JP2024503108A - 改良型アルファウイルスベクター - Google Patents

改良型アルファウイルスベクター Download PDF

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JP2024503108A
JP2024503108A JP2023543115A JP2023543115A JP2024503108A JP 2024503108 A JP2024503108 A JP 2024503108A JP 2023543115 A JP2023543115 A JP 2023543115A JP 2023543115 A JP2023543115 A JP 2023543115A JP 2024503108 A JP2024503108 A JP 2024503108A
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sequence
promoter
nucleic acid
composition
antigen
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JP2024503108A5 (https=
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スー－ジーン ホン
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グリットストーン バイオ インコーポレイテッド
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61P31/12—Antivirals
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    • A61K2039/525—Virus
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
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    • C12N2770/36011—Togaviridae
    • C12N2770/36111—Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki
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    • C12N2770/00011—Details
    • C12N2770/36011—Togaviridae
    • C12N2770/36111—Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki
    • C12N2770/36141—Use of virus, viral particle or viral elements as a vector
    • C12N2770/36143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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    • C12N2770/00011—Details
    • C12N2770/36011—Togaviridae
    • C12N2770/36111—Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki
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    • C12N2830/00—Vector systems having a special element relevant for transcription
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    • C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
    • C12N2840/203—Vectors comprising a special translation-regulating system translation of more than one cistron having an IRES

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  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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JP2023543115A 2021-01-19 2022-01-19 改良型アルファウイルスベクター Pending JP2024503108A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163139297P 2021-01-19 2021-01-19
US63/139,297 2021-01-19
PCT/US2022/013004 WO2022159511A2 (en) 2021-01-19 2022-01-19 Modified alphavirus vectors

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JP2024503108A true JP2024503108A (ja) 2024-01-24
JP2024503108A5 JP2024503108A5 (https=) 2025-01-27

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JP2023543115A Pending JP2024503108A (ja) 2021-01-19 2022-01-19 改良型アルファウイルスベクター

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US (1) US20240167057A1 (https=)
EP (1) EP4281110A4 (https=)
JP (1) JP2024503108A (https=)
KR (1) KR20230134138A (https=)
CN (1) CN117279660A (https=)
AU (1) AU2022210420A1 (https=)
CA (1) CA3205216A1 (https=)
IL (1) IL304311A (https=)
WO (1) WO2022159511A2 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022268916A2 (en) * 2021-06-23 2022-12-29 Ose Immunotherapeutics Pan-coronavirus peptide vaccine
CN119563028A (zh) * 2022-05-12 2025-03-04 尚威天成信使核糖核酸治疗公司 具有分泌抗原和免疫调节物的合成自扩增mRNA分子
WO2024026553A1 (en) * 2022-08-03 2024-02-08 Centre Hospitalier De L'université De Montréal Novel antigenic epitope against sars-cov-2 and uses thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008500399A (ja) * 2004-05-21 2008-01-10 ノバルティス ヴァクシンズ アンド ダイアグノスティクス， インコーポレイテッド 呼吸器系病原体ワクチンのためのアルファウイルスベクター
JP2020518648A (ja) * 2017-05-08 2020-06-25 グリットストーン オンコロジー インコーポレイテッド アルファウイルス新生抗原ベクター

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0814154T3 (da) * 1993-09-15 2009-08-31 Novartis Vaccines & Diagnostic Rekombinante alfavirusvektorer
RU2014118727A (ru) * 2011-10-11 2015-11-20 Новартис Аг Рекомбинантные самореплицирующиеся полицистронные молекулы рнк

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008500399A (ja) * 2004-05-21 2008-01-10 ノバルティス ヴァクシンズ アンド ダイアグノスティクス， インコーポレイテッド 呼吸器系病原体ワクチンのためのアルファウイルスベクター
JP2020518648A (ja) * 2017-05-08 2020-06-25 グリットストーン オンコロジー インコーポレイテッド アルファウイルス新生抗原ベクター

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
INFECTIOUS DISEASES OF POVERTY, JPN6025050828, 2020, ISSN: 0005751662 *
VACCINE, vol. vol. 17 no. 23-24, JPN6025050829, 1999, pages 3124 - 3135, ISSN: 0005751663 *

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Publication number Publication date
US20240167057A1 (en) 2024-05-23
EP4281110A4 (en) 2024-12-18
WO2022159511A3 (en) 2022-10-06
AU2022210420A1 (en) 2023-09-07
KR20230134138A (ko) 2023-09-20
EP4281110A2 (en) 2023-11-29
CA3205216A1 (en) 2022-07-28
IL304311A (en) 2023-09-01
WO2022159511A2 (en) 2022-07-28
CN117279660A (zh) 2023-12-22

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