JP2024513470A5 - - Google Patents

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Publication number
JP2024513470A5
JP2024513470A5 JP2023561652A JP2023561652A JP2024513470A5 JP 2024513470 A5 JP2024513470 A5 JP 2024513470A5 JP 2023561652 A JP2023561652 A JP 2023561652A JP 2023561652 A JP2023561652 A JP 2023561652A JP 2024513470 A5 JP2024513470 A5 JP 2024513470A5
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JP
Japan
Prior art keywords
independently
integer
formula
protecting group
group
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Pending
Application number
JP2023561652A
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English (en)
Japanese (ja)
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JP2024513470A (ja
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Priority claimed from PCT/EP2022/059528 external-priority patent/WO2022214692A1/en
Publication of JP2024513470A publication Critical patent/JP2024513470A/ja
Publication of JP2024513470A5 publication Critical patent/JP2024513470A5/ja
Pending legal-status Critical Current

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JP2023561652A 2021-04-09 2022-04-08 オリゴヌクレオチドおよびオリゴヌクレオチドコンジュゲートを合成するための擬似固相保護基および方法 Pending JP2024513470A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP21167583 2021-04-09
EP21167583.0 2021-04-09
PCT/EP2022/059528 WO2022214692A1 (en) 2021-04-09 2022-04-08 Pseudo solid phase protecting group and methods for the synthesis of oligonucleotides and oligonucleotide conjugates

Publications (2)

Publication Number Publication Date
JP2024513470A JP2024513470A (ja) 2024-03-25
JP2024513470A5 true JP2024513470A5 (https=) 2025-04-14

Family

ID=75441760

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023561652A Pending JP2024513470A (ja) 2021-04-09 2022-04-08 オリゴヌクレオチドおよびオリゴヌクレオチドコンジュゲートを合成するための擬似固相保護基および方法

Country Status (4)

Country Link
US (1) US20250282813A1 (https=)
EP (1) EP4320138B1 (https=)
JP (1) JP2024513470A (https=)
WO (1) WO2022214692A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024083746A1 (en) 2022-10-17 2024-04-25 Bachem Holding Ag Method and composition for oligonucleotide synthesis
EP4695265A1 (en) 2023-10-16 2026-02-18 Bachem Holding AG Method and composition for oligonucleotide synthesis

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2130844A5 (https=) 1971-03-23 1972-11-10 Commissariat Energie Atomique
AU655164B2 (en) 1989-12-20 1994-12-08 Antivirals Inc. Uncharged morpholino-based polymers having phosphorous-containing chiral intersubunit linkages
ES2615083T3 (es) 2005-09-20 2017-06-05 Jitsubo Co., Ltd. Vehículo de separación, método de separación de un compuesto, y método de síntesis del péptido utilizando el vehículo
ES2546808T3 (es) 2006-03-24 2015-09-28 Jitsubo Co., Ltd. Reactivo para síntesis orgánica y método de reacción de síntesis orgánica con dicho reactivo
WO2009073809A2 (en) 2007-12-04 2009-06-11 Alnylam Pharmaceuticals, Inc. Carbohydrate conjugates as delivery agents for oligonucleotides
DK2711370T3 (en) * 2011-05-17 2018-02-26 Ajinomoto Kk PROCEDURE FOR THE PREPARATION OF OLIGONUCLEOTIDES
CN106795200B (zh) 2014-10-10 2020-06-19 豪夫迈·罗氏有限公司 Galnac亚磷酰胺、其核酸缀合物及其用途
WO2019075419A1 (en) 2017-10-13 2019-04-18 Dicerna Pharmaceuticals, Inc. METHODS AND COMPOSITIONS FOR INHIBITING LDHA EXPRESSION
SG11202008827XA (en) 2018-04-13 2020-10-29 Bristol Myers Squibb Co Novel phosphorous (v)-based reagents, processes for the preparation thereof, and their use in making stereo-defined organophoshorous (v) compounds
JP6770553B2 (ja) 2018-07-20 2020-10-14 藤本化学製品株式会社 アルコキシフェニル誘導体、ヌクレオシド保護体およびヌクレオチド保護体、オリゴヌクレオチド製造方法、ならびに、置換基除去方法
WO2021038509A1 (en) * 2019-08-28 2021-03-04 Glaxosmithkline Intellectual Property (No.2) Limited 4'-ethynyl-2'-deoxyadenosine derivatives and their use in hiv therapy

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