JP2024154382A5 - - Google Patents
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- Publication number
- JP2024154382A5 JP2024154382A5 JP2024061950A JP2024061950A JP2024154382A5 JP 2024154382 A5 JP2024154382 A5 JP 2024154382A5 JP 2024061950 A JP2024061950 A JP 2024061950A JP 2024061950 A JP2024061950 A JP 2024061950A JP 2024154382 A5 JP2024154382 A5 JP 2024154382A5
- Authority
- JP
- Japan
- Prior art keywords
- pip2
- pathway
- abcb5
- compound
- level
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862662670P | 2018-04-25 | 2018-04-25 | |
| US62/662,670 | 2018-04-25 | ||
| JP2020560247A JP7611701B2 (ja) | 2018-04-25 | 2019-04-25 | Ａｂｃｂ５のリガンドおよび基質 |
| PCT/US2019/029235 WO2019210109A1 (en) | 2018-04-25 | 2019-04-25 | Abcb5 ligands and substrates |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020560247A Division JP7611701B2 (ja) | 2018-04-25 | 2019-04-25 | Ａｂｃｂ５のリガンドおよび基質 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024154382A JP2024154382A (ja) | 2024-10-30 |
| JP2024154382A5 true JP2024154382A5 (enExample) | 2024-11-29 |
Family
ID=68295729
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020560247A Active JP7611701B2 (ja) | 2018-04-25 | 2019-04-25 | Ａｂｃｂ５のリガンドおよび基質 |
| JP2024061950A Pending JP2024154382A (ja) | 2018-04-25 | 2024-04-08 | Ａｂｃｂ５のリガンドおよび基質 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020560247A Active JP7611701B2 (ja) | 2018-04-25 | 2019-04-25 | Ａｂｃｂ５のリガンドおよび基質 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US12448461B2 (enExample) |
| EP (1) | EP3784249A4 (enExample) |
| JP (2) | JP7611701B2 (enExample) |
| KR (2) | KR20260025888A (enExample) |
| CN (1) | CN112423765B (enExample) |
| AU (2) | AU2019257728A1 (enExample) |
| CA (1) | CA3097875A1 (enExample) |
| MX (1) | MX2020011297A (enExample) |
| SG (1) | SG11202010260XA (enExample) |
| WO (1) | WO2019210109A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2685492C (en) | 2006-05-31 | 2018-01-16 | The Brigham And Women's Hospital, Inc. | Abcb5 positive mesenchymal stem cells as immunomodulators |
| US11542328B2 (en) | 2008-11-14 | 2023-01-03 | The Brigham And Women's Hospital, Inc. | Therapeutic and diagnostic methods relating to cancer stem cells |
| BR112015028193B8 (pt) | 2013-05-10 | 2023-04-18 | Childrens Medical Center | Suporte para cicatrização de feridas |
| CN111007240A (zh) * | 2019-12-02 | 2020-04-14 | 中国医学科学院北京协和医院 | 一种基于crispr技术的均相酶免疫检验系统及其方法和应用 |
| CA3180226A1 (en) * | 2020-04-15 | 2021-10-21 | Children's Medical Center Corporation | Targeting abcb5 in glioblastoma multiforme |
| CN113082210B (zh) * | 2021-03-09 | 2023-04-18 | 广州白云山医药集团股份有限公司白云山制药总厂 | 一种肿瘤化疗药物组合物 |
| CN116445573A (zh) * | 2022-08-30 | 2023-07-18 | 苏州大学 | 一种以抑制trim54泛素化降解stat2为靶点的抗病毒ade药物筛选方法 |
Family Cites Families (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3587465T2 (de) | 1984-09-10 | 1994-01-20 | Hsc Res Dev Corp | Vielfache Drogen-Resistenz in Säugetierzellinien und Isolierung der determinanten Glykoprotein-DNS. |
| US5837258A (en) | 1991-08-30 | 1998-11-17 | University Of South Florida | Induction of tissue, bone or cartilage formation using connective tissue growth factor |
| DE69739540D1 (de) | 1996-04-19 | 2009-10-01 | Osiris Therapeutics Inc | Die wiederherstellung und verstärkung von knochen mittels mesenchymalen stammzellen |
| US6152142A (en) | 1997-02-28 | 2000-11-28 | Tseng; Scheffer C. G. | Grafts made from amniotic membrane; methods of separating, preserving, and using such grafts in surgeries |
| DE69922933T2 (de) | 1998-03-13 | 2005-12-29 | Osiris Therapeutics, Inc. | Anwendungen für humane nicht autologe, mesenchymale stammzellen |
| US6368636B1 (en) | 1998-03-18 | 2002-04-09 | Osiris Therapeutics, Inc. | Mesenchymal stem cells for prevention and treatment of immune responses in transplantation |
| CA2266805C (en) | 1998-03-27 | 2015-04-28 | An-Go-Gen Inc. | Cell-based gene therapy in the treatment of pulmonary disorders |
| JP2002510655A (ja) | 1998-04-03 | 2002-04-09 | オシリス セラピューティクス，インコーポレイテッド | 免疫抑制剤としての間葉幹細胞によるｔ細胞応答を阻害する方法とその利用 |
| WO1999061587A1 (en) | 1998-05-29 | 1999-12-02 | Osiris Therapeutics, Inc. | Human cd45+ and/or fibroblast + mesenchymal stem cells |
| AU785363B2 (en) | 1999-09-28 | 2007-02-01 | Gentest Corporation | P-glycoproteins and uses thereof |
| US6673606B1 (en) | 2000-04-12 | 2004-01-06 | The Children's Hospital Of Philadelphia | Therapeutic uses for mesenchymal stromal cells |
| CA2411101C (en) | 2000-06-05 | 2018-01-16 | Brigham And Women's Hospital, Inc. | A gene encoding a multidrug resistance human p-glycoprotein homologue on chromosome 7p15-21 and uses thereof |
| US20040175366A1 (en) | 2003-03-07 | 2004-09-09 | Acell, Inc. | Scaffold for cell growth and differentiation |
| US7829336B2 (en) | 2003-11-24 | 2010-11-09 | The Rockefeller University | Method for isolating a self-renewing, multipotent, slow-cycling cell |
| US20050186672A1 (en) | 2004-01-27 | 2005-08-25 | Reliance Life Sciences Pvt. Ltd. | Tissue system with undifferentiated stem cells derived from corneal limbus |
| WO2006103685A2 (en) | 2005-03-28 | 2006-10-05 | Vision Research Foundation | A method for cultivating cells derived from corneal limbal tissue and cells deived from corneal limbal tissue |
| US8883507B2 (en) | 2005-10-18 | 2014-11-11 | The Regents Of The University Of Colorado | Conditionally immortalized long-term hematopoietic stem cells and methods of making and using such cells |
| WO2007112097A2 (en) | 2006-03-24 | 2007-10-04 | Children's Medical Center Corporation | Novel signature self renewal gene expression programs |
| CA2685492C (en) | 2006-05-31 | 2018-01-16 | The Brigham And Women's Hospital, Inc. | Abcb5 positive mesenchymal stem cells as immunomodulators |
| GB0610778D0 (en) * | 2006-05-31 | 2006-07-12 | Het Nl Kanker I | Phosphatidylinositol phospahte and apoptosis |
| EP2052089A4 (en) | 2006-07-28 | 2010-05-05 | Chundsell Medicals Ab | EMBRYONIC STEM CELL MARKERS FOR CANCER DIAGNOSIS AND PROGNOSIS |
| WO2008064244A2 (en) | 2006-11-20 | 2008-05-29 | The Trustees Of Columbia University In The City Of New York | Phosphoinositide modulation for the treatment of neurodegenerative diseases |
| PL2155248T3 (pl) | 2007-04-12 | 2015-12-31 | Brigham & Womens Hospital Inc | Celowanie w ABCB5 w terapii nowotworowej |
| US9011840B2 (en) | 2008-03-14 | 2015-04-21 | The Board Of Trustees Of The University Of Illinois | Activated mesenchymal stem cells for wound healing and impaired tissue regeneration |
| US11542328B2 (en) | 2008-11-14 | 2023-01-03 | The Brigham And Women's Hospital, Inc. | Therapeutic and diagnostic methods relating to cancer stem cells |
| ES2796111T3 (es) | 2008-11-14 | 2020-11-25 | Brigham & Womens Hospital Inc | Métodos terapéuticos relacionados con células madre cancerosas |
| WO2010065711A1 (en) * | 2008-12-04 | 2010-06-10 | Adimab, Inc. | An abcb5 epitope and antibodies thereto for the treatment of cancer |
| KR101138091B1 (ko) | 2011-08-31 | 2012-04-24 | 세원셀론텍(주) | 중간엽 줄기세포 기본 배양 배지 조성방법, 중간엽 줄기세포 기본 배양 배지 및 이를 이용하여 배양분화된 세포치료제 |
| ES2860573T3 (es) | 2013-02-19 | 2021-10-05 | Childrens Medical Center | Células madre ABCB5(+) para el tratamiento de enfermedades oculares |
| BR112015028193B8 (pt) * | 2013-05-10 | 2023-04-18 | Childrens Medical Center | Suporte para cicatrização de feridas |
| US20180134771A1 (en) * | 2015-05-07 | 2018-05-17 | Bioxcel Corporation | Novel immunomodulatory therapeutic strategies targeting tumors in cancer |
| WO2016184793A1 (en) * | 2015-05-15 | 2016-11-24 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for treating a patient with vegfr inhibitor-resistant metastatic renal cell carcinoma |
| EP4036228A1 (en) | 2015-11-13 | 2022-08-03 | Avellino Lab USA, Inc. | Methods for the treatment of corneal dystrophies |
| WO2018185584A1 (en) | 2017-04-05 | 2018-10-11 | Pluristem Ltd. | Methods and compositions for treating acute lung injury and respiratory distress syndrome |
| JP7849972B2 (ja) | 2019-03-28 | 2026-04-22 | ザ チルドレンズ メディカル センター コーポレーション | 高機能な製造されたａｂｃｂ５＋間葉系幹細胞 |
| JP7714535B2 (ja) | 2019-10-18 | 2025-07-29 | アムニオティクス・アーベー | 羊水およびそれに由来する細胞から羊水間葉系幹細胞を得るためのプロセスならびに装置 |
| US20230148432A1 (en) | 2020-03-30 | 2023-05-11 | Children's Medical Center Corporation | Use of stem cells for treatment of excessive inflammation |
| CA3180226A1 (en) | 2020-04-15 | 2021-10-21 | Children's Medical Center Corporation | Targeting abcb5 in glioblastoma multiforme |
| JP2023524102A (ja) | 2020-04-30 | 2023-06-08 | ザ チルドレンズ メディカル センター コーポレーション | Ａｂｃｂ５に特異的な抗体およびその使用 |
-
2019
- 2019-04-25 CA CA3097875A patent/CA3097875A1/en active Pending
- 2019-04-25 EP EP19793673.5A patent/EP3784249A4/en active Pending
- 2019-04-25 KR KR1020267004454A patent/KR20260025888A/ko active Pending
- 2019-04-25 JP JP2020560247A patent/JP7611701B2/ja active Active
- 2019-04-25 KR KR1020207033473A patent/KR102928177B1/ko active Active
- 2019-04-25 US US17/050,424 patent/US12448461B2/en active Active
- 2019-04-25 AU AU2019257728A patent/AU2019257728A1/en not_active Abandoned
- 2019-04-25 WO PCT/US2019/029235 patent/WO2019210109A1/en not_active Ceased
- 2019-04-25 SG SG11202010260XA patent/SG11202010260XA/en unknown
- 2019-04-25 CN CN201980027801.8A patent/CN112423765B/zh active Active
- 2019-04-25 MX MX2020011297A patent/MX2020011297A/es unknown
-
2024
- 2024-04-08 JP JP2024061950A patent/JP2024154382A/ja active Pending
-
2025
- 2025-03-13 AU AU2025201810A patent/AU2025201810A1/en active Pending
- 2025-09-25 US US19/340,094 patent/US20260184810A1/en active Pending
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