JP2024513950A - キャピラリー電気泳動におけるタンパク質分析のための天然蛍光検出 - Google Patents

キャピラリー電気泳動におけるタンパク質分析のための天然蛍光検出 Download PDF

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JP2024513950A
JP2024513950A JP2023562537A JP2023562537A JP2024513950A JP 2024513950 A JP2024513950 A JP 2024513950A JP 2023562537 A JP2023562537 A JP 2023562537A JP 2023562537 A JP2023562537 A JP 2023562537A JP 2024513950 A JP2024513950 A JP 2024513950A
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radiation
sample
light source
excitation
target protein
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JP2024513950A5 (https=
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スニール デリワラ，
ティンティン リー，
ヤガン リウ，
ジョン シルゼル，
ザイファン ジュー，
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ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44704—Details; Accessories
    • G01N27/44717—Arrangements for investigating the separated zones, e.g. localising zones
    • G01N27/44721—Arrangements for investigating the separated zones, e.g. localising zones by optical means
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G01N2030/8809—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
    • G01N2030/8813—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials
    • G01N2030/8831—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials involving peptides or proteins

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Optical Measuring Cells (AREA)
JP2023562537A 2021-04-14 2022-04-12 キャピラリー電気泳動におけるタンパク質分析のための天然蛍光検出 Pending JP2024513950A (ja)

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Application Number Priority Date Filing Date Title
US202163174897P 2021-04-14 2021-04-14
US63/174,897 2021-04-14
US202163292277P 2021-12-21 2021-12-21
US63/292,277 2021-12-21
PCT/IB2022/053442 WO2022219538A1 (en) 2021-04-14 2022-04-12 Native fluorescence detection for protein analysis in capillary electrophoresis

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JP2024513950A true JP2024513950A (ja) 2024-03-27
JP2024513950A5 JP2024513950A5 (https=) 2025-04-18

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US (1) US20240201131A1 (https=)
EP (1) EP4323761A1 (https=)
JP (1) JP2024513950A (https=)
WO (1) WO2022219538A1 (https=)

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH10104234A (ja) * 1996-09-26 1998-04-24 Hitachi Ltd 抗原抗体反応測定用抗体および装置
WO2005033687A1 (en) * 2003-01-17 2005-04-14 University Of Virginia Patent Foundation Method for microchip and capillary detection of proteins in the sub-ug/ml range
JP2005526969A (ja) * 2002-04-12 2005-09-08 アマシャム・バイオサイエンス・（エスブイ）・コーポレイション 多重キャピラリー電気泳動システム
JP2018528389A (ja) * 2015-05-12 2018-09-27 リジェネロン・ファーマシューティカルズ・インコーポレイテッド 多量体タンパク質の純度の決定
WO2019234544A1 (en) * 2018-06-04 2019-12-12 Dh Technologies Development Pte. Ltd. Lbmfi detector for fluorophore labeled analytes at the taylor cone in esi-ms
JP2020106412A (ja) * 2018-12-27 2020-07-09 パナソニックＩｐマネジメント株式会社 生体分子の検出方法及び肌状態の評価方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5268486A (en) * 1986-04-18 1993-12-07 Carnegie-Mellon Unversity Method for labeling and detecting materials employing arylsulfonate cyanine dyes

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH10104234A (ja) * 1996-09-26 1998-04-24 Hitachi Ltd 抗原抗体反応測定用抗体および装置
JP2005526969A (ja) * 2002-04-12 2005-09-08 アマシャム・バイオサイエンス・（エスブイ）・コーポレイション 多重キャピラリー電気泳動システム
WO2005033687A1 (en) * 2003-01-17 2005-04-14 University Of Virginia Patent Foundation Method for microchip and capillary detection of proteins in the sub-ug/ml range
JP2018528389A (ja) * 2015-05-12 2018-09-27 リジェネロン・ファーマシューティカルズ・インコーポレイテッド 多量体タンパク質の純度の決定
WO2019234544A1 (en) * 2018-06-04 2019-12-12 Dh Technologies Development Pte. Ltd. Lbmfi detector for fluorophore labeled analytes at the taylor cone in esi-ms
JP2020106412A (ja) * 2018-12-27 2020-07-09 パナソニックＩｐマネジメント株式会社 生体分子の検出方法及び肌状態の評価方法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
"Christopher A Dailey, Automated method for analysis of tryptophan and tyrosine metabolites using cap", ANALYTICAL AND BIOANALYTICAL CHEMISTRY, vol. 405, JPN7026000503, 2013, pages 2451 - 2459, ISSN: 0005791486 *

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US20240201131A1 (en) 2024-06-20
EP4323761A1 (en) 2024-02-21

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