JP2024517641A5 - - Google Patents

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Publication number
JP2024517641A5
JP2024517641A5 JP2023564111A JP2023564111A JP2024517641A5 JP 2024517641 A5 JP2024517641 A5 JP 2024517641A5 JP 2023564111 A JP2023564111 A JP 2023564111A JP 2023564111 A JP2023564111 A JP 2023564111A JP 2024517641 A5 JP2024517641 A5 JP 2024517641A5
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JP
Japan
Prior art keywords
cells
subject
cancer
human
tgf
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Pending
Application number
JP2023564111A
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English (en)
Japanese (ja)
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JP2024517641A (ja
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Priority claimed from PCT/US2022/025612 external-priority patent/WO2022226101A1/en
Publication of JP2024517641A publication Critical patent/JP2024517641A/ja
Publication of JP2024517641A5 publication Critical patent/JP2024517641A5/ja
Pending legal-status Critical Current

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JP2023564111A 2021-04-20 2022-04-20 免疫細胞の遺伝子改変および治療的使用のための方法および組成物 Pending JP2024517641A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163177053P 2021-04-20 2021-04-20
US63/177,053 2021-04-20
PCT/US2022/025612 WO2022226101A1 (en) 2021-04-20 2022-04-20 Methods and compositions for genetic modification and therapeutic use of immune cells

Publications (2)

Publication Number Publication Date
JP2024517641A JP2024517641A (ja) 2024-04-23
JP2024517641A5 true JP2024517641A5 (https=) 2025-05-16

Family

ID=83723226

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023564111A Pending JP2024517641A (ja) 2021-04-20 2022-04-20 免疫細胞の遺伝子改変および治療的使用のための方法および組成物

Country Status (5)

Country Link
US (1) US20240197782A1 (https=)
EP (1) EP4326291A4 (https=)
JP (1) JP2024517641A (https=)
CN (1) CN117915928A (https=)
WO (1) WO2022226101A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7698577B2 (ja) * 2018-10-18 2025-06-25 ボード オブ リージェンツ ザ ユニヴァーシティ オブ テキサス システム 組織常在メモリー様t細胞を生成するための方法及びその使用
CN118871586A (zh) * 2022-01-26 2024-10-29 奥泽生物疗法公司 用于改善关节功能的基因编辑

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0955378A1 (en) * 1998-04-06 1999-11-10 Bente Lomholt Langdahl Method and kit for detecting a sequence variation in the human TGF-beta 1 gene
WO2000001410A1 (en) * 1998-07-06 2000-01-13 Beth Israel Deaconess Medical Center Methods of inhibiting proliferative diseases by inhibiting tgf-beta mediated angiogenesis
KR101286053B1 (ko) * 2011-06-13 2013-07-19 연세대학교 산학협력단 TGF-β1 발현을 억제하는 shRNA
EP3610266A4 (en) * 2017-04-12 2021-04-21 Massachusetts Eye and Ear Infirmary TUMOR SIGNATURE OF METASTASIS, COMPOSITIONS OF SUBSTANCES AND USES THEREOF
WO2019089884A2 (en) * 2017-11-01 2019-05-09 Editas Medicine, Inc. Methods, compositions and components for crispr-cas9 editing of tgfbr2 in t cells for immunotherapy
JP2021525518A (ja) * 2018-05-31 2021-09-27 ワシントン・ユニバーシティWashington University 細胞をゲノム編集及び活性化するための方法
CN110904045A (zh) * 2018-09-17 2020-03-24 中国科学院动物研究所 经修饰的t细胞、其制备方法及用途
AU2020288829A1 (en) * 2019-06-04 2021-12-02 Nkarta, Inc. Combinations of engineered natural killer cells and engineered T cells for immunotherapy
US20250127811A1 (en) * 2021-01-28 2025-04-24 Precision Biosciences, Inc. Modulation of tgf beta signaling in genetically-modified eukaryotic cells

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