JP2024501246A - 細胞中のｃｉｉｔａを遺伝子修飾するための組成物及び方法 - Google Patents

細胞中のｃｉｉｔａを遺伝子修飾するための組成物及び方法 Download PDF

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JP2024501246A
JP2024501246A JP2023537946A JP2023537946A JP2024501246A JP 2024501246 A JP2024501246 A JP 2024501246A JP 2023537946 A JP2023537946 A JP 2023537946A JP 2023537946 A JP2023537946 A JP 2023537946A JP 2024501246 A JP2024501246 A JP 2024501246A
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chr16
cell
hla
ciita
engineered
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JP2024501246A5 (https=
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フレデリック ハリントン，ウィリアム
ゴエル，スルビ
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インテリア セラピューティクス，インコーポレイテッド
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JP2023537946A 2020-12-23 2021-12-22 細胞中のｃｉｉｔａを遺伝子修飾するための組成物及び方法 Pending JP2024501246A (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US202063130098P 2020-12-23 2020-12-23
US63/130,098 2020-12-23
US202163251002P 2021-09-30 2021-09-30
US63/251,002 2021-09-30
US202163254971P 2021-10-12 2021-10-12
US63/254,971 2021-10-12
US202163288502P 2021-12-10 2021-12-10
US63/288,502 2021-12-10
PCT/US2021/064933 WO2022140587A1 (en) 2020-12-23 2021-12-22 Compositions and methods for genetically modifying ciita in a cell

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JP2024501246A true JP2024501246A (ja) 2024-01-11
JP2024501246A5 JP2024501246A5 (https=) 2025-09-02
JPWO2022140587A5 JPWO2022140587A5 (https=) 2025-09-02

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US (1) US20240139323A1 (https=)
EP (1) EP4267723A1 (https=)
JP (1) JP2024501246A (https=)
KR (1) KR20230135068A (https=)
AU (1) AU2021410751A1 (https=)
BR (1) BR112023012432A2 (https=)
CA (1) CA3205042A1 (https=)
CL (2) CL2023001855A1 (https=)
CO (1) CO2023009613A2 (https=)
CR (1) CR20230321A (https=)
IL (1) IL303970A (https=)
MX (1) MX2023007465A (https=)
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CN116042676A (zh) * 2023-01-04 2023-05-02 上海南方模式生物科技股份有限公司 一种基于CRISPR-Cas9构建TNF-α-HiBit动物模型的方法
AU2024324870A1 (en) 2023-08-14 2026-02-12 Intellia Therapeutics, Inc. Compositions and methods for genetically modifying transforming growth factor beta receptor type 2 (tgfβr2)
TW202521564A (zh) 2023-08-14 2025-06-01 美商英特利亞醫療公司 用於基於細胞之療法的ｃｄ７０ ｃａｒ－ｔ組合物及方法
TW202515994A (zh) 2023-08-14 2025-04-16 美商英特利亞醫療公司 用於對ｃｄ７０進行基因修飾之組合物及方法
WO2025038637A1 (en) 2023-08-14 2025-02-20 Intellia Therapeutics, Inc. Compositions and methods for genetically modifying transforming growth factor beta receptor type 2 (tgfβr2)
WO2025049481A1 (en) * 2023-08-28 2025-03-06 Intellia Therapeutics, Inc. Methods of editing an hla-a gene in vitro
WO2025049631A1 (en) * 2023-08-28 2025-03-06 Kyverna Therapeutics, Inc. Allogeneic car-t cell therapies and manufacture thereof
WO2025049432A1 (en) * 2023-08-28 2025-03-06 Intellia Therapeutics, Inc. Methods for editing hla-a in cells pre-screened for the absence of one or both alleles of hla-h*01
WO2025128871A2 (en) 2023-12-13 2025-06-19 Renagade Therapeutics Management Inc. Lipid nanoparticles comprising coding rna molecules for use in gene editing and as vaccines and therapeutic agents
WO2025255308A1 (en) 2024-06-07 2025-12-11 Intellia Therapeutics, Inc. Cd8 co-receptor chimeric polypeptides in tcr cell therapy

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JP2020120690A (ja) * 2013-05-15 2020-08-13 サンガモ セラピューティクス， インコーポレイテッド 遺伝的状態の処置のための方法および組成物
CN114457034A (zh) * 2020-10-30 2022-05-10 未来智人再生医学研究院(广州)有限公司 一种表达il-1阻断物的多能干细胞衍生物及其应用

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