JP2024520497A - Ｃｍ－ｔｍａバイオマーカーを検出するための方法 - Google Patents

Ｃｍ－ｔｍａバイオマーカーを検出するための方法 Download PDF

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Publication number
JP2024520497A
JP2024520497A JP2023573141A JP2023573141A JP2024520497A JP 2024520497 A JP2024520497 A JP 2024520497A JP 2023573141 A JP2023573141 A JP 2023573141A JP 2023573141 A JP2023573141 A JP 2023573141A JP 2024520497 A JP2024520497 A JP 2024520497A
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Prior art keywords
creatinine
sc5b9
cystatin
complement
plasma
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Japanese (ja)
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JP2024520497A5 (https=
Inventor
トビン ジェイ． キャメット，
スーザン ファース マックナイト，
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アレクシオン ファーマシューティカルズ， インコーポレイテッド
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Publication of JP2024520497A publication Critical patent/JP2024520497A/ja
Publication of JP2024520497A5 publication Critical patent/JP2024520497A5/ja
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4716—Complement proteins, e.g. anaphylatoxin, C3a, C5a
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/22—Haematology
    • G01N2800/226—Thrombotic disorders, i.e. thrombo-embolism irrespective of location/organ involved, e.g. renal vein thrombosis, venous thrombosis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2023573141A 2021-05-28 2022-05-26 Ｃｍ－ｔｍａバイオマーカーを検出するための方法 Pending JP2024520497A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202163194704P 2021-05-28 2021-05-28
US63/194,704 2021-05-28
US202163272033P 2021-10-26 2021-10-26
US63/272,033 2021-10-26
PCT/US2022/031062 WO2022251446A1 (en) 2021-05-28 2022-05-26 Methods for detecting cm-tma biomarkers

Publications (2)

Publication Number Publication Date
JP2024520497A true JP2024520497A (ja) 2024-05-24
JP2024520497A5 JP2024520497A5 (https=) 2025-05-22

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ID=82214465

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JP2023573141A Pending JP2024520497A (ja) 2021-05-28 2022-05-26 Ｃｍ－ｔｍａバイオマーカーを検出するための方法

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Country Link
US (1) US20250199013A1 (https=)
EP (1) EP4348263A1 (https=)
JP (1) JP2024520497A (https=)
CA (1) CA3220629A1 (https=)
WO (1) WO2022251446A1 (https=)

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WO2019227102A1 (en) * 2018-05-25 2019-11-28 Achillion Pharmaceuticals, Inc. Complement alternative pathway-associated nephropathy biomarkers
JP2021501134A (ja) * 2017-10-26 2021-01-14 アレクシオン ファーマシューティカルズ， インコーポレイテッド 発作性夜間ヘモグロビン尿症（ＰＮＨ）および非典型溶血性尿毒症症候群（ａＨＵＳ）の処置のための抗Ｃ５抗体の投薬量および投与

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JP2021501134A (ja) * 2017-10-26 2021-01-14 アレクシオン ファーマシューティカルズ， インコーポレイテッド 発作性夜間ヘモグロビン尿症（ＰＮＨ）および非典型溶血性尿毒症症候群（ａＨＵＳ）の処置のための抗Ｃ５抗体の投薬量および投与
WO2019227102A1 (en) * 2018-05-25 2019-11-28 Achillion Pharmaceuticals, Inc. Complement alternative pathway-associated nephropathy biomarkers

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WO2022251446A1 (en) 2022-12-01
US20250199013A1 (en) 2025-06-19
EP4348263A1 (en) 2024-04-10
CA3220629A1 (en) 2022-12-01

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