JP2024520756A5 - - Google Patents

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Publication number
JP2024520756A5
JP2024520756A5 JP2023575397A JP2023575397A JP2024520756A5 JP 2024520756 A5 JP2024520756 A5 JP 2024520756A5 JP 2023575397 A JP2023575397 A JP 2023575397A JP 2023575397 A JP2023575397 A JP 2023575397A JP 2024520756 A5 JP2024520756 A5 JP 2024520756A5
Authority
JP
Japan
Prior art keywords
peg
pharmaceutical composition
composition according
polypeptide
lnp
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023575397A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024520756A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/032510 external-priority patent/WO2022261101A1/en
Publication of JP2024520756A publication Critical patent/JP2024520756A/ja
Publication of JP2024520756A5 publication Critical patent/JP2024520756A5/ja
Pending legal-status Critical Current

Links

JP2023575397A 2021-06-07 2022-06-07 ApoE及びApoB修飾脂質ナノ粒子組成物及びその使用 Pending JP2024520756A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163197881P 2021-06-07 2021-06-07
US63/197,881 2021-06-07
PCT/US2022/032510 WO2022261101A1 (en) 2021-06-07 2022-06-07 Apoe and apob modified lipid nanoparticle compositions and uses thereof

Publications (2)

Publication Number Publication Date
JP2024520756A JP2024520756A (ja) 2024-05-24
JP2024520756A5 true JP2024520756A5 (enExample) 2025-06-17

Family

ID=84426303

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023575397A Pending JP2024520756A (ja) 2021-06-07 2022-06-07 ApoE及びApoB修飾脂質ナノ粒子組成物及びその使用

Country Status (9)

Country Link
US (1) US20240299580A1 (enExample)
EP (1) EP4351533A4 (enExample)
JP (1) JP2024520756A (enExample)
KR (1) KR20240019244A (enExample)
CN (1) CN117897143A (enExample)
AU (1) AU2022288618A1 (enExample)
CA (1) CA3221454A1 (enExample)
IL (1) IL308928A (enExample)
WO (1) WO2022261101A1 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024119103A1 (en) 2022-12-01 2024-06-06 Generation Bio Co. Lipid nanoparticles comprising nucleic acids and lipid-anchored polymers
EP4626400A1 (en) 2022-12-01 2025-10-08 Generation Bio Co. Novel polyglycerol-conjugated lipids and lipid nanoparticle compositions comprising the same
WO2024119074A1 (en) 2022-12-01 2024-06-06 Generation Bio Co. Stealth lipid nanoparticle compositions for cell targeting
AU2023406303A1 (en) 2022-12-01 2025-05-29 Generation Bio Co. Lipid nanoparticles comprising nucleic acids, ionizable lipids, sterols, lipid anchored polymers and helper lipids, their uses
US20240226133A1 (en) * 2023-01-09 2024-07-11 Claudia Chimisso Dos Santos Microrna-based particle for the treatment of dysregulated immune response
WO2024200820A1 (en) 2023-03-30 2024-10-03 Ose Immunotherapeutics Method of synthesis of targeted lipid nanoparticle and uses thereof
EP4687991A1 (en) 2023-03-30 2026-02-11 Ose Immunotherapeutics Lipid-based nanoparticle targeted at activated immune cells for the expression of immune cell enhancing molecule and use thereof
WO2024226779A1 (en) * 2023-04-26 2024-10-31 Saliogen Therapeutics, Inc. Lipid nanoparticle (lnp) formulations
IT202300015291A1 (it) * 2023-07-20 2025-01-20 Fond Riccardo Terzi E Silvio Albini Sistema di rilascio comprendente nanoparticelle lipidiche o polimeriche comprendenti ormoni tiroidei
WO2025052180A2 (en) 2023-09-07 2025-03-13 Axelyf ehf. Lipids and lipid nanoparticles
WO2025230906A1 (en) * 2024-04-29 2025-11-06 Saliogen Therapeutics, Inc. Lipid nanoparticle (lnp) formulations
WO2026003582A2 (en) 2024-06-27 2026-01-02 Axelyf ehf. Lipids and lipid nanoparticles
CN118453517B (zh) * 2024-07-15 2024-10-08 杭州珞米医疗科技有限公司 一种靶向结合ldlr的组合物及其应用
WO2026052871A1 (en) * 2024-09-09 2026-03-12 Re3B Therapeutics Ug (I.G.) Serum-protein coated fusogenic lipid particles for targeted drug delivery
WO2026064512A1 (en) 2024-09-18 2026-03-26 Generation Bio Co. Polyglycerol-conjugated lipids and lipid nanoparticle compositions comprising the same

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1796712A4 (en) * 2004-09-07 2009-11-11 Kos Life Sciences Inc METHOD AND COMPOSITIONS FOR TREATING HYPERCHOLESTEROLEMIA
AR069328A1 (es) * 2007-11-15 2010-01-13 Alcon Mfg Ltd Liberacion de rna interferente corto o sirna, intermediada por receptor de lipoproteina de baja densidad
WO2019040516A1 (en) * 2017-08-22 2019-02-28 Rubius Therapeutics, Inc. METHODS AND COMPOSITIONS OF LIPID NANOPARTICLES FOR THE PRODUCTION OF MODIFIED ERYTHROID CELLS
EP3934700A4 (en) * 2019-03-06 2022-12-14 Generation Bio Co. NON-ACTIVE LIPID NANOPARTICLES WITH CAPSID-FREE, NON-VIRAL DNA
WO2021046265A1 (en) * 2019-09-06 2021-03-11 Generation Bio Co. Lipid nanoparticle compositions comprising closed-ended dna and cleavable lipids and methods of use thereof
WO2022076547A1 (en) * 2020-10-07 2022-04-14 Precision Biosciences, Inc. Lipid nanoparticle compositions

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