JP2024520756A5 - - Google Patents
Info
- Publication number
- JP2024520756A5 JP2024520756A5 JP2023575397A JP2023575397A JP2024520756A5 JP 2024520756 A5 JP2024520756 A5 JP 2024520756A5 JP 2023575397 A JP2023575397 A JP 2023575397A JP 2023575397 A JP2023575397 A JP 2023575397A JP 2024520756 A5 JP2024520756 A5 JP 2024520756A5
- Authority
- JP
- Japan
- Prior art keywords
- peg
- pharmaceutical composition
- composition according
- polypeptide
- lnp
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163197881P | 2021-06-07 | 2021-06-07 | |
| US63/197,881 | 2021-06-07 | ||
| PCT/US2022/032510 WO2022261101A1 (en) | 2021-06-07 | 2022-06-07 | Apoe and apob modified lipid nanoparticle compositions and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024520756A JP2024520756A (ja) | 2024-05-24 |
| JP2024520756A5 true JP2024520756A5 (enExample) | 2025-06-17 |
Family
ID=84426303
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023575397A Pending JP2024520756A (ja) | 2021-06-07 | 2022-06-07 | ApoE及びApoB修飾脂質ナノ粒子組成物及びその使用 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20240299580A1 (enExample) |
| EP (1) | EP4351533A4 (enExample) |
| JP (1) | JP2024520756A (enExample) |
| KR (1) | KR20240019244A (enExample) |
| CN (1) | CN117897143A (enExample) |
| AU (1) | AU2022288618A1 (enExample) |
| CA (1) | CA3221454A1 (enExample) |
| IL (1) | IL308928A (enExample) |
| WO (1) | WO2022261101A1 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024119103A1 (en) | 2022-12-01 | 2024-06-06 | Generation Bio Co. | Lipid nanoparticles comprising nucleic acids and lipid-anchored polymers |
| EP4626400A1 (en) | 2022-12-01 | 2025-10-08 | Generation Bio Co. | Novel polyglycerol-conjugated lipids and lipid nanoparticle compositions comprising the same |
| WO2024119074A1 (en) | 2022-12-01 | 2024-06-06 | Generation Bio Co. | Stealth lipid nanoparticle compositions for cell targeting |
| AU2023406303A1 (en) | 2022-12-01 | 2025-05-29 | Generation Bio Co. | Lipid nanoparticles comprising nucleic acids, ionizable lipids, sterols, lipid anchored polymers and helper lipids, their uses |
| US20240226133A1 (en) * | 2023-01-09 | 2024-07-11 | Claudia Chimisso Dos Santos | Microrna-based particle for the treatment of dysregulated immune response |
| WO2024200820A1 (en) | 2023-03-30 | 2024-10-03 | Ose Immunotherapeutics | Method of synthesis of targeted lipid nanoparticle and uses thereof |
| EP4687991A1 (en) | 2023-03-30 | 2026-02-11 | Ose Immunotherapeutics | Lipid-based nanoparticle targeted at activated immune cells for the expression of immune cell enhancing molecule and use thereof |
| WO2024226779A1 (en) * | 2023-04-26 | 2024-10-31 | Saliogen Therapeutics, Inc. | Lipid nanoparticle (lnp) formulations |
| IT202300015291A1 (it) * | 2023-07-20 | 2025-01-20 | Fond Riccardo Terzi E Silvio Albini | Sistema di rilascio comprendente nanoparticelle lipidiche o polimeriche comprendenti ormoni tiroidei |
| WO2025052180A2 (en) | 2023-09-07 | 2025-03-13 | Axelyf ehf. | Lipids and lipid nanoparticles |
| WO2025230906A1 (en) * | 2024-04-29 | 2025-11-06 | Saliogen Therapeutics, Inc. | Lipid nanoparticle (lnp) formulations |
| WO2026003582A2 (en) | 2024-06-27 | 2026-01-02 | Axelyf ehf. | Lipids and lipid nanoparticles |
| CN118453517B (zh) * | 2024-07-15 | 2024-10-08 | 杭州珞米医疗科技有限公司 | 一种靶向结合ldlr的组合物及其应用 |
| WO2026052871A1 (en) * | 2024-09-09 | 2026-03-12 | Re3B Therapeutics Ug (I.G.) | Serum-protein coated fusogenic lipid particles for targeted drug delivery |
| WO2026064512A1 (en) | 2024-09-18 | 2026-03-26 | Generation Bio Co. | Polyglycerol-conjugated lipids and lipid nanoparticle compositions comprising the same |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1796712A4 (en) * | 2004-09-07 | 2009-11-11 | Kos Life Sciences Inc | METHOD AND COMPOSITIONS FOR TREATING HYPERCHOLESTEROLEMIA |
| AR069328A1 (es) * | 2007-11-15 | 2010-01-13 | Alcon Mfg Ltd | Liberacion de rna interferente corto o sirna, intermediada por receptor de lipoproteina de baja densidad |
| WO2019040516A1 (en) * | 2017-08-22 | 2019-02-28 | Rubius Therapeutics, Inc. | METHODS AND COMPOSITIONS OF LIPID NANOPARTICLES FOR THE PRODUCTION OF MODIFIED ERYTHROID CELLS |
| EP3934700A4 (en) * | 2019-03-06 | 2022-12-14 | Generation Bio Co. | NON-ACTIVE LIPID NANOPARTICLES WITH CAPSID-FREE, NON-VIRAL DNA |
| WO2021046265A1 (en) * | 2019-09-06 | 2021-03-11 | Generation Bio Co. | Lipid nanoparticle compositions comprising closed-ended dna and cleavable lipids and methods of use thereof |
| WO2022076547A1 (en) * | 2020-10-07 | 2022-04-14 | Precision Biosciences, Inc. | Lipid nanoparticle compositions |
-
2022
- 2022-06-07 CA CA3221454A patent/CA3221454A1/en active Pending
- 2022-06-07 KR KR1020247000414A patent/KR20240019244A/ko active Pending
- 2022-06-07 CN CN202280053409.2A patent/CN117897143A/zh active Pending
- 2022-06-07 JP JP2023575397A patent/JP2024520756A/ja active Pending
- 2022-06-07 WO PCT/US2022/032510 patent/WO2022261101A1/en not_active Ceased
- 2022-06-07 IL IL308928A patent/IL308928A/en unknown
- 2022-06-07 AU AU2022288618A patent/AU2022288618A1/en active Pending
- 2022-06-07 US US18/567,412 patent/US20240299580A1/en active Pending
- 2022-06-07 EP EP22820897.1A patent/EP4351533A4/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2024520756A5 (enExample) | ||
| Sun et al. | Structure and function of cationic and ionizable lipids for nucleic acid delivery | |
| US12252470B2 (en) | Lipids and nanoparticle compositions thereof | |
| JP2023534043A5 (enExample) | ||
| US20230320993A1 (en) | Methods for encapsulating polynucleotides into reduced sizes of lipid nanoparticles and novel formulation thereof | |
| AU2020423601B2 (en) | Lipid nanoparticles for in-vivo drug delivery, and uses thereof | |
| US20220370357A1 (en) | Ionizable lipids and nanoparticle compositions thereof | |
| US12263228B2 (en) | Lipids and compositions thereof | |
| JP2024520756A (ja) | ApoE及びApoB修飾脂質ナノ粒子組成物及びその使用 | |
| US20240293574A1 (en) | Cationic lipids and compositions thereof | |
| JP2024517644A5 (enExample) | ||
| JP2024522692A5 (enExample) | ||
| US20230181764A1 (en) | Novel lipids and nanoparticle compositions thereof | |
| JP2024529343A5 (enExample) | ||
| JP2025541727A (ja) | 新規のポリグリセロールコンジュゲート脂質及びそれを含む脂質ナノ粒子組成物 | |
| Koynova et al. | Recent patents in cationic lipid carriers for delivery of nucleic acids | |
| Sorgi et al. | Drug delivery applications | |
| KR20250158420A (ko) | 신규 이온화지질 및 이를 포함하는 지질나노입자 | |
| NICOLAUª et al. | ªCBR Laboratories and Harvard Medical School, Boston, MA 02135, USA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA and CPMCRI, San Francisco, CA 94115, USA | |
| BHATTACHARYAT et al. | Cationic liposome-DNA complexes in |