JP2024509265A - 赤血球増加症を処置するための組成物および方法 - Google Patents

赤血球増加症を処置するための組成物および方法 Download PDF

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JP2024509265A
JP2024509265A JP2023555275A JP2023555275A JP2024509265A JP 2024509265 A JP2024509265 A JP 2024509265A JP 2023555275 A JP2023555275 A JP 2023555275A JP 2023555275 A JP2023555275 A JP 2023555275A JP 2024509265 A JP2024509265 A JP 2024509265A
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polycythemia
alkyl
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glyt1
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JP2024509265A5 (enExample
Inventor
ジョン クイセル，
ウィリアム ジェイコブ サベージ，
マリア ガブリエラ ベコーニ，
ヴ ホン，
ミン ウー，
イー シャン，
パヴァン レディ，
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Disc Medicine Inc
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Disc Medicine Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2023555275A 2021-03-12 2022-03-11 赤血球増加症を処置するための組成物および方法 Pending JP2024509265A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202163160412P 2021-03-12 2021-03-12
US63/160,412 2021-03-12
US202163185464P 2021-05-07 2021-05-07
US63/185,464 2021-05-07
PCT/US2022/020038 WO2022192730A1 (en) 2021-03-12 2022-03-11 Compositions and methods for treating polycythemia

Publications (2)

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JP2024509265A true JP2024509265A (ja) 2024-02-29
JP2024509265A5 JP2024509265A5 (enExample) 2025-03-11

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JP2023555275A Pending JP2024509265A (ja) 2021-03-12 2022-03-11 赤血球増加症を処置するための組成物および方法

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US (3) US20260027107A1 (enExample)
EP (1) EP4304596A4 (enExample)
JP (1) JP2024509265A (enExample)
KR (1) KR20230169981A (enExample)
AU (1) AU2022233178A1 (enExample)
BR (1) BR112023018403A2 (enExample)
CA (1) CA3213395A1 (enExample)
IL (1) IL305806A (enExample)
MX (1) MX2023010449A (enExample)
WO (1) WO2022192730A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20230169981A (ko) * 2021-03-12 2023-12-18 디스크 메디슨, 인크. 적혈구증가증을 치료하기 위한 조성물 및 방법
CN116942668A (zh) * 2023-03-17 2023-10-27 天津医科大学 Glyt1抑制剂在治疗器官纤维化中的应用
WO2025059425A1 (en) * 2023-09-15 2025-03-20 Disc Medicine, Inc. Glyt-1 inhibitors and uses thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018192973A1 (en) * 2017-04-18 2018-10-25 Vifor (International) Ag Ferroportin-inhibitor salts

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20230169981A (ko) * 2021-03-12 2023-12-18 디스크 메디슨, 인크. 적혈구증가증을 치료하기 위한 조성물 및 방법

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018192973A1 (en) * 2017-04-18 2018-10-25 Vifor (International) Ag Ferroportin-inhibitor salts

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
ANNALS OF HEMATOLOGY, vol. 94, no. 6, JPN6026017750, 2015, pages 901 - 910, ISSN: 0005852924 *
EXPERIMENTAL HEMATOLOGY, vol. 44, no. 10, JPN6026017748, 2016, pages 964 - 74, ISSN: 0005852922 *
HAEMATOLOGICA, vol. 102, no. 8, JPN6026017749, 2017, pages 1314 - 1323, ISSN: 0005852923 *

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US20250248995A1 (en) 2025-08-07
KR20230169981A (ko) 2023-12-18
BR112023018403A2 (pt) 2023-10-10
IL305806A (en) 2023-11-01
EP4304596A1 (en) 2024-01-17
CA3213395A1 (en) 2022-09-15
EP4304596A4 (en) 2025-02-19
MX2023010449A (es) 2023-11-09
WO2022192730A1 (en) 2022-09-15
AU2022233178A1 (en) 2023-10-26
US20240269132A1 (en) 2024-08-15
US20260027107A1 (en) 2026-01-29

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