JP2024521806A5 - - Google Patents

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Publication number
JP2024521806A5
JP2024521806A5 JP2023573060A JP2023573060A JP2024521806A5 JP 2024521806 A5 JP2024521806 A5 JP 2024521806A5 JP 2023573060 A JP2023573060 A JP 2023573060A JP 2023573060 A JP2023573060 A JP 2023573060A JP 2024521806 A5 JP2024521806 A5 JP 2024521806A5
Authority
JP
Japan
Prior art keywords
sequence
nuclease
cas nuclease
variant
cas
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023573060A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024521806A (ja
Filing date
Publication date
Priority claimed from GBGB2107671.6A external-priority patent/GB202107671D0/en
Application filed filed Critical
Priority claimed from PCT/EP2022/064307 external-priority patent/WO2022248607A2/en
Publication of JP2024521806A publication Critical patent/JP2024521806A/ja
Publication of JP2024521806A5 publication Critical patent/JP2024521806A5/ja
Pending legal-status Critical Current

Links

JP2023573060A 2021-05-25 2022-05-25 合成Ｃａｓタンパク質 Pending JP2024521806A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
EP21382474 2021-05-25
EP21382474.1 2021-05-25
GBGB2107671.6A GB202107671D0 (en) 2021-05-28 2021-05-28 Synthetic cas proteins
GB2107671.6 2021-05-28
EP22165690 2022-03-30
EP22165690.3 2022-03-30
PCT/EP2022/064307 WO2022248607A2 (en) 2021-05-25 2022-05-25 Synthetic cas proteins

Publications (2)

Publication Number Publication Date
JP2024521806A JP2024521806A (ja) 2024-06-04
JP2024521806A5 true JP2024521806A5 (https=) 2025-06-02

Family

ID=82319633

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023573060A Pending JP2024521806A (ja) 2021-05-25 2022-05-25 合成Ｃａｓタンパク質

Country Status (4)

Country Link
US (1) US20240240165A1 (https=)
EP (1) EP4347808A2 (https=)
JP (1) JP2024521806A (https=)
WO (1) WO2022248607A2 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2024236558A1 (en) 2023-03-15 2025-10-09 Renagade Therapeutics Management Inc. Delivery of gene editing systems and methods of use thereof
AU2024335327A1 (en) 2023-09-01 2026-03-26 Renagade Therapeutics Management Inc. Gene editing systems, compositions, and methods for treatment of vexas syndrome
WO2025061765A1 (en) 2023-09-19 2025-03-27 Asociación Centro De Investigación Cooperativa En Biociencias-Cic Biogune Synthetic cas proteins
WO2025174765A1 (en) 2024-02-12 2025-08-21 Renagade Therapeutics Management Inc. Lipid nanoparticles comprising coding rna molecules for use in gene editing and as vaccines and therapeutic agents

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL3145934T3 (pl) * 2014-05-19 2021-08-16 Pfizer Inc. Podstawione związki 6,8-dioksabicyklo[3.2.1]oktano-2,3-diolu jako środki kierujące do ASGPR
US20150376586A1 (en) * 2014-06-25 2015-12-31 Caribou Biosciences, Inc. RNA Modification to Engineer Cas9 Activity
JP7044373B2 (ja) 2015-07-15 2022-03-30 ラトガース，ザ ステート ユニバーシティ オブ ニュージャージー ヌクレアーゼ非依存的な標的化遺伝子編集プラットフォームおよびその用途
IL310721B2 (en) * 2015-10-23 2025-11-01 Harvard College Nucleobase editors and uses thereof
WO2017096041A1 (en) * 2015-12-02 2017-06-08 The Regents Of The University Of California Compositions and methods for modifying a target nucleic acid
US11427837B2 (en) * 2016-01-12 2022-08-30 The Regents Of The University Of California Compositions and methods for enhanced genome editing
US10351803B2 (en) * 2016-02-01 2019-07-16 Ecolab Usa Inc. Solid laundry detergent for restaurant soils
CN110214183A (zh) * 2016-08-03 2019-09-06 哈佛大学的校长及成员们 腺苷核碱基编辑器及其用途
KR102622411B1 (ko) * 2016-10-14 2024-01-10 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 핵염기 에디터의 aav 전달
EP3676376B1 (en) * 2017-08-30 2025-01-15 President and Fellows of Harvard College High efficiency base editors comprising gam
AU2018393050A1 (en) * 2017-12-21 2020-06-18 Bayer Healthcare Llc Materials and methods for treatment of Usher Syndrome Type 2A
US12060586B2 (en) * 2018-02-15 2024-08-13 The Broad Institute, Inc. Cell data recorders and uses thereof
WO2019165168A1 (en) * 2018-02-23 2019-08-29 Pioneer Hi-Bred International, Inc. Novel cas9 orthologs
WO2020086908A1 (en) * 2018-10-24 2020-04-30 The Broad Institute, Inc. Constructs for improved hdr-dependent genomic editing
WO2021084533A1 (en) * 2019-10-28 2021-05-06 Targetgene Biotechnologies Ltd Pam-reduced and pam-abolished cas derivatives compositions and uses thereof in genetic modulation
US20230002746A1 (en) * 2019-10-31 2023-01-05 Inari Agriculture Technology, Inc. Base-editing systems

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