JP2024515936A5 - - Google Patents

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Publication number
JP2024515936A5
JP2024515936A5 JP2023556950A JP2023556950A JP2024515936A5 JP 2024515936 A5 JP2024515936 A5 JP 2024515936A5 JP 2023556950 A JP2023556950 A JP 2023556950A JP 2023556950 A JP2023556950 A JP 2023556950A JP 2024515936 A5 JP2024515936 A5 JP 2024515936A5
Authority
JP
Japan
Prior art keywords
ribonucleic acid
guide
sequence
manipulated
class
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023556950A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024515936A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/021004 external-priority patent/WO2022198080A1/en
Publication of JP2024515936A publication Critical patent/JP2024515936A/ja
Publication of JP2024515936A5 publication Critical patent/JP2024515936A5/ja
Pending legal-status Critical Current

Links

JP2023556950A 2021-03-19 2022-03-18 Cas酵素を用いたマルチプレックス編集 Pending JP2024515936A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US202163163510P 2021-03-19 2021-03-19
US63/163,510 2021-03-19
US202163186506P 2021-05-10 2021-05-10
US63/186,506 2021-05-10
US202163241916P 2021-09-08 2021-09-08
US63/241,916 2021-09-08
PCT/US2022/021004 WO2022198080A1 (en) 2021-03-19 2022-03-18 Multiplex editing with cas enzymes

Publications (2)

Publication Number Publication Date
JP2024515936A JP2024515936A (ja) 2024-04-11
JP2024515936A5 true JP2024515936A5 (https=) 2025-03-25

Family

ID=83321225

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023556950A Pending JP2024515936A (ja) 2021-03-19 2022-03-18 Cas酵素を用いたマルチプレックス編集

Country Status (9)

Country Link
US (1) US20250075233A1 (https=)
EP (1) EP4308699A4 (https=)
JP (1) JP2024515936A (https=)
KR (1) KR20230157387A (https=)
AU (1) AU2022237663A1 (https=)
BR (1) BR112023018948A2 (https=)
CA (1) CA3210361A1 (https=)
MX (1) MX2023010969A (https=)
WO (1) WO2022198080A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021178933A2 (en) 2020-03-06 2021-09-10 Metagenomi Ip Technologies, Llc Class ii, type v crispr systems
WO2021226363A1 (en) * 2020-05-08 2021-11-11 Metagenomi Ip Technologies, Llc Enzymes with ruvc domains
CA3205865A1 (en) * 2021-01-22 2022-07-28 Brian C. Thomas Novel engineered and chimeric nucleases
AU2022335499A1 (en) 2021-08-27 2024-02-22 Metagenomi Therapeutics, Inc. Enzymes with ruvc domains
AU2022396533A1 (en) 2021-11-24 2024-05-02 Metagenomi Therapeutics, Inc. Endonuclease systems
WO2024127370A1 (en) * 2022-12-16 2024-06-20 LifeEDIT Therapeutics, Inc. Guide rnas that target trac gene and methods of use

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003099215A2 (en) * 2002-05-20 2003-12-04 Pharmacia Corporation Antisense modulation of glucocorticoid receptor expression
US20150017136A1 (en) * 2013-07-15 2015-01-15 Cellectis Methods for engineering allogeneic and highly active t cell for immunotherapy
CA2985650A1 (en) * 2015-05-13 2016-11-17 Seattle Children's Hospital (dba Seattle Children's Research Institute) Enhancing endonuclease based gene editing in primary cells
EP3423580A1 (en) * 2016-03-04 2019-01-09 Editas Medicine, Inc. Crispr-cpf1-related methods, compositions and components for cancer immunotherapy
MX2019013514A (es) * 2017-05-12 2020-01-20 Crispr Therapeutics Ag Materiales y metodos para modificar celulas por ingenieria genetica y usos de los mismos en inmunooncologia.
EP3686275A4 (en) * 2017-09-18 2021-09-29 Edigene Inc. GENE EDITING LYMPHOCYTE T AND RELATED USE
EP3746554A1 (en) * 2018-01-30 2020-12-09 Editas Medicine, Inc. Systems and methods for modulating chromosomal rearrangements
US12275951B2 (en) * 2018-02-06 2025-04-15 Ohio State Innovation Foundation Engineered guide RNA and uses thereof
CA3089587A1 (en) * 2018-02-08 2019-08-15 Sangamo Therapeutics, Inc. Engineered target specific nucleases
CA3241703C (en) * 2019-02-14 2026-02-24 Metagenomi Therapeutics, Inc. Enzymes with ruvc domains
US10913941B2 (en) * 2019-02-14 2021-02-09 Metagenomi Ip Technologies, Llc Enzymes with RuvC domains
CN113825834A (zh) * 2019-03-11 2021-12-21 索伦托药业有限公司 使用rna引导的核酸内切酶进行dna构建体整合的改进工艺
GB201907733D0 (en) * 2019-05-31 2019-07-17 Governing Council Of The Univ Of Toronto Methods and compositions for multiplex gene editing

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