JP2024509018A5 - - Google Patents
Info
- Publication number
- JP2024509018A5 JP2024509018A5 JP2023514810A JP2023514810A JP2024509018A5 JP 2024509018 A5 JP2024509018 A5 JP 2024509018A5 JP 2023514810 A JP2023514810 A JP 2023514810A JP 2023514810 A JP2023514810 A JP 2023514810A JP 2024509018 A5 JP2024509018 A5 JP 2024509018A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- amino acid
- variable region
- chain variable
- immunoglobulin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110270652 | 2021-03-12 | ||
| CN202110270652.7 | 2021-03-12 | ||
| PCT/CN2022/080107 WO2022188832A1 (zh) | 2021-03-12 | 2022-03-10 | 含有抗pd-1-抗vegfa双特异性抗体的药物组合及其用途 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024509018A JP2024509018A (ja) | 2024-02-29 |
| JP2024509018A5 true JP2024509018A5 (cg-RX-API-DMAC7.html) | 2025-03-26 |
Family
ID=83227452
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023514810A Pending JP2024509018A (ja) | 2021-03-12 | 2022-03-10 | 抗ｐｄ－１－抗ｖｅｇｆａ二重特異性抗体を含有する組合せ医薬及びその使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20250114450A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP4190819A4 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2024509018A (cg-RX-API-DMAC7.html) |
| KR (1) | KR20230156910A (cg-RX-API-DMAC7.html) |
| CN (1) | CN115068603A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2022233411A1 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112023018457A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA3193662A1 (cg-RX-API-DMAC7.html) |
| IL (1) | IL305805A (cg-RX-API-DMAC7.html) |
| MX (1) | MX2023010681A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2022188832A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115785269B (zh) * | 2022-11-01 | 2023-09-22 | 四川大学 | 抗pd-l1的抗体及其应用 |
| CN118591562A (zh) * | 2022-12-30 | 2024-09-03 | 上海荣昌生物科技有限公司 | 一种双特异性抗体及其应用 |
| CN118620082A (zh) * | 2023-03-10 | 2024-09-10 | 南京维立志博生物科技有限公司 | 靶向vegf途径和pd-1的双特异性抗原结合蛋白、其组合物和用途 |
| WO2025056056A1 (zh) * | 2023-09-14 | 2025-03-20 | 中山康方生物医药有限公司 | 药物组合及用途 |
| WO2025103407A1 (zh) * | 2023-11-16 | 2025-05-22 | 江苏豪森药业集团有限公司 | 抗体药物偶联物和多腺苷二磷酸核糖聚合酶抑制剂的联合应用 |
| WO2025157267A1 (zh) * | 2024-01-25 | 2025-07-31 | 中山康方生物医药有限公司 | 抗pd-1-抗vegfa的双特异性抗体的医药用途 |
| WO2025201450A1 (zh) * | 2024-03-27 | 2025-10-02 | 康方汇科(上海)生物有限公司 | 药物组合及用途 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US5747654A (en) | 1993-06-14 | 1998-05-05 | The United States Of America As Represented By The Department Of Health And Human Services | Recombinant disulfide-stabilized polypeptide fragments having binding specificity |
| KR100816621B1 (ko) | 1997-04-07 | 2008-03-24 | 제넨테크, 인크. | 항-ｖｅｇｆ 항체 |
| CN106967172B (zh) | 2016-08-23 | 2019-01-08 | 康方药业有限公司 | 抗ctla4-抗pd-1 双功能抗体、其药物组合物及其用途 |
| CN106977602B (zh) * | 2016-08-23 | 2018-09-25 | 中山康方生物医药有限公司 | 一种抗pd1单克隆抗体、其药物组合物及其用途 |
| TW202444417A (zh) * | 2017-05-09 | 2024-11-16 | 美商提薩羅有限公司 | 治療癌症的組合療法 |
| WO2019148412A1 (en) * | 2018-02-01 | 2019-08-08 | Merck Sharp & Dohme Corp. | Anti-pd-1/lag3 bispecific antibodies |
| CA3090878A1 (en) * | 2018-02-11 | 2019-08-15 | Beijing Hanmi Pharmaceutical Co., Ltd. | Anti-pd-1/anti-vegf natural antibody structure-like heterodimeric form bispecific antibody and preparation thereof |
| CN109053895B (zh) * | 2018-08-30 | 2020-06-09 | 中山康方生物医药有限公司 | 抗pd-1-抗vegfa的双功能抗体、其药物组合物及其用途 |
| CN112972675A (zh) * | 2018-09-07 | 2021-06-18 | 上海君实生物医药科技股份有限公司 | 抗pd-1抗体在治疗肿瘤中的用途 |
| WO2021023117A1 (zh) * | 2019-08-02 | 2021-02-11 | 康方药业有限公司 | 抗ctla4-抗pd-1双特异性抗体及其用途 |
| BR112022002028A2 (pt) * | 2019-08-02 | 2022-04-12 | Cttq Akeso Shanghai Biomed Tech Co Ltd | Anticorpo anti-pd-1 e uso farmacêutico do mesmo |
| US11661454B2 (en) * | 2019-08-09 | 2023-05-30 | Anhui Biox Vision Biological Technology Co., Ltd. | Anti-VEGF-PD1 bispecific antibody with novel structure and use thereof |
| PH12022551278A1 (en) * | 2019-11-25 | 2023-11-20 | Akeso Biopharma Inc | Anti-pd-1-anti-vegfa bispecific antibody, pharmaceutical composition and use thereof |
| CN110960543A (zh) * | 2019-12-10 | 2020-04-07 | 安徽瀚海博兴生物技术有限公司 | 一种联合抗vegf-抗pd1双特异性抗体用于制备抗癌药物 |
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2022
- 2022-03-10 EP EP22766354.9A patent/EP4190819A4/en active Pending
- 2022-03-10 US US18/024,478 patent/US20250114450A1/en active Pending
- 2022-03-10 MX MX2023010681A patent/MX2023010681A/es unknown
- 2022-03-10 CN CN202210240237.1A patent/CN115068603A/zh active Pending
- 2022-03-10 JP JP2023514810A patent/JP2024509018A/ja active Pending
- 2022-03-10 BR BR112023018457A patent/BR112023018457A2/pt active Search and Examination
- 2022-03-10 AU AU2022233411A patent/AU2022233411A1/en active Pending
- 2022-03-10 KR KR1020237030486A patent/KR20230156910A/ko active Pending
- 2022-03-10 WO PCT/CN2022/080107 patent/WO2022188832A1/zh not_active Ceased
- 2022-03-10 IL IL305805A patent/IL305805A/en unknown
- 2022-03-10 CA CA3193662A patent/CA3193662A1/en active Pending