JP2024503597A - Vegf調節ペプチド - Google Patents

Vegf調節ペプチド Download PDF

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Publication number
JP2024503597A
JP2024503597A JP2023539989A JP2023539989A JP2024503597A JP 2024503597 A JP2024503597 A JP 2024503597A JP 2023539989 A JP2023539989 A JP 2023539989A JP 2023539989 A JP2023539989 A JP 2023539989A JP 2024503597 A JP2024503597 A JP 2024503597A
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JP
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Prior art keywords
arg
leu
ser
val
seq
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Pending
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JP2023539989A
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English (en)
Japanese (ja)
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JP2024503597A5 (https=
Inventor
マルティン サンティアゴ エステバン
ラウラ ネヴォラ
ラヒャ ミゲル ラモン モレノ
アルセ マリア フェルナンダ モンテネグロ
ロペス ホセ ネプトゥーノ ロドリゲス
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アイディーピー ディスカバリー ファーマ, エセ.エレ.
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Publication of JP2024503597A publication Critical patent/JP2024503597A/ja
Publication of JP2024503597A5 publication Critical patent/JP2024503597A5/ja
Pending legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702Regulators; Modulating activity
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicinal Preparation (AREA)
JP2023539989A 2020-12-29 2021-12-29 Vegf調節ペプチド Pending JP2024503597A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP20383169.8 2020-12-29
EP20383169.8A EP4023295A1 (en) 2020-12-29 2020-12-29 Vegf-regulating peptides
PCT/EP2021/087804 WO2022144401A1 (en) 2020-12-29 2021-12-29 Vegf-regulating peptides

Publications (2)

Publication Number Publication Date
JP2024503597A true JP2024503597A (ja) 2024-01-26
JP2024503597A5 JP2024503597A5 (https=) 2025-01-09

Family

ID=74194498

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023539989A Pending JP2024503597A (ja) 2020-12-29 2021-12-29 Vegf調節ペプチド

Country Status (8)

Country Link
US (1) US20240083943A1 (https=)
EP (2) EP4023295A1 (https=)
JP (1) JP2024503597A (https=)
KR (1) KR20230127272A (https=)
CN (1) CN116964074A (https=)
AU (1) AU2021416274A1 (https=)
CA (1) CA3206857A1 (https=)
WO (1) WO2022144401A1 (https=)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006038208A2 (en) * 2004-07-12 2006-04-13 Medical Research Fund Of Tel Aviv Sourasky Medical Center Agents capable of downregulating an msf-a - dependent hif-1α and use thereof in cancer treatment
JP2012503024A (ja) * 2008-09-22 2012-02-02 エルロン・セラピューティクス・インコーポレイテッド ペプチド模倣大環状分子
WO2014138429A2 (en) * 2013-03-06 2014-09-12 Aileron Therapeutics, Inc. Peptidomimetic macrocycles and use thereof in regulating hif1alpha

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006038208A2 (en) * 2004-07-12 2006-04-13 Medical Research Fund Of Tel Aviv Sourasky Medical Center Agents capable of downregulating an msf-a - dependent hif-1α and use thereof in cancer treatment
JP2012503024A (ja) * 2008-09-22 2012-02-02 エルロン・セラピューティクス・インコーポレイテッド ペプチド模倣大環状分子
WO2014138429A2 (en) * 2013-03-06 2014-09-12 Aileron Therapeutics, Inc. Peptidomimetic macrocycles and use thereof in regulating hif1alpha

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
PNAS, vol. 92, JPN6026007011, 1995, pages 5510 - 5514, ISSN: 0005802261 *

Also Published As

Publication number Publication date
AU2021416274A1 (en) 2023-08-10
EP4023295A1 (en) 2022-07-06
EP4271480A1 (en) 2023-11-08
KR20230127272A (ko) 2023-08-31
WO2022144401A1 (en) 2022-07-07
CA3206857A1 (en) 2022-07-07
AU2021416274A9 (en) 2023-08-24
US20240083943A1 (en) 2024-03-14
CN116964074A (zh) 2023-10-27

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