JP2024517935A - Ｃｙｐ３ａ阻害剤及びアザシチジンと組み合わせて骨髄異形成症候群の処置に使用されるベネトクラクス投与レジメン - Google Patents

Ｃｙｐ３ａ阻害剤及びアザシチジンと組み合わせて骨髄異形成症候群の処置に使用されるベネトクラクス投与レジメン Download PDF

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JP2024517935A
JP2024517935A JP2023569873A JP2023569873A JP2024517935A JP 2024517935 A JP2024517935 A JP 2024517935A JP 2023569873 A JP2023569873 A JP 2023569873A JP 2023569873 A JP2023569873 A JP 2023569873A JP 2024517935 A JP2024517935 A JP 2024517935A
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venetoclax
ritonavir
cyp3a inhibitor
combination
daily dose
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JP2024517935A5 (enExample
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ヘイスリップ，ジョン
カイ，スティーブ・エイチ
サーレム，アハメド
ジャア，ジウホン
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AbbVie Inc
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AbbVie Inc
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    • A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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JP2023569873A 2021-05-11 2022-05-10 Ｃｙｐ３ａ阻害剤及びアザシチジンと組み合わせて骨髄異形成症候群の処置に使用されるベネトクラクス投与レジメン Pending JP2024517935A (ja)

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US202163201743P 2021-05-11 2021-05-11
US63/201,743 2021-05-11
PCT/US2022/028434 WO2022240788A1 (en) 2021-05-11 2022-05-10 Venetoclax dosing regimens for use in treating myelodysplastic syndromes in combination with a cyp3a inhibitor and azacitidine

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JP2024517935A true JP2024517935A (ja) 2024-04-23
JP2024517935A5 JP2024517935A5 (enExample) 2025-05-16

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US (1) US20220370481A1 (enExample)
EP (1) EP4337208A4 (enExample)
JP (1) JP2024517935A (enExample)
KR (1) KR20240006660A (enExample)
CN (1) CN117651556A (enExample)
AU (1) AU2022273615A1 (enExample)
BR (1) BR112023023638A2 (enExample)
CA (1) CA3219761A1 (enExample)
IL (1) IL308318A (enExample)
MX (1) MX2023013361A (enExample)
WO (1) WO2022240788A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20220315555A1 (en) 2009-05-26 2022-10-06 Abbvie Inc. Apoptosis inducing agents for the treatment of cancer and immune and autoimmune diseases
US20240350524A1 (en) * 2023-04-06 2024-10-24 Abbvie Inc. Dosing regimens for use in preventing relapse of acute myeloid leukemia following allogeneic hematopoietic stem cell transplantation with venetoclax in combination with azacitidine

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3258941A4 (en) * 2015-02-17 2018-09-26 Cantex Pharmaceuticals, Inc. Treatment of cancers and hematopoietic stem cell disorders privileged by cxcl12-cxcr4 interaction
CN109789143A (zh) * 2016-07-01 2019-05-21 G1治疗公司 基于嘧啶的抗增殖剂
WO2020257671A1 (en) * 2019-06-20 2020-12-24 Celgene Corporation Azacitidine in combination with venetoclax, gilteritinib, midostaurin or other compounds for treating leukemia or myelodysplastic syndrome

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
AMERICAN JOURNAL OF HEMATOLOGY, vol. 93, no. 3, JPN6026016044, 2018, pages 401 - 407, ISSN: 0005849636 *
BLOOD, vol. Vol.134, Supplement 1, JPN6026016043, 2019, pages 2640, ISSN: 0005849635 *
BLOOD, vol. Vol.134, Supplement 1, No.568, JPN6026016046, 2019, ISSN: 0005849638 *
BLOOD, vol. Vol.136, Supplement 1, JPN6026016042, 2020, pages 55 - 57, ISSN: 0005849634 *
JOURNAL OF CLINICAL ONCOLOGY, vol. Vol.36, No.15_Suppl, JPN6026016045, 2018, pages 7082, ISSN: 0005849637 *

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KR20240006660A (ko) 2024-01-15
AU2022273615A1 (en) 2023-11-23
EP4337208A1 (en) 2024-03-20
US20220370481A1 (en) 2022-11-24
MX2023013361A (es) 2023-11-27
BR112023023638A2 (pt) 2024-01-30
IL308318A (en) 2024-01-01
CA3219761A1 (en) 2022-11-17
WO2022240788A1 (en) 2022-11-17
EP4337208A4 (en) 2025-03-12
CN117651556A (zh) 2024-03-05

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