JP2024500064A5 - - Google Patents

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Publication number
JP2024500064A5
JP2024500064A5 JP2023534208A JP2023534208A JP2024500064A5 JP 2024500064 A5 JP2024500064 A5 JP 2024500064A5 JP 2023534208 A JP2023534208 A JP 2023534208A JP 2023534208 A JP2023534208 A JP 2023534208A JP 2024500064 A5 JP2024500064 A5 JP 2024500064A5
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JP
Japan
Prior art keywords
cancer
inhibit
activity
ability
response
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023534208A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024500064A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/061834 external-priority patent/WO2022120187A2/en
Publication of JP2024500064A publication Critical patent/JP2024500064A/ja
Publication of JP2024500064A5 publication Critical patent/JP2024500064A5/ja
Pending legal-status Critical Current

Links

JP2023534208A 2020-12-03 2021-12-03 チェックポイント阻害剤療法に対する耐性を決定する方法 Pending JP2024500064A (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US202063121083P 2020-12-03 2020-12-03
US63/121,083 2020-12-03
US202163173090P 2021-04-09 2021-04-09
US63/173,090 2021-04-09
US202163215735P 2021-06-28 2021-06-28
US63/215,735 2021-06-28
US202163276066P 2021-11-05 2021-11-05
US63/276,066 2021-11-05
PCT/US2021/061834 WO2022120187A2 (en) 2020-12-03 2021-12-03 Method of determining resistance to checkpoint inhibitor therapies

Publications (2)

Publication Number Publication Date
JP2024500064A JP2024500064A (ja) 2024-01-04
JP2024500064A5 true JP2024500064A5 (https=) 2024-12-11

Family

ID=81853603

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2023534210A Pending JP2024500065A (ja) 2020-12-03 2021-12-03 Tigitベースのキメラタンパク質及びlightベースのキメラタンパク質を使用してがんを処置する方法
JP2023534208A Pending JP2024500064A (ja) 2020-12-03 2021-12-03 チェックポイント阻害剤療法に対する耐性を決定する方法

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2023534210A Pending JP2024500065A (ja) 2020-12-03 2021-12-03 Tigitベースのキメラタンパク質及びlightベースのキメラタンパク質を使用してがんを処置する方法

Country Status (8)

Country Link
US (2) US20240011101A1 (https=)
EP (2) EP4256344A4 (https=)
JP (2) JP2024500065A (https=)
KR (1) KR20230129229A (https=)
AU (2) AU2021390545A1 (https=)
CA (2) CA3201215A1 (https=)
IL (1) IL303411A (https=)
WO (2) WO2022120191A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4426725A2 (en) * 2021-11-01 2024-09-11 Shattuck Labs, Inc. Chimeric proteins for treating cutaneous inflammation
WO2024123812A1 (en) 2022-12-05 2024-06-13 Shattuck Labs, Inc. Fusion proteins for the treatment of cardiometabolic diseases
WO2024123890A1 (en) * 2022-12-08 2024-06-13 Shattuck Labs, Inc. Methods of using light-based chimeric proteins
WO2025004683A1 (ja) * 2023-06-30 2025-01-02 国立大学法人大阪大学 がん検査方法及びがん治療剤
WO2025042798A1 (en) * 2023-08-18 2025-02-27 Shattuck Labs, Inc. Trim7 inhibitors and uses thereof
WO2025137678A1 (en) * 2023-12-22 2025-06-26 Roswell Park Cancer Institute Corporation Targeting the pvr axis using car t cell therapy and combinations

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005074633A2 (en) * 2004-02-03 2005-08-18 The Regents Of The University Of Michigan Compositions and methods for characterizing, regulating, diagnosing, and treating cancer
CA2608359A1 (en) * 2005-05-13 2006-11-23 Duke University Gene expression signatures for oncogenic pathway deregulation
JP6981973B2 (ja) * 2015-10-01 2021-12-17 ヒート バイオロジクス,インコーポレイテッド I型及びii型細胞外ドメインを異種キメラタンパク質として連結する組成物及び方法
CA3002587A1 (en) * 2015-10-23 2017-04-27 Apogenix Ag Single-chain light receptor agonist proteins
WO2017161188A1 (en) * 2016-03-16 2017-09-21 The Regents Of The University Of California Detection and treatment of anti-pd-1 therapy resistant metastatic melanomas
MX2019006072A (es) * 2016-11-30 2019-08-14 Oncomed Pharm Inc Metodos para tratamiento de cancer que comprenden agentes de enlace al inmunoreceptor de celulas t con dominios ige itim (tigit).
US20190367579A1 (en) * 2017-02-27 2019-12-05 Shattuck Labs, Inc. Tigit- and light-based chimeric proteins
CN111868260B (zh) * 2017-08-07 2025-02-21 约翰斯霍普金斯大学 用于评估和治疗癌症的方法和材料
US20200071380A1 (en) * 2018-08-29 2020-03-05 Shattuck Labs, Inc. Combination therapies comprising sirp alpha-based chimeric proteins
EP3930851A4 (en) * 2019-02-28 2023-03-29 Shattuck Labs, Inc. COMBINATION THERAPIES
WO2025188614A1 (en) * 2024-03-04 2025-09-12 Shattuck Labs, Inc. Peptide inhibitors of trim7 and uses thereof

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