JP2024521364A - 組換えワクシニアウイルスにより免疫応答を誘導するための方法および組成物 - Google Patents

組換えワクシニアウイルスにより免疫応答を誘導するための方法および組成物 Download PDF

Info

Publication number
JP2024521364A
JP2024521364A JP2023574560A JP2023574560A JP2024521364A JP 2024521364 A JP2024521364 A JP 2024521364A JP 2023574560 A JP2023574560 A JP 2023574560A JP 2023574560 A JP2023574560 A JP 2023574560A JP 2024521364 A JP2024521364 A JP 2024521364A
Authority
JP
Japan
Prior art keywords
virus
antigen
recombinant vaccinia
vaccinia virus
evs
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023574560A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024521364A5 (https=
Inventor
エム. ワード ブライアン
モンチセリ ステファニー
ブリック ピーター
Original Assignee
ユニバーシティー オブ ロチェスター
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ユニバーシティー オブ ロチェスター filed Critical ユニバーシティー オブ ロチェスター
Publication of JP2024521364A publication Critical patent/JP2024521364A/ja
Publication of JP2024521364A5 publication Critical patent/JP2024521364A5/ja
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/215Coronaviridae, e.g. avian infectious bronchitis virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5254Virus avirulent or attenuated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5256Virus expressing foreign proteins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Mycology (AREA)
  • Plant Pathology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pulmonology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2023574560A 2021-06-04 2022-05-20 組換えワクシニアウイルスにより免疫応答を誘導するための方法および組成物 Pending JP2024521364A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163202295P 2021-06-04 2021-06-04
US63/202,295 2021-06-04
PCT/US2022/030297 WO2022256188A1 (en) 2021-06-04 2022-05-20 Methods and composition for inducing an immune response by a recombinant vaccinia virus

Publications (2)

Publication Number Publication Date
JP2024521364A true JP2024521364A (ja) 2024-05-31
JP2024521364A5 JP2024521364A5 (https=) 2025-05-09

Family

ID=82116005

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023574560A Pending JP2024521364A (ja) 2021-06-04 2022-05-20 組換えワクシニアウイルスにより免疫応答を誘導するための方法および組成物

Country Status (4)

Country Link
US (1) US20240240205A1 (https=)
EP (1) EP4346895A1 (https=)
JP (1) JP2024521364A (https=)
WO (1) WO2022256188A1 (https=)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050196755A1 (en) * 2000-11-17 2005-09-08 Maurice Zauderer In vitro methods of producing and identifying immunoglobulin molecules in eukaryotic cells

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
"Bryk P. J., Investigation of the Roles of Vaccinia Virus Protein F13 and its Molluscum Contagiosum V", THESIS FOR THE DEGREE OF DOCTOR OF PHILOSOPHY, JPN6026010602, 2018, pages 72 - 108, ISSN: 0005818211 *
HUM VACCIN IMMUNOTHER, 2012 JUL 1, VOL. 8(7), PP. 961-970, vol. vol. 8(7), JPN6026010604, 1 July 2012 (2012-07-01), pages 961 - 970, ISSN: 0005818213 *
J VIROL, vol. vol. 87(12), JPN6026010605, 17 April 2013 (2013-04-17), pages 6955 - 6974, ISSN: 0005818214 *
J VIROL, vol. vol. 94(20), JPN6026010603, 29 September 2020 (2020-09-29), pages 01496 - 20, ISSN: 0005818212 *

Also Published As

Publication number Publication date
US20240240205A1 (en) 2024-07-18
EP4346895A1 (en) 2024-04-10
WO2022256188A1 (en) 2022-12-08

Similar Documents

Publication Publication Date Title
US10842864B2 (en) MVA vaccine for delivery of a UL128 complex and preventing CMV infection
US12584146B2 (en) Synthetic modified vaccinia Ankara (SMVA) based coronavirus vaccines
US8535687B2 (en) Smallpox DNA vaccine and the antigens therein that elicit an immune response
US20190247491A1 (en) Methods for inducing an immune response against human immunodeficiency virus infection in subjects undergoing antiretroviral treatment
CN106999571A (zh) 诱导针对人免疫缺陷病毒感染的保护性免疫性的方法和组合物
AU2022235527B2 (en) Single high dose of mva induces a protective immune response in neonates and infants
US20190083620A1 (en) Methods for inducing an immune response against human immunodeficiency virus infection in subjects undergoing antiretroviral treatment
US20250161435A1 (en) Multivalent kaposi sarcoma-associated herpesvirus-like particles and uses thereof
US20240240205A1 (en) Methods and composition for inducing an immune response by a recombinnat vaccinia virus
Yu et al. One time intranasal vaccination with a modified vaccinia Tiantan strain MVTTZCI protects animals against pathogenic viral challenge
KR20250029119A (ko) 엡스타인-바-바이러스 백신
EA052954B1 (ru) Вакцина против вируса эпштейна-барр
EP4108257A1 (en) Mva-based vaccine against covid-19 expressing a prefusion-stabilized sars-cov-2 s protein
TW202334434A (zh) 對抗嚴重急性呼吸道症候群冠狀病毒2型之基於痘病毒的疫苗及使用該疫苗的方法
Zhou et al. CircRNA Based Bi-Antigen Vaccines Against Mpox Virus Induces Potent and Durable Protection in Mice

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20231211

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20250424

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20250424

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20260317

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20260319