Oxford Nanopore Tech Ltd Nanopore
EP4412624A4 (en) 2021-10-04 2025-08-20 Neuvivo Inc TREATMENT METHODS FOR ALS PATIENTS
KR20250116014A (ko) 2022-10-28 2025-07-31 리엑스유니버시테이트 그로닝겐 나노기공-기반 단백질 분석
CN120476132A (zh) * 2022-12-29 2025-08-12 深圳华大生命科学研究院 新型孔蛋白bcp34、其突变体及其应用
GB202305524D0 (en) * 2023-04-14 2023-05-31 Oxford Nanopore Tech Plc Novel pore monomers and pores
CN120917151A (zh) * 2023-04-28 2025-11-07 清华大学 一种被修饰的多肽、多肽复合物、多肽混合物及控制多肽移位速度或表征多肽的系统和方法
WO2025003492A1 (en) * 2023-06-30 2025-01-02 Ecole Polytechnique Federale De Lausanne (Epfl) Uses of aerolysin nanopores
EP4491190A1 (en) * 2023-07-14 2025-01-15 Fundación Imdea Alimentación Small proteins for use as senolytic and senomorphic agents
WO2025138302A1 (zh) * 2023-12-30 2025-07-03 深圳华大生命科学研究院 蛋白测序文库的构建方法及蛋白质的测序方法
WO2025229321A1 (en) * 2024-04-30 2025-11-06 Portal Biotech Ltd. Nanopores and uses thereof for analysis of analytes
WO2026052817A1 (en) * 2024-09-06 2026-03-12 Oxford Nanopore Technologies Plc Method

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0820927D0 (en) * 2008-11-14 2008-12-24 Isis Innovation Method
WO2020055246A1 (en) * 2018-09-11 2020-03-19 Rijksuniversiteit Groningen Biological nanopores having tunable pore diameters and uses thereof as analytical tools
CN112500459B (zh) * 2020-02-29 2023-04-07 南京大学 Aerolysin突变纳米孔及其在分子生物检测方面的应用
CN112480204A (zh) * 2020-04-13 2021-03-12 南京大学 一种采用Aerolysin纳米孔道的蛋白质/多肽测序方法

Also Published As

Publication number Publication date
WO2022245209A2 (en) 2022-11-24
IL308635A (en) 2024-01-01
KR20240010007A (ko) 2024-01-23
US20240159768A1 (en) 2024-05-16
CA3219470A1 (en) 2022-11-24
EP4341278A2 (en) 2024-03-27
WO2022245209A3 (en) 2022-12-29
AU2022277010A1 (en) 2023-12-14
MX2023013655A (es) 2024-02-06
CN117957243A (zh) 2024-04-30

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