|
US12479834B2
(en)
|
2019-11-29 |
2025-11-25 |
Taiho Pharmaceutical Co., Ltd. |
Phenol compound or salt thereof
|
|
EP4161926A4
(en)
*
|
2020-06-03 |
2024-06-19 |
Yumanity Therapeutics, Inc. |
PYRIDOPYRIMIDINES AND THEIR METHODS OF USE
|
|
WO2023018812A1
(en)
*
|
2021-08-10 |
2023-02-16 |
Amgen Inc. |
Heterocyclic compounds and methods of use
|
|
TW202328124A
(zh)
*
|
2021-08-18 |
2023-07-16 |
大陸商北京加科思新藥研發有限公司 |
1,4-氧雜氮雜環庚烷衍生物及其用途
|
|
WO2023061294A1
(zh)
*
|
2021-10-13 |
2023-04-20 |
再鼎医药(上海)有限公司 |
含氮杂环类衍生物调节剂、其制备方法及应用
|
|
TW202334138A
(zh)
|
2021-11-05 |
2023-09-01 |
美商新領域醫藥公司 |
癌症治療方法
|
|
JP2024543879A
(ja)
*
|
2021-11-24 |
2024-11-26 |
メルク・シャープ・アンド・ドーム・エルエルシー |
Ｋｒａｓ変異型タンパク質の小分子阻害剤
|
|
EP4444289A4
(en)
*
|
2021-12-08 |
2025-12-17 |
Kineta Inc |
PYRIDOPYRIMIDINS AND METHODS FOR THEIR USE
|
|
CN118556063A
(zh)
*
|
2022-01-21 |
2024-08-27 |
上海湃隆生物科技有限公司 |
杂环类化合物、药物组合物及其应用
|
|
CN118900838A
(zh)
*
|
2022-03-24 |
2024-11-05 |
百济神州有限公司 |
杂环化合物、其组合物及其治疗方法
|
|
WO2023213269A1
(en)
*
|
2022-05-06 |
2023-11-09 |
Zai Lab (Shanghai) Co., Ltd. |
Amide-substituted heterocyclic compounds as kras g12d modulators and uses thereof
|
|
WO2023246777A1
(en)
*
|
2022-06-20 |
2023-12-28 |
Jacobio Pharmaceuticals Co., Ltd. |
K-ras mutant protein inhibitors
|
|
WO2024008068A1
(en)
*
|
2022-07-04 |
2024-01-11 |
Jacobio Pharmaceuticals Co., Ltd. |
K-ras mutant protein inhibitors
|
|
WO2024012519A1
(zh)
*
|
2022-07-13 |
2024-01-18 |
北京华森英诺生物科技有限公司 |
Pan-kras抑制剂
|
|
CN117624170A
(zh)
*
|
2022-08-24 |
2024-03-01 |
泰励生物科技（上海）有限公司 |
具有抗kras突变肿瘤活性的化合物
|
|
CN120077051A
(zh)
*
|
2022-10-21 |
2025-05-30 |
苏州亚盛药业有限公司 |
Kras抑制剂
|
|
WO2024112654A1
(en)
|
2022-11-21 |
2024-05-30 |
Treeline Biosciences, Inc. |
Spirocyclic dihydropyranopyrimidine kras inhibitors
|
|
CN118165011A
(zh)
*
|
2022-12-08 |
2024-06-11 |
润佳(上海)医药工程有限公司 |
Kras抑制剂及其用途
|
|
WO2024125600A1
(zh)
*
|
2022-12-14 |
2024-06-20 |
上海科州药物研发有限公司 |
作为kras抑制剂的杂环化合物，及其制备和治疗用途
|
|
WO2024138206A1
(en)
*
|
2022-12-23 |
2024-06-27 |
Frontier Medicines Corporation |
Fluoropyridopyrimidine and fluoroquinazoline derivaties and methods of use thereof
|
|
WO2024209339A1
(en)
*
|
2023-04-05 |
2024-10-10 |
Pfizer Inc. |
Pyrido[4,3-d]pyrimidine compounds
|
|
KR20260015208A
(ko)
|
2023-05-12 |
2026-02-02 |
재즈 파마슈티칼즈 아일랜드 리미티드 |
암 치료에 유용한 g12d 돌연변이체 kras의 조절제로서 피라졸로[4,3-f]퀴나졸린 유도체
|
|
CN119101070A
(zh)
*
|
2023-06-07 |
2024-12-10 |
上海璎黎药业有限公司 |
一种含氮杂环化合物、其药物组合物及应用
|
|
IL326136A
(en)
|
2023-08-07 |
2026-03-01 |
Revolution Medicines Inc |
RMC-6291 for use in the treatment of a disease or disorder associated with the RAS protein
|
|
AU2024323424A1
(en)
|
2023-08-17 |
2026-03-05 |
Treeline Biosciences, Inc. |
Spirocyclic dihydropyranopyrimidine kras inhibitors
|
|
AU2024337913A1
(en)
|
2023-09-08 |
2026-03-26 |
Gilead Sciences, Inc. |
Pyrimidine-containing polycyclic derivatives as kras g12d modulating compounds
|
|
TW202528315A
(zh)
|
2023-09-21 |
2025-07-16 |
美商樹線生物科學公司 |
螺環二氫哌喃并吡啶ＫＲａｓ抑制劑
|
|
US20250154171A1
(en)
|
2023-10-12 |
2025-05-15 |
Revolution Medicines, Inc. |
Ras inhibitors
|
|
WO2025085748A1
(en)
|
2023-10-20 |
2025-04-24 |
Merck Sharp & Dohme Llc |
Small molecule inhibitors of kras proteins
|
|
WO2025163494A1
(en)
|
2024-01-29 |
2025-08-07 |
Jazz Pharmaceuticals Ireland Ltd. |
Condensed azines for the treatment of cancer
|
|
WO2025171296A1
(en)
|
2024-02-09 |
2025-08-14 |
Revolution Medicines, Inc. |
Ras inhibitors
|
|
WO2025235740A1
(en)
*
|
2024-05-08 |
2025-11-13 |
Merck Sharp & Dohme Llc |
Small molecule inhibitors of kras proteins
|
|
WO2025240847A1
(en)
|
2024-05-17 |
2025-11-20 |
Revolution Medicines, Inc. |
Ras inhibitors
|
|
WO2025245127A1
(en)
|
2024-05-21 |
2025-11-27 |
Treeline Biosciences, Inc. |
Spirocyclic dihydropyranopyrimidine kras inhibitors
|
|
US20250375445A1
(en)
|
2024-06-07 |
2025-12-11 |
Revolution Medicines, Inc. |
Methods of treating a ras protein-related disease or disorder
|
|
WO2025265060A1
(en)
|
2024-06-21 |
2025-12-26 |
Revolution Medicines, Inc. |
Therapeutic compositions and methods for managing treatment-related effects
|
|
WO2026006747A1
(en)
|
2024-06-28 |
2026-01-02 |
Revolution Medicines, Inc. |
Ras inhibitors
|
|
WO2026015796A1
(en)
|
2024-07-12 |
2026-01-15 |
Revolution Medicines, Inc. |
Methods of treating a ras related disease or disorder
|
|
WO2026015825A1
(en)
|
2024-07-12 |
2026-01-15 |
Revolution Medicines, Inc. |
Use of ras inhibitor for treating pancreatic cancer
|
|
WO2026015790A1
(en)
|
2024-07-12 |
2026-01-15 |
Revolution Medicines, Inc. |
Methods of treating a ras related disease or disorder
|
|
WO2026015801A1
(en)
|
2024-07-12 |
2026-01-15 |
Revolution Medicines, Inc. |
Methods of treating a ras related disease or disorder
|
|
WO2026050446A1
(en)
|
2024-08-29 |
2026-03-05 |
Revolution Medicines, Inc. |
Ras inhibitors
|
|
WO2026072904A2
(en)
|
2024-09-26 |
2026-04-02 |
Revolution Medicines, Inc. |
Compositions and methods for treating lung cancer
|