JP2024504124A5 - - Google Patents

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Publication number
JP2024504124A5
JP2024504124A5 JP2023543120A JP2023543120A JP2024504124A5 JP 2024504124 A5 JP2024504124 A5 JP 2024504124A5 JP 2023543120 A JP2023543120 A JP 2023543120A JP 2023543120 A JP2023543120 A JP 2023543120A JP 2024504124 A5 JP2024504124 A5 JP 2024504124A5
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JP
Japan
Prior art keywords
seq
sequence
cancer
chain variable
variable region
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2023543120A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024504124A (ja
JP7879131B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/CN2022/072297 external-priority patent/WO2022152290A1/en
Publication of JP2024504124A publication Critical patent/JP2024504124A/ja
Publication of JP2024504124A5 publication Critical patent/JP2024504124A5/ja
Application granted granted Critical
Publication of JP7879131B2 publication Critical patent/JP7879131B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2023543120A 2021-01-18 2022-01-17 新規の抗グレムリン1抗体 Active JP7879131B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
CNPCT/CN2021/072397 2021-01-18
CN2021072397 2021-01-18
CN2021142043 2021-12-28
CNPCT/CN2021/142043 2021-12-28
PCT/CN2022/072297 WO2022152290A1 (en) 2021-01-18 2022-01-17 Novel anti-gremlin1 antibodies

Publications (3)

Publication Number Publication Date
JP2024504124A JP2024504124A (ja) 2024-01-30
JP2024504124A5 true JP2024504124A5 (enExample) 2025-01-24
JP7879131B2 JP7879131B2 (ja) 2026-06-23

Family

ID=82446960

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023543120A Active JP7879131B2 (ja) 2021-01-18 2022-01-17 新規の抗グレムリン1抗体

Country Status (10)

Country Link
US (1) US20240294622A1 (enExample)
EP (1) EP4277927A4 (enExample)
JP (1) JP7879131B2 (enExample)
KR (1) KR20230132544A (enExample)
CN (1) CN116848135A (enExample)
AU (1) AU2022207030A1 (enExample)
CA (1) CA3208455A1 (enExample)
MX (1) MX2023008423A (enExample)
TW (1) TW202241944A (enExample)
WO (1) WO2022152290A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20230156936A (ko) * 2021-03-11 2023-11-15 상하이 지아오통 대학 그렘린1 길항제를 사용하여 질환을 치료하는 방법
GB202205203D0 (en) * 2022-04-08 2022-05-25 UCB Biopharma SRL Combination with inhibitor
GB202205200D0 (en) * 2022-04-08 2022-05-25 Ucb Biopharma Sprl Combination with chemotherapy
KR20250169623A (ko) * 2023-04-13 2025-12-03 쑤저우 트랜스센타 테라퓨틱스 컴퍼니 리미티드 암 치료를 위한 grem1 길항제를 수반하는 조합 요법
TW202541848A (zh) * 2024-01-08 2025-11-01 中國大陸商蘇州創勝醫藥集團有限公司 用於治療pah之grem1拮抗劑及活化素受體拮抗劑的組合療法
CN117801109B (zh) * 2024-03-01 2024-05-03 再少年(北京)生物科技有限公司 iPS诱导定向分化成内皮祖细胞的方法及应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013137686A1 (ko) 2012-03-15 2013-09-19 서울대학교 산학협력단 그렘린-1에 대한 항체
BR112015021979A2 (pt) * 2013-03-14 2017-08-29 Regeneron Pharma Anticorpos humanos para grem1
CN109641954A (zh) 2016-08-29 2019-04-16 里珍纳龙药品有限公司 抗-gremlin-1(grem1)抗体及其用于治疗肺动脉高血压的使用方法
GB201621635D0 (en) 2016-12-19 2017-02-01 Ucb Biopharma Sprl Crystal structure
AU2019289176B2 (en) 2018-06-18 2026-02-19 Adelaide university Gremlin-1 antagonist for the prevention and treatment of cancer
KR20230156936A (ko) * 2021-03-11 2023-11-15 상하이 지아오통 대학 그렘린1 길항제를 사용하여 질환을 치료하는 방법

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