JP2024504124A5 - - Google Patents

Info

Publication number
JP2024504124A5
JP2024504124A5 JP2023543120A JP2023543120A JP2024504124A5 JP 2024504124 A5 JP2024504124 A5 JP 2024504124A5 JP 2023543120 A JP2023543120 A JP 2023543120A JP 2023543120 A JP2023543120 A JP 2023543120A JP 2024504124 A5 JP2024504124 A5 JP 2024504124A5
Authority
JP
Japan
Prior art keywords
seq
sequence
cancer
chain variable
variable region
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023543120A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024504124A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/CN2022/072297 external-priority patent/WO2022152290A1/en
Publication of JP2024504124A publication Critical patent/JP2024504124A/ja
Publication of JP2024504124A5 publication Critical patent/JP2024504124A5/ja
Pending legal-status Critical Current

Links

JP2023543120A 2021-01-18 2022-01-17 新規の抗グレムリン1抗体 Pending JP2024504124A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
CNPCT/CN2021/072397 2021-01-18
CN2021072397 2021-01-18
CN2021142043 2021-12-28
CNPCT/CN2021/142043 2021-12-28
PCT/CN2022/072297 WO2022152290A1 (en) 2021-01-18 2022-01-17 Novel anti-gremlin1 antibodies

Publications (2)

Publication Number Publication Date
JP2024504124A JP2024504124A (ja) 2024-01-30
JP2024504124A5 true JP2024504124A5 (enExample) 2025-01-24

Family

ID=82446960

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023543120A Pending JP2024504124A (ja) 2021-01-18 2022-01-17 新規の抗グレムリン1抗体

Country Status (10)

Country Link
US (1) US20240294622A1 (enExample)
EP (1) EP4277927A4 (enExample)
JP (1) JP2024504124A (enExample)
KR (1) KR20230132544A (enExample)
CN (1) CN116848135A (enExample)
AU (1) AU2022207030A1 (enExample)
CA (1) CA3208455A1 (enExample)
MX (1) MX2023008423A (enExample)
TW (1) TW202241944A (enExample)
WO (1) WO2022152290A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4304646A4 (en) * 2021-03-11 2025-05-28 Shanghai Jiao Tong University Methods for treating diseases with Gremlin1 antagonists
GB202205203D0 (en) * 2022-04-08 2022-05-25 UCB Biopharma SRL Combination with inhibitor
GB202205200D0 (en) * 2022-04-08 2022-05-25 Ucb Biopharma Sprl Combination with chemotherapy
CN120957750A (zh) * 2023-04-13 2025-11-14 苏州创胜医药集团有限公司 用于治疗癌症的涉及grem1拮抗剂的组合疗法
WO2025148900A1 (en) * 2024-01-08 2025-07-17 Suzhou Transcenta Therapeutics Co., Ltd. Combination therapy of grem1 antagonist and activin receptor antagonist for treating pah
CN117801109B (zh) * 2024-03-01 2024-05-03 再少年(北京)生物科技有限公司 iPS诱导定向分化成内皮祖细胞的方法及应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2826790B1 (en) * 2012-03-15 2019-02-13 SNU R&DB Foundation Anti-gremlin-1 antibody
EA201591762A1 (ru) * 2013-03-14 2015-12-30 Ридженерон Фармасьютикалз, Инк. Человеческие антитела к grem1
MA46046A (fr) * 2016-08-29 2019-07-03 Regeneron Pharma Anticorps anti-gremlin-1 (grem1) et procédés d'utilisation de ces anticorps dans le traitement de l'hypertension artérielle pulmonaire
GB201621635D0 (en) * 2016-12-19 2017-02-01 Ucb Biopharma Sprl Crystal structure
MX2020013808A (es) * 2018-06-18 2021-05-27 UCB Biopharma SRL Antagonista de gremlina-1 para la prevencion y el tratamiento del cancer.
EP4304646A4 (en) * 2021-03-11 2025-05-28 Shanghai Jiao Tong University Methods for treating diseases with Gremlin1 antagonists

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