JP2024500912A - インターロイキン５結合タンパク質の投与レジメン - Google Patents

インターロイキン５結合タンパク質の投与レジメン Download PDF

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Publication number
JP2024500912A
JP2024500912A JP2023538150A JP2023538150A JP2024500912A JP 2024500912 A JP2024500912 A JP 2024500912A JP 2023538150 A JP2023538150 A JP 2023538150A JP 2023538150 A JP2023538150 A JP 2023538150A JP 2024500912 A JP2024500912 A JP 2024500912A
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JP
Japan
Prior art keywords
seq
amino acid
acid sequence
asthma
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Prior art date
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Pending
Application number
JP2023538150A
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English (en)
Japanese (ja)
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JPWO2022136209A5 (https=
JP2024500912A5 (https=
Inventor
ダレン、ジェイ、オースティン
ニコラス、ピー、バード
マーナ、エイ、モンク
イザベル、ジェイ、プーリケン
メリッサ、エイ、シューマン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GlaxoSmithKline Intellectual Property Development Ltd
Original Assignee
GlaxoSmithKline Intellectual Property Development Ltd
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Publication date
Application filed by GlaxoSmithKline Intellectual Property Development Ltd filed Critical GlaxoSmithKline Intellectual Property Development Ltd
Priority claimed from PCT/EP2021/086689 external-priority patent/WO2022136209A1/en
Publication of JP2024500912A publication Critical patent/JP2024500912A/ja
Publication of JPWO2022136209A5 publication Critical patent/JPWO2022136209A5/ja
Publication of JP2024500912A5 publication Critical patent/JP2024500912A5/ja
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
    • A61J7/0015—Devices specially adapted for taking medicines
    • A61J7/0053—Syringes, pipettes or oral dispensers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Transplantation (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medicinal Preparation (AREA)
JP2023538150A 2020-12-22 2021-12-20 インターロイキン５結合タンパク質の投与レジメン Pending JP2024500912A (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US202063128922P 2020-12-22 2020-12-22
US63/128,922 2020-12-22
US202163192854P 2021-05-25 2021-05-25
US63/192,854 2021-05-25
US202163220182P 2021-07-09 2021-07-09
US63/220,182 2021-07-09
US202163285513P 2021-12-03 2021-12-03
US63/285,513 2021-12-03
PCT/EP2021/086689 WO2022136209A1 (en) 2020-12-22 2021-12-20 Interleukin 5 binding protein dosage regimen

Publications (3)

Publication Number Publication Date
JP2024500912A true JP2024500912A (ja) 2024-01-10
JPWO2022136209A5 JPWO2022136209A5 (https=) 2024-12-18
JP2024500912A5 JP2024500912A5 (https=) 2024-12-18

Family

ID=86732980

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023538150A Pending JP2024500912A (ja) 2020-12-22 2021-12-20 インターロイキン５結合タンパク質の投与レジメン

Country Status (5)

Country Link
US (1) US20240043524A1 (https=)
EP (2) EP4644416A3 (https=)
JP (1) JP2024500912A (https=)
CA (1) CA3199805A1 (https=)
ES (1) ES3057414T3 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2026078117A1 (en) * 2024-10-11 2026-04-16 Glaxosmithkline Intellectual Property Development Limited Anti-il-5 antibody in the treatment of chronic rhinosinusitis with nasal polyps

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014516634A (ja) * 2011-04-20 2014-07-17 アムゲン・インコーポレーテッド 自動式注射装置
JP2016528013A (ja) * 2013-08-19 2016-09-15 ドクター レディズ ラボラトリーズ リミテッド 選択可能な単一用量の自己注射器ならびにその作製および使用方法
JP2020521465A (ja) * 2017-05-26 2020-07-27 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドＧｌａｘｏｓｍｉｔｈｋｌｉｎｅ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ Ｄｅｖｅｌｏｐｍｅｎｔ Ｌｉｍｉｔｅｄ 生物医薬組成物および関連の方法
JP2020522524A (ja) * 2017-06-06 2020-07-30 グラクソスミスクライン エルエルシー 小児患者のための生物薬剤組成物及び方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11613571B2 (en) * 2018-05-23 2023-03-28 Glaxosmithkline Intellectual Property Development Limited Biopharmaceutical compositions comprising antibody variants

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014516634A (ja) * 2011-04-20 2014-07-17 アムゲン・インコーポレーテッド 自動式注射装置
JP2016528013A (ja) * 2013-08-19 2016-09-15 ドクター レディズ ラボラトリーズ リミテッド 選択可能な単一用量の自己注射器ならびにその作製および使用方法
JP2020521465A (ja) * 2017-05-26 2020-07-27 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドＧｌａｘｏｓｍｉｔｈｋｌｉｎｅ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ Ｄｅｖｅｌｏｐｍｅｎｔ Ｌｉｍｉｔｅｄ 生物医薬組成物および関連の方法
JP2020522524A (ja) * 2017-06-06 2020-07-30 グラクソスミスクライン エルエルシー 小児患者のための生物薬剤組成物及び方法

Also Published As

Publication number Publication date
ES3057414T3 (en) 2026-03-02
EP4267184B1 (en) 2025-11-26
EP4644416A3 (en) 2026-01-21
EP4644416A2 (en) 2025-11-05
EP4267184A1 (en) 2023-11-01
CA3199805A1 (en) 2022-06-30
US20240043524A1 (en) 2024-02-08

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