JP2024517355A - 血管内皮炎の治療において使用するための中間分子量ヘパリン - Google Patents
血管内皮炎の治療において使用するための中間分子量ヘパリン Download PDFInfo
- Publication number
- JP2024517355A JP2024517355A JP2023570373A JP2023570373A JP2024517355A JP 2024517355 A JP2024517355 A JP 2024517355A JP 2023570373 A JP2023570373 A JP 2023570373A JP 2023570373 A JP2023570373 A JP 2023570373A JP 2024517355 A JP2024517355 A JP 2024517355A
- Authority
- JP
- Japan
- Prior art keywords
- molecular weight
- weight heparin
- intermediate molecular
- vwf
- use according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/727—Heparin; Heparan
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Dermatology (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB2106972.9A GB202106972D0 (en) | 2021-05-14 | 2021-05-14 | Medium molecular weight heparin |
| GB2106972.9 | 2021-05-14 | ||
| PCT/EP2022/063222 WO2022238587A1 (en) | 2021-05-14 | 2022-05-16 | Medium molecular weight heparin for use in the treatment of endotheliopathy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024517355A true JP2024517355A (ja) | 2024-04-19 |
| JP2024517355A5 JP2024517355A5 (enExample) | 2025-05-26 |
Family
ID=76550734
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023570373A Pending JP2024517355A (ja) | 2021-05-14 | 2022-05-16 | 血管内皮炎の治療において使用するための中間分子量ヘパリン |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20240245718A1 (enExample) |
| EP (1) | EP4337225A1 (enExample) |
| JP (1) | JP2024517355A (enExample) |
| CN (1) | CN117915923A (enExample) |
| AU (1) | AU2022273186A1 (enExample) |
| CA (1) | CA3219993A1 (enExample) |
| GB (1) | GB202106972D0 (enExample) |
| WO (1) | WO2022238587A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2024381335A1 (en) | 2023-11-17 | 2026-05-21 | Glycos Biomedical Ltd. | Medium molecular weight heparin |
| GB202407360D0 (en) | 2024-05-23 | 2024-07-10 | Glycos Biomedical Ltd | Functionalised medium molecular weight heparin |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2020504185A (ja) * | 2017-01-11 | 2020-02-06 | フィタゴラス ベー.ヴェー.Fytagoras B.V. | 中分子量ヘパリン |
| WO2020231830A1 (en) * | 2019-05-16 | 2020-11-19 | Exthera Medical Corporation | Method for modulating endothelial glycocalyx structure |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HK1045532A1 (zh) * | 1999-06-30 | 2002-11-29 | Hamilton Civic Hospitals Research Development, Inc. | 抑制与凝结有关凝结因子的肝素成份 |
| JP2021155334A (ja) * | 2018-05-01 | 2021-10-07 | 学校法人近畿大学 | 中分子ヘパリンまたは中分子ヘパリンのアミノ酸誘導体を含む医薬組成物 |
| WO2022016098A1 (en) * | 2020-07-17 | 2022-01-20 | Xostem Ip, Inc. | Compositions and methods for treatment of inflammatory and thromboinflammatory disorders using modified exosomes |
-
2021
- 2021-05-14 GB GBGB2106972.9A patent/GB202106972D0/en not_active Ceased
-
2022
- 2022-05-16 CA CA3219993A patent/CA3219993A1/en active Pending
- 2022-05-16 WO PCT/EP2022/063222 patent/WO2022238587A1/en not_active Ceased
- 2022-05-16 AU AU2022273186A patent/AU2022273186A1/en active Pending
- 2022-05-16 JP JP2023570373A patent/JP2024517355A/ja active Pending
- 2022-05-16 EP EP22729556.5A patent/EP4337225A1/en active Pending
- 2022-05-16 CN CN202280045684.XA patent/CN117915923A/zh active Pending
- 2022-05-16 US US18/290,533 patent/US20240245718A1/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2020504185A (ja) * | 2017-01-11 | 2020-02-06 | フィタゴラス ベー.ヴェー.Fytagoras B.V. | 中分子量ヘパリン |
| WO2020231830A1 (en) * | 2019-05-16 | 2020-11-19 | Exthera Medical Corporation | Method for modulating endothelial glycocalyx structure |
Non-Patent Citations (2)
| Title |
|---|
| [ONLINE], vol. [検索日 2026.04.14], JPN6026016052, 2020, pages 2, ISSN: 0005849644 * |
| CIRCULATION, vol. 93, no. 5, JPN6026016051, 1996, pages 992 - 999, ISSN: 0005849643 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN117915923A (zh) | 2024-04-19 |
| US20240245718A1 (en) | 2024-07-25 |
| EP4337225A1 (en) | 2024-03-20 |
| GB202106972D0 (en) | 2021-06-30 |
| WO2022238587A1 (en) | 2022-11-17 |
| CA3219993A1 (en) | 2022-11-17 |
| AU2022273186A1 (en) | 2024-01-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| van Lier et al. | Experimental human endotoxemia as a model of systemic inflammation | |
| Best et al. | The efficacy and safety of short-and long-term dual antiplatelet therapy in patients with mild or moderate chronic kidney disease: results from the Clopidogrel for the Reduction of Events During Observation (CREDO) trial | |
| KR20140053881A (ko) | 모세관 누출의 예방 및 치료를 위한 수술 동안 투여되는 프로스타시클린 및 그 유사체 | |
| JP2001506603A (ja) | 抗―Xa活性を有する化合物及び血小板凝集拮抗剤化合物を含有する製薬組成物 | |
| US20240245718A1 (en) | Medium molecular weight heparin for use in the treatment of endotheliopathy | |
| Topsakal et al. | Effects of chronic obstructive pulmonary disease on coronary atherosclerosis | |
| Fealy et al. | A pilot randomized controlled crossover study comparing regional heparinization to regional citrate anticoagulation for continuous venovenous hemofiltration | |
| Rikken et al. | Prepercutaneous coronary intervention Zalunfiban dose-response relationship to target vessel blood flow at initial angiogram in st-elevation myocardial infarction–A post hoc analysis of the cel-02 phase IIa study | |
| Jankowska-Sanetra et al. | Incidence and course of acute coronary syndrome cases after the first wave of the COVID-19 pandemic | |
| WO2024105271A1 (en) | Preparation of medium molecular weight heparin | |
| Lunetta et al. | Lowering of plasma viscosity by the oral administration of the glycosaminoglycan sulodexide in patients with peripheral vascular disease | |
| Ades et al. | Factor XI inhibitors: potential role in end-stage kidney disease | |
| HK40109661A (en) | Medium molecular weight heparin for use in the treatment of endotheliopathy | |
| Dixon et al. | Elevated pulmonary dead space and coagulation abnormalities suggest lung microvascular thrombosis in patients undergoing cardiac surgery | |
| Tsipis et al. | Novel oral anticoagulants in peripheral arterial and coronary artery disease | |
| Sharma et al. | Tranexamic acid leads to paradoxical coagulation changes during cardiac surgery: a pilot rotational thromboelastometry study | |
| JP2025537781A (ja) | 中間分子量ヘパリンの調製 | |
| Bendel et al. | Dabigatran: an oral direct thrombin inhibitor for use in atrial fibrillation | |
| WO2025106117A1 (en) | Medium molecular weight heparin | |
| Uğuz et al. | In vitro analysis of the effect of contrast agents on the antiaggregant effects of P2Y12 inhibitors | |
| WO2025245445A1 (en) | Functionalised medium molecular weight heparin | |
| Shi et al. | Effect of statins combined with PCSK9 inhibitors on the prognosis of patients with acute coronary syndromes after interventional therapy | |
| Armstrong et al. | Pharmacology of hemostasis and thrombosis | |
| Wang et al. | Stuck Between a Rock and a Hard Place: Anticoagulation in End-Stage Kidney Disease Patients With Atrial Fibrillation | |
| Ren et al. | A review of antiplatelet drugs, coronary artery diseases and cardiopulmonary bypass |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20250515 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20250515 |
|
| A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20260423 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20260428 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20260727 |