JP2024085384A - Sheet for application to the body - Google Patents

Abstract

[Problem] To provide a sheet for application to the body that has high movement-following ability even when the sheet has a large basis weight of hydrous gel, and has excellent durability of effects such as cooling effect, especially in areas with large and frequent movements such as the neck, shoulders, and joints such as the knees.
[Solution] A body application sheet having a support and a gel layer laminated on the support, wherein the gel layer contains the following components: (A) water, (B) a water-soluble polymer having a ^COO- group, and (C) aluminum atoms, the content of component (A) in the gel layer is from 50% by mass to 85% by mass, the bulk softness of a layer consisting of the support and the gel layer is from 0.15 N to 0.50 N, and the basis weight is from 1000 g/ ^m2 to 2600 g/ ^m2 , and the ball number of the gel layer in a ball tack test performed in accordance with JIS Z0237:2009 under conditions of an inclined plate angle of 30°, a temperature of 23°C, and 50% R.H. is from 14 to 30.
[Selection diagram] None

Description

The present invention relates to a sheet for application to the body.

A sheet with a gel layer to be applied to the body (hydrous gel sheet) has been developed for use in a variety of applications, such as cooling during fever or inflammation, cooling down after sports, and relieving stiff shoulders by improving blood circulation.
For example, Patent Document 1 discloses a patch that is difficult to peel off from the skin, and that comprises a supporting substrate and an aqueous gel laminated over the entire area of one side of the supporting substrate, and in which the supporting substrate has a higher elongation rate in one of a first direction and a second direction perpendicular to the first direction when viewed in a plane, than the elongation rate in the other direction.
Patent Document 2 discloses a patch having a base composition and a support, with the aim of providing a patch which increases shape retention when spread to prevent back staining due to pressure, and decreases shape retention when used to provide an excellent patch that follows the movement of the skin, the base composition containing (A) polyacrylic acid and neutralized polyacrylic acid: a total amount of 7 to 15 mass % and a content mass ratio expressed as polyacrylic acid/neutralized polyacrylic acid of 1.5 to 3.0, (B) one or more types selected from carboxymethylcellulose and salts thereof, (C) glycerin, (D) a crosslinking agent: 0.5 mass % or less, and (E) water: 50 to 80 mass %.

JP 2019-208692 A JP 2022-98096 A

Such body application sheets are applied to the body while performing various movements in daily life, and therefore are required to have high ability to follow body movements (motion-following ability) in order to obtain the desired effects continuously.
However, for example, in a hydrogel sheet for cooling, in order to maintain the cooling effect for a long period of time, it is necessary to increase the moisture content and basis weight of the gel layer, which makes the sheet thicker. Also, not only for cooling purposes, but also when a physiologically active gas is to be contained, it is sometimes necessary to increase the moisture content and basis weight of the gel layer in order to ensure the content of the gas.
As a result, conventional body application sheets tend to peel off easily, particularly when applied to areas with large and frequent movements, such as the neck, shoulders, or joints such as the knees, and there is still room for improvement in terms of movement tracking.

The present invention relates to a sheet for application to the body that has excellent movement-following properties even when the basis weight of the hydrogel (gel layer) is large, and has excellent durability of effects such as cooling, even in areas with large and frequent movements, such as the neck, shoulders, and joints such as the knees.

As a result of intensive research, the inventors have found that the above-mentioned problems can be solved by providing a sheet having a specified configuration, in which the gel layer has a specified composition, and the bulk softness and basis weight of the layer consisting of the support and the gel layer, as well as the ball number in a ball tack test of the gel layer, are within specific ranges.
That is, the present invention relates to the following.
[1] A sheet for application to the body having a support and a gel layer laminated on the support,
The gel layer comprises the following components (A) to (C):
(A) water; (B) a water-soluble polymer having a ^COO- group; (C) an aluminum atom-containing polymer;
The content of the component (A) in the gel layer is 50% by mass or more and 85% by mass or less,
The layer consisting of the support and the gel layer has a bulk softness of 0.15 N or more and 0.50 N or less, and a basis weight of 1000 g/m ² or more and 2600 g/m ² or less,
The gel layer has a ball number of 14 or more and 30 or less in a ball tack test performed according to JIS Z0237:2009 under conditions of an inclined plate angle of 30°, a temperature of 23° C., and 50% R.H.

According to the present invention, a sheet with a high basis weight of hydrous gel can achieve high movement tracking, and a sheet for application to the body that has excellent durability of effects such as cooling effect can be provided, especially in areas with large and frequent movements such as the neck, shoulders, and joints such as the knees.

FIG. 13 is a diagram showing the locations at which skin temperature was measured in the evaluation of the durability of the cooling effect in the examples.

The body application sheet of the present invention will now be described.
[Body application sheet]
The sheet for application to the body of the present invention (hereinafter, simply referred to as "the sheet of the present invention") is a sheet for application to the body having a support and a gel layer laminated on the support,
The gel layer comprises the following components (A) to (C):
(A) water; (B) a water-soluble polymer having a ^COO- group; (C) an aluminum atom-containing polymer;
The content of the component (A) in the gel layer is 50% by mass or more and 85% by mass or less,
The layer consisting of the support and the gel layer has a bulk softness of 0.15 N or more and 0.50 N or less, and a basis weight of 1000 g/m ² or more and 2600 g/m ² or less,
The gel layer has a ball number of 14 or more and 30 or less in a ball tack test performed according to JIS Z0237:2009 under conditions of an inclined plate angle of 30°, a temperature of 23° C., and 50% R.H.
Because the body application sheet of the present invention has the above-mentioned configuration, it can obtain high movement tracking even in a sheet with a large basis weight of hydrogel, and has excellent durability of effects such as cooling effect, especially in areas with large and frequent movements such as the neck, shoulders, and joints such as the knees.

The present inventors applied a sheet for body application to the body and observed it for several hours. They noticed that the sheet with poor conformability had few wrinkles and peeled off, whereas the sheet with good conformability had several fine wrinkles but little peeling off, and focused on the relationship between conformability and flexibility of the sheet. On the other hand, in order to effectively obtain the desired effect of the sheet, the adhesion at the time of application is important. As a result of intensive research, the present inventors found that by setting the value of bulk softness, which is one of the indicators of "softness (flexibility)", and the ball number of the ball tack test, which is an indicator of adhesion, within a specific range, high movement conformability can be obtained even in a sheet with a large basis weight of hydrogel, and that the effect such as cooling effect is excellent in durability, especially in areas with large and frequent movements such as the neck, shoulders, and joints such as the knees.
Conventionally, the only way to improve the movement tracking is to make the sheet thinner, and when the thickness of the sheet is increased to improve the duration of the cooling effect, etc., the movement tracking is insufficient. However, according to the configuration of the present invention, the movement tracking can be improved more than that of conventional body application sheets, so that high movement tracking can be achieved even if the basis weight of the gel layer of the body application sheet is increased. As a result, a high cooling effect can be obtained. The gel layer has a predetermined composition, and the bulk softness and basis weight of the layer consisting of the support and the gel layer, and the ball number value of the ball tack test in the gel layer are set to a specific range, so that the high basis weight and movement tracking of the hydrogel can be achieved at the same time. This makes it possible to fully exert the functions of the body application sheet, such as cooling.

<Gel layer>
The gel layer contained in the body patch sheet of the present invention comprises the following components (A) to (C):
(A) water; (B) a water-soluble polymer having a ^COO- group; (C) an aluminum atom-containing polymer;
The content of the component (A) in the gel layer is 50% by mass or more and 85% by mass or less,
The layer consisting of the support and the gel layer has a bulk softness of 0.15 N or more and 0.50 N or less, and a basis weight of 1000 g/m ² or more and 2600 g/m ² or less,
The gel layer has a ball number of 14 or more and 30 or less in a ball tack test performed in accordance with JIS Z0237:2009 under conditions of an inclined plate angle of 30°, a temperature of 23° C., and 50% R.H.
The sheet of the present invention having the gel layer has high movement-following ability, particularly in areas with large and frequent movements such as the neck, shoulders, and joints such as the knees, and is excellent in sustaining effects such as cooling effect.

(Physical properties of gel layer)
In the present invention, the viscous and elastic properties of the gel layer can be evaluated using the loss tangent (tan δ) as an index. A gel layer with a larger loss tangent value has a higher viscous property.

More specifically, the gel layer constituting the sheet of the present invention has a loss tangent in dynamic viscoelasticity measurement at a temperature of 25° C. and a frequency of 0.1 Hz, preferably 0.15 or more, more preferably 0.20 or more, even more preferably 0.22 or more, even more preferably 0.25 or more, and even more preferably 0.28 or more, from the viewpoint of reducing the bulk softness of the sheet and improving its movement followability. Also, from the viewpoint of improving the handling property, such as suppressing excessive stickiness when the sheet is applied, the loss tangent is preferably 0.70 or less, more preferably 0.60 or less, even more preferably 0.58 or less, even more preferably 0.50 or less, and even more preferably 0.35 or less. The loss tangent of the gel layer constituting the sheet of the present invention, as measured by dynamic viscoelasticity at a temperature of 25° C. and a frequency of 0.1 Hz, is preferably 0.15 or more and 0.70 or less, more preferably 0.20 or more and 0.60 or less, even more preferably 0.22 or more and 0.58 or less, still more preferably 0.25 or more and 0.58 or less, still more preferably 0.28 or more and 0.50 or less, and still more preferably 0.28 or more and 0.35 or less.
Specifically, the loss tangent of the gel layer can be measured by the method described in the Examples.

Tackiness is an index of adhesive strength that can be exerted in a short time with light force. In other words, a sheet with high tackiness indicates high adhesion immediately after application to the skin. In addition, in the configuration of the present invention, this adhesive strength is thought to be maintained while the sheet is applied, which is also thought to contribute to improved movement tracking.
More specifically, the ball number of the gel layer in a ball tack test performed according to JIS Z0237:2009 under conditions of an inclined plate angle of 30°, a temperature of 23° C., and 50% R.H. is 14 or more, preferably 16 or more, and more preferably 18 or more, from the viewpoint of improving adhesion to the body (skin) and movement tracking. In addition, from the viewpoint of improving handling such as suppressing excessive stickiness when the sheet is applied and from the viewpoint of reducing the burden on the skin, the ball number is 30 or less, preferably 28 or less, more preferably 26 or less, and even more preferably 23 or less. The ball number is 14 or more and 30 or less, preferably 14 or more and 28 or less, more preferably 16 or more and 26 or less, and even more preferably 18 or more and 23 or less.
Specifically, the ball tack test can be carried out by the method described in the Examples.

Each component contained in the gel layer will be described below.
(Component (A): Water)
The gel layer constituting the sheet of the present invention contains water, and therefore the application site can be cooled by the heat of vaporization of water, and the active ingredients, such as medicinal ingredients and cooling ingredients, which are optionally contained in the sheet, can be effectively penetrated into the skin.
As component (A), for example, purified water such as deionized water, distilled water, highly pure water, and ultrapure water can be used.
The content of component (A) in the gel layer is 50% by mass or more, preferably 55% by mass or more, more preferably 60% by mass or more, and even more preferably 65% by mass or more, from the viewpoint of improving the cooling effect and allowing the active ingredient having the desired efficacy contained as necessary to effectively penetrate the skin. Also, from the viewpoint of improving the movement tracking, it is 85% by mass or less, preferably 80% by mass or less, more preferably 78% by mass or less, and even more preferably 77% by mass or less. The content of component (A) in the gel layer is 50% by mass or more and 85% by mass or less, preferably 55% by mass or more and 80% by mass or less, more preferably 60% by mass or more and 78% by mass or less, and even more preferably 65% by mass or more and 77% by mass or less.

(Component (B): Water-soluble polymer having ^COO- groups)
The gel layer constituting the sheet of the present invention contains a water-soluble polymer having a COO ² -group as component (B).
The water-soluble polymer having a ^COO- group used in the present invention can form a crosslinked structure by ionic interaction with a trivalent aluminum ion, which is an ionized product of an aluminum atom (C) described below, since it has a ^COO- group. The water-soluble polymer having a ^COO- group may have a COOH group in the same molecule.
The water-soluble polymer having a ^COO- group may be a water-soluble polymer (B1) having a carboxy group and/or a salt thereof, which is capable of providing a carboxy ion ( ^COO- ) in the gel layer. Among these, from the viewpoint of obtaining a hydrogel that satisfies particularly high water retention capacity, sufficient gel strength, and flexibility capable of following unevenness and movement, it is preferable to use one or more selected from the group consisting of carboxymethylcellulose and its salts, and polyacrylic acid and its salts, and it is more preferable to use one or more selected from the group consisting of carboxymethylcellulose and its salts.

Examples of the salt of carboxymethylcellulose include alkali metal salts such as sodium salt and potassium salt, ammonium salt, etc. From the viewpoints of availability and improving operational followability, etc., the salt of carboxymethylcellulose is preferably an alkali metal salt of carboxymethylcellulose, and more preferably a sodium salt of carboxymethylcellulose (sodium carboxymethylcellulose).
Examples of the salt of polyacrylic acid include alkali metal salts such as sodium salt and potassium salt, and ammonium salt. From the viewpoint of availability and improvement of operation tracking, the salt of polyacrylic acid is preferably an alkali metal salt of polyacrylic acid, and more preferably a sodium salt of polyacrylic acid (sodium polyacrylate). The salt of polyacrylic acid may be a fully neutralized polyacrylic acid in which all the carboxy groups of polyacrylic acid are neutralized, or a partially neutralized polyacrylic acid in which a part of the carboxy groups are neutralized.
Examples of commercially available sodium carboxymethylcellulose used as component (B) include the CMC Daicel series manufactured by Daicel Corp. and the Sunrose series manufactured by Nippon Paper Industries Co., Ltd. Examples of commercially available polyacrylic acid or a salt thereof used as component (B) include the Aronvis series and the Julimer series manufactured by Toagosei Co., Ltd. and the Aqualic series manufactured by Nippon Shokubai Co., Ltd.

One or more types of component (B) can be used. Among them, from the viewpoints of availability and improved operational tracking, component (B) is preferably one or more types selected from the group consisting of carboxymethylcellulose and sodium carboxymethylcellulose, and more preferably sodium carboxymethylcellulose.

In addition, when carboxymethylcellulose and/or its salt is used as component (B), the content of component (B) in the gel layer is preferably 1% by mass or more, more preferably 1.5% by mass or more, more preferably 2% by mass or more, even more preferably 2.3% by mass or more, even more preferably 2.5% by mass or more from the viewpoint of obtaining a suitable shape retention of the gel layer.In addition, from the viewpoint of improving the movement followability and improving the handling property such as suppressing excessive stickiness when the sheet is applied, it is preferably 5% by mass or less, more preferably 4% by mass or less, even more preferably 3.8% by mass or less, even more preferably 3.4% by mass or less.The content of component (B) in the gel layer is preferably 1% by mass or more and 5% by mass or less, more preferably 1.5% by mass or more and 4% by mass or less, even more preferably 2% by mass or more and 3.8% by mass or less, even more preferably 2.3% by mass or more and 3.4% by mass or less, even more preferably 2.5% by mass or more and 3.4% by mass or less.
In addition, when component (B) is a salt of carboxymethylcellulose, the content of component (B) in the gel layer means the content as a salt. However, when component (B) forms a crosslinked structure with component (C), the content of component (B) does not include the content of component (C). The same applies to the salt of polyacrylic acid.

When polyacrylic acid and/or a salt thereof is used as component (B), the content of component (B) in the gel layer is preferably 3% by mass or more, more preferably 4% by mass or more, even more preferably 4.5% by mass or more, and even more preferably 5% by mass or more, from the viewpoint of improving the shape retention and adhesiveness (tackiness) of the gel layer. And, from the viewpoint of improving the movement tracking ability, suppressing an excessive increase in viscosity, and improving the handling property such as suppressing excessive stickiness when the sheet is applied, it is preferably 10% by mass or less, more preferably 9% by mass or less, even more preferably 8% by mass or less, and even more preferably 7% by mass or less. And, the content of component (B) in the gel layer is preferably 3% by mass or more and 10% by mass or less, more preferably 4% by mass or more and 9% by mass or less, even more preferably 4.5% by mass or more and 8% by mass or less, and even more preferably 5% by mass or more and 7% by mass or less.

(Component (C): Aluminum atom)
The gel layer constituting the sheet of the present invention contains aluminum atoms as component (C). The trivalent aluminum ions, which are the ionized product of component (C), can act as a crosslinking agent for component (B), and it is believed that a crosslinked structure is formed in the gel layer by ionic interaction with component (B).
The source of aluminum atoms, which is component (C), is not particularly limited as long as it is an aluminum-containing compound (hereinafter also referred to as "component (C1)"), but is preferably an inorganic metal salt containing aluminum from the viewpoint of ease of supply as aluminum ions capable of crosslinking component (B) and high solubility in the gel-forming composition during gel layer formation.

Examples of the aluminum-containing compound (C1) which can act as a crosslinking agent for component (B) and which serves as a supply source of component (C) include aluminum hydroxide, aluminum magnesium hydroxide, sodium aluminate, aluminum sulfate, aluminum potassium sulfate, aluminum ammonium sulfate, aluminum carbonate, aluminum nitrate, aluminum chloride, magnesium aluminium (meth)silicate, aluminum acetate, aluminum lactate, aluminum stearate, aluminum myristate, aluminum glycinate, aluminum benzoate, and aluminum allantoin chlorohydroxylate, and one or more of these can be used.
Among the above, from the viewpoint of ease of supplying aluminum ions and from the viewpoint of high solubility and good dispersibility in the gel-forming composition when forming the gel layer, component (C1) is preferably one or more selected from the group consisting of aluminum hydroxide and magnesium aluminosilicate (meta)silicate. Also, from the viewpoint of improving the adhesiveness of the sheet and improving the movement followability, component (C1) preferably contains two or more aluminum-containing compounds, more preferably contains at least magnesium aluminosilicate (meta)silicate, and even more preferably is aluminum hydroxide and magnesium aluminosilicate (meta)silicate.

The content of component (C) in the gel layer is preferably 0.002% by mass or more, more preferably 0.003% by mass or more, even more preferably 0.004% by mass or more, and even more preferably 0.0045% by mass or more, from the viewpoint of improving the handling property such as suppressing excessive stickiness when the sheet is applied. Also, from the viewpoint of reducing the bulk softness of the sheet, improving the adhesion, and improving the movement tracking property, it is preferably 0.05% by mass or less, more preferably 0.03% by mass or less, even more preferably 0.02% by mass or less, even more preferably 0.01% by mass or less, and even more preferably 0.0080% by mass or less. The content of component (C) in the gel layer is preferably 0.002 mass% or more and 0.05 mass% or less, more preferably 0.003 mass% or more and 0.03 mass% or less, even more preferably 0.004 mass% or more and 0.02 mass% or less, still more preferably 0.004 mass% or more and 0.01 mass% or less, and still more preferably 0.0045 mass% or more and 0.0080 mass% or less.
The content of component (C) in the gel layer can be measured according to the 18th Edition of the Japanese Pharmacopoeia, General Test Methods, Inductively Coupled Plasma Atomic Emission Spectroscopy and Inductively Coupled Plasma Mass Spectroscopy. Either the plasma atomic emission spectroscopic analysis or the inductively coupled plasma mass spectrometry can be used.

The mass ratio [(B)/(C)] in the gel layer is preferably 200 or more, more preferably 300 or more, and even more preferably 400 or more, from the viewpoint of reducing the bulk softness of the sheet, improving adhesion, and improving movement tracking. Also, from the viewpoint of improving handling such as suppressing excessive stickiness when the sheet is applied, it is preferably 800 or less, more preferably 700 or less, and even more preferably 600 or less. The mass ratio [(B)/(C)] in the gel layer is preferably 200 or more and 800 or less, more preferably 300 or more and 800 or less, even more preferably 400 or more and 700 or less, and even more preferably 400 or more and 600 or less.

(Component (D): Polyvinyl alcohol)
The gel layer constituting the sheet of the present invention preferably further contains polyvinyl alcohol (D). By containing component (D) in addition to components (B) and (C), the tackiness and viscous properties in the low frequency range of the gel layer are improved, thereby improving adhesion to the body (skin) and movement tracking ability.

The weight average molecular weight of component (D) is not particularly limited, but from the viewpoint of obtaining an appropriate shape retention of the gel layer, it is preferably 30,000 or more, more preferably 50,000 or more, and even more preferably 70,000 or more. Also, from the viewpoint of improving the tackiness of the gel layer to improve the adhesiveness and movement followability of the sheet, it is preferably 150,000 or less, more preferably 140,000 or less, and even more preferably 130,000 or less. And, the weight average molecular weight of component (D) is preferably 30,000 or more and 150,000 or less, more preferably 50,000 or more and 140,000 or less, and even more preferably 70,000 or more and 130,000 or less.
When the weight average molecular weight of component (D) is preferably 150,000 or less, more preferably 140,000 or less, and even more preferably 130,000 or less, it is believed that the entanglement of the polymer chains of component (D) in the gel layer is reduced, and a gel structure that is more easily deformed can be formed. This effect is believed to further improve the tackiness of the gel layer, and also improve its adhesion to the body (skin) and its ability to follow movements.
The weight average molecular weight of the powdery raw material of component (D) is obtained by measuring an aqueous solution of the powdery raw material dissolved in water by size exclusion chromatography (SEC) under the following conditions. Note that "powdered raw material of component (D)" means component (D) in a powder state before being blended into the gel layer or the gel-forming composition described below. The weight average molecular weight of component (D) in the gel layer is obtained by measuring an extract of the gel layer by SEC under the following conditions.
<SEC measurement conditions>
Measuring device: "SEC-8320" manufactured by Tosoh Corporation
Eluent: 0.2 mol/L phosphate buffer/acetonitrile = 9/1 (v/v%)
Guard column: "PWXL (6 mm x 4 cm)" manufactured by Tosoh Corporation
Analytical column: Tosoh Corporation "G4000PWxL + G2500PWxL (7.8 mm x 30 cm)
Flow rate: 1 mL/min
Column temperature: 40°C
Injection volume: 100 μL
Sample size: 1 mg/mL
Molecular weight conversion standard: PEO manufactured by Tosoh Corporation (SE-150 (977,000), SE-70 (580,000), SE-30 (394,000), SE-15 (143,000), SE-8 (101,000), SE-2 (21,000))
Detector: RI

The saponification degree of component (D) is preferably 75 mol% or more, more preferably 82 mol% or more, and even more preferably 85 mol% or more from the viewpoint of improving the tackiness of the gel layer and thereby improving the adhesion of the sheet to the skin. The saponification degree of component (D) may be 100 mol% or less, and from the viewpoint of increasing the water solubility of component (D) and improving its handling property, it is preferably 98 mol% or less, more preferably 96 mol% or less. The saponification degree of component (D) is preferably 75 mol% or more and 98 mol% or less, more preferably 82 mol% or more and 98 mol% or less, and even more preferably 85 mol% or more and 96 mol% or less.
The degree of saponification of component (D) can be measured in accordance with JIS K6726:1994.

Component (D) is preferably unmodified polyvinyl alcohol, but modified polyvinyl alcohol into which ionic groups or the like have been introduced can also be used as required.
However, it is preferable that component (D) contains a small amount of functional groups capable of forming a crosslinked structure by ionic interaction with aluminum ions, in order not to inhibit the formation of a crosslinked structure of component (B). For example, the content of carboxyl groups in component (D) is preferably 0.1 mol% or less, more preferably 0.01 mol% or less, and even more preferably 0 mol%.

Examples of commercially available polyvinyl alcohols that can be used as component (D) include the Gohsenol series manufactured by Nippon Synthetic Chemical Industry Co., Ltd., the Kuraray Poval series manufactured by Kuraray Co., Ltd., and the J Poval series manufactured by Nippon Vinyl Acetate & Poval Co., Ltd.

When the gel layer contains component (D), the content of component (D) in the gel layer is preferably 2% by mass or more, more preferably 7% by mass or more, and even more preferably 9% by mass or more, from the viewpoint of improving adhesion to the body (skin) and improving movement tracking. Also, from the viewpoint of improving handling such as suppressing excessive stickiness when the sheet is applied, it is preferably 18% by mass or less, more preferably 16% by mass or less, even more preferably 15% by mass or less, even more preferably 12% by mass or less, and even more preferably 11% by mass or less. And, the content of component (D) in the gel layer is preferably 2% by mass or more and 18% by mass or less, more preferably 7% by mass or more and 16% by mass or less, even more preferably 9% by mass or more and 15% by mass or less, even more preferably 9% by mass or more and 12% by mass or less, and even more preferably 9% by mass or more and 11% by mass or less.

The content of component (D) in the gel layer can be obtained by measuring an extract of the gel layer by ¹ H-NMR under the following conditions.
< ^1H -NMR Measurement Conditions>
Measuring device: JEOL "MR-400"
Observed nucleus: ¹ H
Frequency: 300 MHz or more Pulse delay time: 25 seconds Number of integrations: 32 times Mode: Presaturation
Solvent: _D2O
Internal standard: 0.1% sodium trimethylpropionate
Sample size: 10 mg/mL

The mass ratio [(D)/(B)] in the gel layer is preferably 0.1 or more, more preferably 1 or more, even more preferably 2 or more, and even more preferably 3 or more, from the viewpoint of improving adhesion to the body (skin) and improving movement tracking. Also, from the viewpoint of improving handling such as suppressing excessive stickiness when the sheet is applied, it is preferably 7 or less, more preferably 6 or less, even more preferably 5 or less, and even more preferably 4 or less. The mass ratio [(D)/(B)] in the gel layer is preferably 0.1 or more and 7 or less, more preferably 1 or more and 7 or less, even more preferably 2 or more and 6 or less, even more preferably 3 or more and 6 or less, even more preferably 3 or more and 5 or less, and even more preferably 3 or more and 4 or less.

From the viewpoint of obtaining the effects of the present invention, the total content of the components (A) to (D) in the gel layer is preferably 70% by mass or more, more preferably 80% by mass or more, and even more preferably 85% by mass or more, and is 100% by mass or less.

(Other ingredients)
The gel layer may contain other components than the above-mentioned components (A) to (D) as appropriate, provided that the object of the present invention is not impaired. Examples of other components include components that are commonly used in cosmetics, fragrances, medicines, quasi-drugs, etc.
Examples of ingredients commonly used in these products include moisturizers, skin whitening agents, blood circulation promoters, anti-inflammatory agents, germicides, UV absorbers, colorants, preservatives, antioxidants, fragrances, oils, pH adjusters, chelating agents, water retention agents, medicines, cooling agents (cooling agents), warming agents, and alcohols.
A physiologically active gas such as carbon dioxide gas may also be contained. When a physiologically active gas is contained, the content of each component is the content in the total amount of the gel layer excluding the physiologically active gas.

The basis weight of the gel layer is preferably 900 g/m ² or more, more preferably 1100 g/m ² or more, even more preferably 1150 g/m ² or more, and even more preferably 1200 g/m 2 or more, from the viewpoint of providing a sustained cooling effect, and is preferably 2500 g/m ² or less, more preferably 2000 g/m ² or less, even more preferably 1500 g/m ² or less, and even more preferably 1400 g/m ² or less, from the viewpoint of improving adhesion to the body (skin) and movement tracking. And, it is preferably 900 g/m ² or more and 2500 g/m ² or less, more preferably 1100 g/m ² or more and 2000 g/m ² or less, even more ^preferably 1150 g/m ² or more and 1500 g/m ² or less, and even more preferably 1200 g/m ² or more and 1400 g/m ² or less.
The thickness of the gel layer is preferably 0.8 mm or more, more preferably 1.0 mm or more, and even more preferably 1.2 mm or more from the viewpoint of providing a sustained cooling effect, and is preferably 5.0 mm or less, more preferably 4.0 mm or less, even more preferably 3.0 mm or less, even more preferably 2.5 mm or less, and even more preferably 2.0 mm or less from the viewpoint of improving adhesion to the body (skin) and improving movement tracking. And, it is preferably 0.8 mm or more and 5.0 mm or less, more preferably 0.8 mm or more and 4.0 mm or less, even more preferably 1.0 mm or more and 3.0 mm or less, even more preferably 1.0 mm or more and 2.5 mm or less, and even more preferably 1.2 mm or more and 2.0 mm or less.

<Gel-forming composition>
The gel layer constituting the sheet of the present invention comprises the following components (A) to (C):
The gel layer can be formed using a gel-forming composition containing (A) water, (B) a water-soluble polymer having a ^COO- group, and (C) an aluminum atom, and the content of the component (A) is 50% by mass or more and 85% by mass or less. The gel-forming composition may also contain a component (D) and other components as necessary. In the present invention, the content of each component in the gel layer can be considered to be the same as the content of each component in the gel-forming composition used to form the gel layer.

The gel layer constituting the sheet of the present invention comprises the following components (A), (B1) and (C1):
The gel can be formed using a gel-forming composition containing (A) water, (B1) a water-soluble polymer having a carboxy group and/or a salt thereof, and (C1) an aluminum-containing compound, wherein the content of component (A) is 50% by mass or more and 85% by mass or less.
The components (A), (B1), (C1), and optional component (D), other components, and their preferred embodiments contained in the gel-forming composition are the same as those described in the gel layer unless otherwise specified. The amount and preferred range of the components (A) and optional (D) contained in the gel-forming composition are the same as the content and preferred range of the components (A) and optional (D) in the gel layer. The amount and preferred range of the components (B1) contained in the gel-forming composition are the same as the content and preferred range of the components (B) in the gel layer.

In the gel-forming composition, the content of component (B) relative to the content of component (C1) (mass ratio [(B)/(C1)]) is preferably 25 or more, more preferably 50 or more, and even more preferably 60 or more, from the viewpoint of reducing the bulk softness of the sheet, improving adhesion, and improving movement tracking. In addition, from the viewpoint of improving handleability, particularly from the viewpoint of suppressing excessive stickiness when the sheet is applied, it is preferably 250 or less, more preferably 150 or less, even more preferably 120 or less, even more preferably 100 or less, and even more preferably 95 or less. The mass ratio [(B)/(C1)] is preferably 25 or more and 250 or less, more preferably 25 or more and 150 or less, even more preferably 50 or more and 120 or less, even more preferably 50 or more and 100 or less, and even more preferably 60 or more and 95 or less. The preferred range of the content of component (B1) relative to the content of component (C1) (mass ratio [(B1)/(C1)]) is the same as the preferred range of the mass ratio [(B)/(C1)].

The amount of component (C1) contained in the gel-forming composition may be an amount such that the mass ratio [(B)/(C1)] falls within the above range. From the viewpoint of improving the handling property, particularly from the viewpoint of suppressing excessive stickiness when the sheet is applied, the amount in the gel-forming composition is preferably 0.005% by mass or more, more preferably 0.01% by mass or more, and even more preferably 0.02% by mass or more. In addition, from the viewpoint of reducing the bulk softness of the sheet, improving the adhesion, and improving the movement tracking property, the amount is preferably 0.2% by mass or less, more preferably 0.1% by mass or less, even more preferably 0.06% by mass or less, and even more preferably 0.04% by mass or less. The amount of component (C1) contained in the gel-forming composition is preferably 0.005% by mass or more and 0.2% by mass or less, more preferably 0.005% by mass or more and 0.1% by mass or less, even more preferably 0.01% by mass or more and 0.06% by mass or less, and even more preferably 0.02% by mass or more and 0.04% by mass or less.

From the viewpoint of obtaining the effects of the present invention, the total content of the components (A), (B) (or (B1)), (C1) and, if necessary, (D) in the gel-forming composition is preferably 70% by mass or more, more preferably 80% by mass or more, even more preferably 85% by mass or more, and is 100% by mass or less.

The gel-forming composition may contain crosslinking agent components other than component (C1) to the extent that the effects of the present invention are not impaired, but it is preferable that the content is small. The content of crosslinking agent components other than component (C1) is preferably 10% by mass or less, more preferably 5% by mass or less, and even more preferably 0% by mass, of the total crosslinking agent components.

There are no particular limitations on the method for preparing the gel-forming composition, but when component (D) is used, it is preferable to prepare an aqueous solution of component (D) in advance by dissolving it in water, and mix it with the other components in the form of an aqueous solution. After that, all of the other components may be added to a kneader and mixed, or some of the components may be mixed or dispersed and then added to the kneader and mixed.

<Configuration of the body application sheet>
The body application sheet of the present invention has a support and a gel layer laminated on the support. A release film may be laminated on the surface of the gel layer on which the support is not laminated. The release film is used to protect the gel layer, and is a film that is peeled off from the gel layer when the sheet is applied, and can be, for example, a non-axially oriented polypropylene film, a biaxially oriented polypropylene film, a polyethylene terephthalate film, etc. Among these, from the viewpoint of providing excellent releasability, those that are embossed are preferred, and embossed non-axially oriented polypropylene films are more preferred.
From the viewpoint of improving the handleability of the sheet, the sheet for application to the body of the present invention preferably has a three-layer structure having a support, a gel layer, and a release film in this order.
The shape of the sheet for application to the body is not particularly limited, but from the viewpoint of improving ease of application, it preferably has an outer shape (longitudinal shape) in which the length in a first direction in a plan view is longer than the length in a second direction perpendicular thereto, and examples of such shapes include a rectangular shape, an elliptical shape (oval shape), etc.

(Support)
As the support constituting the sheet of the present invention, a sheet-like substrate such as a woven fabric, a nonwoven fabric, a biased cloth, a synthetic resin film, a waterproof paper, etc. Also, a laminated substrate formed by laminating a plurality of such sheet-like substrates can be used.
Specific examples of the material include woven or nonwoven synthetic fibers such as nylon, polyolefin (e.g., polyethylene, polypropylene, etc.), polyester (e.g., polyethylene terephthalate, etc.), polystyrene, polyurethane, etc.; woven or nonwoven natural fibers such as silk, cotton, hemp, rayon, collagen, etc.; films made of synthetic resins such as nylon, polypropylene, polyester, polyethylene, polyurethane, etc.; sheet-like substrates made of pullulan, starch, etc.; and laminated substrates formed by laminating a plurality of these.
Among the above, from the viewpoint of improving the handling property of the sheet, the ease of laminating the gel layer, and the conformability, the support is preferably a nonwoven fabric, and the material (substance) of the nonwoven fabric is preferably polyester, more preferably polyethylene terephthalate. These materials can be used alone or in combination of two or more kinds.
In addition, polyethylene terephthalate (PET) here includes copolymers of polyethylene terephthalate (coPET). That is, PET alone may be used as the material for the nonwoven fabric, or a mixture of PET/coPET may be used.

The method for producing the nonwoven fabric is not particularly limited, but examples thereof include the meltblown method, the spunbond method, the air-through method, the airlaid method, the spunlace method, the needle punch method, the electrospinning method, the chemical bond method, and the thermal bond method. The nonwoven fabric may also be produced by any combination of these methods. Among these, from the viewpoint of reducing the bulk softness of the sheet and improving the movement tracking ability, the spunlace method or the needle punch method is preferable, and the needle punch method is more preferable.

The thickness of the support varies depending on the material constituting the support, and is not particularly limited, but from the viewpoint of improving the handling property of the sheet and the ease of laminating the gel layer, it is preferably 0.1 mm or more, more preferably 0.3 mm or more, and even more preferably 0.5 mm or more, and from the viewpoint of reducing the bulk softness of the sheet and improving the movement followability, it is preferably 3 mm or less, more preferably 2 mm or less, even more preferably 1.5 mm or less, even more preferably 1.2 mm or less, and even more preferably 1.0 mm or less. And the thickness of the support is preferably 0.1 mm or more and 3 mm or less, more preferably 0.1 mm or more and 2 mm or less, even more preferably 0.3 mm or more and 1.5 mm or less, even more preferably 0.3 mm or more and 1.2 mm or less, and even more preferably 0.5 mm or more and 1.0 mm or less.
The basis weight of the support varies depending on the material constituting the support and is not particularly limited, but from the viewpoint of improving the handling property of the sheet and the ease of laminating the gel layer, it is preferably 10 g/m ² or more, more preferably 30 g/m ² or more, and even more preferably 50 g/m ² or more, and from the viewpoint of reducing the bulk softness of the sheet and improving the movement followability, it is preferably 200 g/m ² or less, more preferably 150 g/m ² or less, and even more preferably 120 g/m ² or less. The basis weight of the support is preferably 10 g/m 2 or more and 200 g/m ² or less, more preferably 30 g/m ² or more and 150 g/m ^{2 or} less, and even more preferably 50 g/m ² or more and 120 g/m ² or less.

The bulk softness in the MD direction of the support is preferably 0.15 N or more, more preferably 0.20 N or more, even more preferably 0.25 N or more, and even more preferably 0.30 N or more, from the viewpoint of improving the handling property of the sheet and the ease of laminating the gel layer, and is preferably 0.60 N or less, more preferably 0.50 N or less, even more preferably 0.45 N or less, even more preferably 0.38 N or less, and even more preferably 0.34 N or less, from the viewpoint of improving the movement tracking property. The bulk softness in the MD direction of the support (nonwoven fabric) is preferably 0.15 N or more and 0.60 N or less, more preferably 0.20 N or more and 0.50 N or less, even more preferably 0.25 N or more and 0.45 N or less, even more preferably 0.25 N or more and 0.34 N or less, even more preferably 0.30 N or more and 0.38 N or less, and even more preferably 0.30 N or more and 0.34 N or less.
The bulk softness of the support (nonwoven fabric) in the MD direction can be measured specifically by the method described in the Examples. That is, under the conditions of 23°C and 50% R.H., the support is cut out to a size of 150 mm in the CD direction and 30 mm in the MD direction of the support. This is made into a ring shape with a diameter of about 45 mm, with both ends of the CD direction of the support overlapping by 10 mm, and the center of the CD direction of the overlapping portion is fixed at two points, one above and one below, near both ends of the MD direction of the support, using a stapler. Using a tensile tester, the ring is erected in a cylindrical shape on a sample stand, and the maximum load is measured when the ring is compressed from above with a flat plate approximately parallel to the stand at a compression speed of 10 mm/min, and this is the bulk softness of the support. The stapler core is fixed so that it is long in the CD direction of the support (i.e., parallel to the CD direction of the support).
The smaller the bulk softness value, the higher the flexibility.

From the viewpoint of improving the handleability of the sheet, the strength at 50% elongation in the CD direction of the support is preferably 0.3 N/5cm or more, more preferably 0.5 N/5cm or more, even more preferably 0.8 N/5cm or more, and even more preferably 1.2 N/5cm or more, and from the viewpoint of improving motion tracking, it is preferably 4.5 N/5cm or less, more preferably 4.0 N/5cm or less, even more preferably 3.5 N/5cm or less, even more preferably 3 N/5cm or less, even more preferably 2.5 N/5cm or less, and even more preferably less than 2 N/5cm. The strength of the support at 50% elongation in the CD direction is preferably 0.3 N/5cm or more and 4.5 N/5cm or less, more preferably 0.5 N/5cm or more and 4.0 N/5cm or less, even more preferably 0.5 N/5cm or more and 3.5 N/5cm or less, still more preferably 0.8 N/5cm or more and 3 N/5cm or less, still more preferably 0.8 N/5cm or more and 2.5 N/5cm or less, still more preferably 0.8 N/5cm or more and less than 2 N/5cm, and still more preferably 1.2 N/5cm or more and less than 2 N/5cm.
The elongation recovery rate of the support at 50% elongation in the CD direction is preferably 50% or more, more preferably 55% or more, even more preferably 60% or more, and even more preferably 70% or more from the viewpoint of improving the handleability of the sheet, and is preferably 85% or less, more preferably 80% or less, and even more preferably 75% or less from the viewpoint of improving the movement tracking. The elongation recovery rate of the support at 50% elongation in the CD direction is preferably 50% or more and 85% or less, more preferably 55% or more and 80% or less, even more preferably 60% or more and 75% or less, and even more preferably 70% or more and 75% or less.
The larger the elongation recovery rate at 50% elongation, the stronger the ability to return to the original shape.
The strength at 50% elongation and the elongation recovery rate at 50% elongation of the support can be specifically measured by the method described in the Examples.

The MD direction of the support refers to the machine direction (MD: Machine Direction) in the production of the nonwoven fabric, which is the material of the support. For example, when the nonwoven fabric is rolled as a raw roll, or when it is unrolled from the rolled state, it means the direction in which the nonwoven fabric is unrolled. On the other hand, the CD direction refers to the width direction (CD: Cross Direction) perpendicular to the MD direction. In the raw roll state, it means the roll axial direction.
In addition, the body application sheet of the present invention is preferably applied so that the CD direction of the support constituting the body application sheet of the present invention is the direction of the greatest body movement at the application site, specifically, the direction in which the body bends or rotates. More specifically, for example, the direction of rotation in the case of the neck, and the direction of flexion in the case of the elbow or knee.
Furthermore, when the nonwoven fabric is cut to a predetermined size to be used as the support of the body application sheet, it is preferable that the CD direction is the same as the longitudinal direction of the body application sheet, and the MD direction is the same as the width direction of the body application sheet.Generally, the stress generated when the nonwoven fabric is stretched is stronger in the MD direction than in the CD direction.For example, when the body application sheet is applied to the neck, the sheet is applied so that the long side is parallel to the circumferential direction of the neck, but if the nonwoven fabric is arranged as described above, the CD direction of the nonwoven fabric is arranged in the direction in which the neck moves greatly in the movement of rotating left and right, which is common in daily life, and the stress generated in the sheet by the movement of the neck is well absorbed, and the movement tracking of the sheet is improved.In other words, by applying the body application sheet so that the CD direction of the nonwoven fabric is parallel to the direction of large body movement, the stress generated in the sheet when the body moves can be absorbed, and the movement tracking of the sheet is excellent.
As mentioned above, the stress generated when a nonwoven fabric is stretched is generally stronger in the MD direction than in the CD direction. Therefore, the orientation (MD direction, CD direction) of the nonwoven fabric constituting the body patch sheet can be confirmed by measuring the stress when the nonwoven fabric is stretched in the longitudinal direction and the stress when it is stretched in the lateral direction separately (for example, the strength at 50% elongation), and comparing the stress when stretched in the longitudinal direction and the stress when it is stretched in the lateral direction, so that the direction of stretch with the larger value is the MD direction and the direction of stretch with the smaller value is the CD direction.

(Layer consisting of support and gel layer)
The layer (hereinafter, simply referred to as "laminate") consisting of a support and a gel layer constituting the body application sheet has a basis weight of 1000 g/ ^m2 or more, preferably 1050 g/m2 or more, more preferably 1100 g/ ^m2 or more, even more preferably 1150 g/ ^{m2 or} more, still more preferably 1200 g/ ^m2 or more, still more preferably 1250 g/ ^m2 or more, from the viewpoint of improving the durability of the cooling effect, and from the viewpoint of improving adhesion to the body (skin) and movement tracking, it is 2600 g/ ^m2 or less, preferably 2400 g/ ^m2 or less, more preferably 2200 g/ ^m2 or less, even more preferably 2100 g/ ^m2 or less, still more preferably 2000 g/ ^m2 or less, and still more preferably 1500 g/ ^m2 or less. The layer consisting of the support and the gel layer has ^a basis weight of 1000 g/m2 or more and 2600 g/ ^m2 or less, preferably 1050 g/ ^m2 or more and 2400 g/ ^m2 or less, more preferably 1100 g/ ^m2 or more and 2200 g/ ^m2 or less, even more preferably 1150 g/ ^m2 or more and 2100 g/ ^m2 or less, still more preferably 1200 g/ ^m2 or more and 2000 g/ ^m2 or less, and still more preferably 1250 g/ ^m2 or more and 1500 g/ ^m2 or less.
In the configuration of the present invention, the bulk softness tends to be greater when the basis weight of the laminate is large, and tends to be smaller when the basis weight of the laminate is small. Therefore, the bulk softness can be adjusted by the basis weight of the laminate.
The bulk softness of the layer consisting of the support and the gel layer constituting the body patch sheet is 0.15 N or more, preferably 0.20 or more, from the viewpoint of improving the handling property of the sheet, and 0.50 N or less, preferably 0.45 N or less, more preferably 0.40 N or less, and even more preferably 0.35 N or less, from the viewpoint of improving the movement tracking property. The bulk softness of the layer consisting of the support and the gel layer is 0.15 N or more and 0.50 N or less, preferably 0.15 N or more and 0.45 N or less, more preferably 0.15 N or more and 0.40 N or less, even more preferably 0.15 N or more and 0.35 N or less, and even more preferably 0.20 N or more and 0.35 N or less.
The bulk softness of the layer (laminate) consisting of the support and the gel layer can be measured by the method described in the examples.That is, using a body application sheet made so that the CD direction of the support (nonwoven fabric) is the longitudinal direction in plan view, the body application sheet is cut into a size of 80 mm in the longitudinal direction of the sheet and 20 mm in the width direction perpendicular to the longitudinal direction under the conditions of 23 ° C. and 50% R.H., and then peel off the release film, and with the support facing outward, the longitudinal ends of the sheet are made into a ring shape with a diameter of about 25 mm so that there is no overlap and no gap (i.e., the longitudinal ends of the sheet are butted against each other), and the vicinity of both ends in the width direction of the sheet is fixed at two points, top and bottom, using a stapler, so as to straddle the longitudinal ends of the sheet. Using a tensile tester, the ring is set up in a cylindrical shape on a sample stand, and compressed from above with a flat plate of about 60 mm in diameter that is nearly parallel to the stand at a compression rate of 10 mm/min. The maximum load is measured, and this is taken as the bulk softness of the layer consisting of the gel layer and the support. The stapler core is fixed so that it is long in the longitudinal direction of the sheet (i.e., parallel to the longitudinal direction of the sheet).
The smaller the bulk softness of the laminate, the higher its flexibility.

Moreover, the value y obtained from the following formula (1), which shows the relationship between the bulk softness a of the layer consisting of the support and the gel layer and the ball number b of the gel layer in the ball tack test, is preferably 0.38 or more, more preferably 0.40 or more, even more preferably 0.43 or more, and is preferably 1.00 or less, more preferably 0.80 or less, even more preferably 0.70 or less, and even more preferably 0.60 or less, from the viewpoint of improving the movement tracking ability. And, y is preferably 0.38 or more and 1.00 or less, more preferably 0.40 or more and 0.80 or less, even more preferably 0.43 or more and 0.70 or less, and even more preferably 0.43 or more and 0.60 or less.
y = -a + 0.04b ... (1)
(In formula (1), a is the bulk softness (N), and b is the ball number in the ball tack test.)

[Manufacturing method of body application sheet]
The method for producing the body patch sheet of the present invention is not particularly limited, but it can be efficiently produced by a production method including the following steps (I) to (III) in this order.
Step (I) The following components (A), (B1), (C1) and, if necessary, (D):
(A) water; (B1) a water-soluble polymer having a carboxy group and/or a salt thereof; (C1) an aluminum-containing compound; and (D) polyvinyl alcohol,
The content of component (A) is 50% by mass or more and 85% by mass or less.
A step of preparing a gel-forming composition.
Step (II): Filling the gel-forming composition between the support and the release film to produce a laminated sheet having the support, the gel-forming composition layer, and the release film in that order. Step (III): Sealing the laminated sheet in a package, and then crosslinking the gel-forming composition layer in the package.

<Step (I)>
In step (I), the following components (A), (B1), (C1) and, if necessary, (D):
A gel-forming composition is prepared containing (A) water, (B1) a water-soluble polymer having a carboxy group and/or a salt thereof, (C1) an aluminum-containing compound, and (D) polyvinyl alcohol, and the content of the component (A) is 50% by mass or more and 85% by mass or less. The gel-forming composition and the preparation method thereof, as well as preferred embodiments thereof, are as described above.

<Step (II)>
In the step (II), the gel-forming composition is filled between the support and the release film to prepare a laminated sheet having the support, the gel-forming composition layer, and the release film in that order. The support and the release film are as described above.
Examples of the method of filling the gel-forming composition between the support and the release film and laminating the composition include a method of sandwiching the gel-forming composition between the support and the release film, and then spreading it to a desired thickness using a Baker-type applicator or the like; a method of applying the gel-forming composition to a desired thickness on the release film, and then laminating the support; and the like. Alternatively, the support and the release film can be made to face each other and run on a conveying roll, and the gel-forming composition can be filled between the support and the release film, and the gel-forming composition can be sent out while being pressed by the roll to form a laminated sheet. At this time, the thickness of the gel-forming composition layer can be adjusted to a desired thickness by adjusting the distance between the two rolls.
The laminated sheet obtained in step (II) is cut to a desired size, if necessary, and then subjected to step (III).

<Step (III)>
In step (III), the laminated sheet obtained in step (II) is sealed in a package, and then the gel-forming composition layer is crosslinked in the package, thereby forming a gel layer having a crosslinked structure.

The packaging used in step (III) preferably has moisture barrier properties, and from the viewpoint of suppressing the evaporation of volatile components in the packaging and from the viewpoint of improving storage stability, it is more preferable that the packaging has gas barrier properties. Specific examples of such packaging include packaging having at least a layer made of silicon, aluminum, or an oxide thereof. From the viewpoint of improving moisture barrier properties and gas barrier properties, and from the viewpoint of economy, the packaging preferably includes an aluminum layer.

The crosslinking conditions for the gel-forming composition layer are not particularly limited, but from the viewpoint of improving the productivity of the gel-forming composition and the body patch sheet having a gel layer made of the composition, the crosslinking temperature is preferably 15 to 60°C, more preferably 15 to 30°C, and the crosslinking time (aging time) is preferably 1 to 21 days, more preferably 1 to 14 days.

The sheet for application to the body obtained by carrying out steps (I) to (III) can be made into a product in a sealed state in a package. When using the sheet for application to the body, it is removed from the package, the release film is peeled off, and the gel layer surface is applied to the body.

The body application sheet of the present invention is applied to the outer skin (excluding the scalp). There are no particular limitations on the part of the body that can be applied, but it has high movement tracking ability and excellent durability of effects such as cooling effect, especially in parts of the body that move a lot, such as the neck, shoulders, and joints such as the knees.

In relation to the above-mentioned embodiments, the present invention further discloses the following.
<1> A sheet for application to the body having a support and a gel layer laminated on the support,
The gel layer comprises the following components (A) to (C):
(A) water; (B) a water-soluble polymer having a ^COO- group; (C) an aluminum atom-containing polymer;
The content of the component (A) in the gel layer is 50% by mass or more and 85% by mass or less,
The layer consisting of the support and the gel layer has a bulk softness of 0.15 N or more and 0.50 N or less, and a basis weight of 1000 g/m ² or more and 2600 g/m ² or less,
The gel layer has a ball number of 14 or more and 30 or less in a ball tack test performed according to JIS Z0237:2009 under conditions of an inclined plate angle of 30°, a temperature of 23° C., and 50% R.H.
<2> The body patch sheet according to <1>, wherein the component (B) has a crosslinked structure crosslinked by the component (C).
<3> A sheet for application to the body having a support and a gel layer laminated on the support,
The gel layer comprises the following components (A) to (C):
(A) water; (B) a water-soluble polymer having a ^COO- group; and (C) an aluminum atom-containing gel-forming composition, the gel being formed using the gel-forming composition having a content of the component (A) of 50% by mass or more and 85% by mass or less.
The layer consisting of the support and the gel layer has a bulk softness of 0.15 N or more and 0.50 N or less, and a basis weight of 1000 g/m ² or more and 2600 g/m ² or less,
The gel layer has a ball number of 14 or more and 30 or less in a ball tack test performed according to JIS Z0237:2009 under conditions of an inclined plate angle of 30°, a temperature of 23° C., and 50% R.H.
<4> The body patch sheet according to any one of <1> to <3>, wherein a value y obtained from the following formula (1), which shows the relationship between the bulk softness a of the layer consisting of the support and the gel layer and the ball number b of the gel layer in a ball tack test, is 0.38 or more and 1.00 or less.
y = -a + 0.04b ... (1)
(In formula (1), a is the bulk softness (N), and b is the ball number in the ball tack test.)
<5> The body patch sheet according to <4>, wherein the value y obtained from the formula (1) is preferably 0.38 or more, more preferably 0.40 or more, even more preferably 0.43 or more, and is preferably 1.00 or less, more preferably 0.80 or less, even more preferably 0.70 or less, and still more preferably 0.60 or less.
<6> The body patch sheet according to any one of <1> to <5>, wherein the content of component (A) in the gel layer is preferably 55% by mass or more, more preferably 60% by mass or more, even more preferably 65% by mass or more, and is preferably 80% by mass or less, more preferably 78% by mass or less, even more preferably 77% by mass or less.
<7> The body patch sheet according to any one of <1> to <6>, wherein, when carboxymethylcellulose and/or a salt thereof is used as the component <B>, the content of component (B) in the gel layer is preferably 1% by mass or more, more preferably 1.5% by mass or more, even more preferably 2% by mass or more, still more preferably 2.3% by mass or more, still more preferably 2.5% by mass or more, and is preferably 5% by mass or less, more preferably 4% by mass or less, even more preferably 3.8% by mass or less, and still more preferably 3.4% by mass or less.
<8> The body patch sheet according to any one of <1> to <7>, wherein, when polyacrylic acid and/or a salt thereof is used as the component (B), the content of component (B) in the gel layer is preferably 3% by mass or more, more preferably 4% by mass or more, even more preferably 4.5% by mass or more, still more preferably 5% by mass or more, and is preferably 10% by mass or less, more preferably 9% by mass or less, even more preferably 8% by mass or less, and still more preferably 7% by mass or less.
<9> The body patch sheet according to any one of <1> to <8>, wherein the content of component (C) in the gel layer is preferably 0.002% by mass or more, more preferably 0.003% by mass or more, even more preferably 0.004% by mass or more, still more preferably 0.0045% by mass or more, and is preferably 0.05% by mass or less, more preferably 0.03% by mass or less, even more preferably 0.02% by mass or less, still more preferably 0.01% by mass or less, and still more preferably 0.0080% by mass or less.
<10> The body patch sheet according to any one of <1> to <9>, wherein the mass ratio [(B)/(C)] in the gel layer is preferably 200 or more, more preferably 300 or more, even more preferably 400 or more, and is preferably 800 or less, more preferably 700 or less, even more preferably 600 or less.
<11> The body patch sheet according to any one of <1> to <10>, wherein the content of component (D) in the gel layer is preferably 2% by mass or more, more preferably 7% by mass or more, even more preferably 9% by mass or more, and is preferably 18% by mass or less, more preferably 16% by mass or less, even more preferably 15% by mass or less, still more preferably 12% by mass or less, and even more preferably 11% by mass or less.
<12> The body patch sheet according to any one of <1> to <11>, wherein the mass ratio [(D)/(B)] in the gel layer is preferably 0.1 or more, more preferably 1 or more, even more preferably 2 or more, still more preferably 3 or more, and is preferably 7 or less, more preferably 6 or less, even more preferably 5 or less, and still more preferably 4 or less.
<13> The body patch sheet according to any one of <1> to <12>, wherein the layer consisting of the support and the gel layer has a bulk softness of preferably 0.20 or more, preferably 0.45 N or less, more preferably 0.40 N or less, and even more preferably 0.35 N or less.
<14> The body patch sheet according to any one of <1> to <13>, wherein the layer consisting of the support and the gel layer has a basis weight of preferably 1050 g/ ^m2 or more, more preferably 1100 g/ ^m2 or more, even more preferably 1150 g/ ^m2 or more, still more preferably 1200 g/ ^m2 or more, still more preferably 1250 g/ ^m2 or more, and is 2600 g/ ^m2 or less, preferably 2400 g/ ^m2 or less, more preferably 2200 g/ ^m2 or less, even more preferably 2100 g/ ^m2 or less, still more preferably 2000 g/ ^m2 or less, and still more preferably 1500 g/ ^m2 or less.
<15> The body application sheet according to any one of <1> to <14>, wherein the ball number of the gel layer in a ball tack test carried out in accordance with JIS Z0237:2009 under conditions of an inclined plate angle of 30°, a temperature of 23° C. and 50% R.H. is preferably 16 or more, more preferably 18 or more, and is preferably 28 or less, more preferably 26 or less, and even more preferably 23 or less.
<16> The body patch sheet according to any one of <1> to <15>, wherein the loss tangent of the gel layer, as measured by dynamic viscoelasticity at a temperature of 25°C and a frequency of 0.1 Hz, is preferably 0.15 or more, more preferably 0.20 or more, even more preferably 0.22 or more, still more preferably 0.25 or more, still more preferably 0.28 or more, and is preferably 0.70 or less, more preferably 0.60 or less, even more preferably 0.58 or less, still more preferably 0.50 or less, and still more preferably 0.35 or less.
<17> The body patch sheet according to any one of <1> to <16>, wherein the bulk softness in the MD direction of the support is preferably 0.15 N or more, more preferably 0.20 N or more, even more preferably 0.25 N or more, still more preferably 0.30 N or more, and is preferably 0.60 N or less, more preferably 0.50 N or less, even more preferably 0.45 N or less, still more preferably 0.38 N or less, and still more preferably 0.34 N or less.
<18> The body patch sheet according to any one of <1> to <17>, wherein the strength of the support at 50% elongation in the CD direction is preferably 0.3 N/5cm or more, more preferably 0.5 N/5cm or more, even more preferably 0.8 N/5cm or more, still more preferably 1.2 N/5cm or more, and is preferably 4.5 N/5cm or less, more preferably 4.0 N/5cm or less, even more preferably 3.5 N/5cm or less, still more preferably 3 N/5cm or less, still more preferably 2.5 N/5cm or less, and still more preferably less than 2 N/5cm.
<19> The body patch sheet according to any one of <1> to <18>, wherein the elongation recovery rate at 50% elongation in the CD direction of the support is preferably 50% or more, more preferably 55% or more, even more preferably 60% or more, still more preferably 70% or more, and is preferably 85% or less, more preferably 80% or less, even more preferably 75% or less.
<20> A sheet for application to the body having a support and a gel layer laminated on the support,
The gel layer is made of the following components (A), (B1) and (C1):
The gel-forming composition contains (A) water, (B1) a water-soluble polymer having a carboxy group and/or a salt thereof, and (C1) an aluminum-containing compound, and the content of the component (A) is 50% by mass or more and 85% by mass or less.
The layer consisting of the support and the gel layer has a bulk softness of 0.15 N or more and 0.50 N or less, and a basis weight of 1000 g/m ² or more and 2600 g/m ² or less,
The gel layer has a ball number of 14 or more and 30 or less in a ball tack test performed according to JIS Z0237:2009 under conditions of an inclined plate angle of 30°, a temperature of 23° C., and 50% R.H.
<21> The body patch sheet according to <20>, wherein the amount of component (C1) contained in the gel-forming composition is, in the gel-forming composition, preferably 0.005% by mass or more, more preferably 0.01% by mass or more, even more preferably 0.02% by mass or more, and is preferably 0.2% by mass or less, more preferably 0.1% by mass or less, even more preferably 0.06% by mass or less, and still more preferably 0.04% by mass or less.
<22> The body patch sheet according to <20> or <21>, wherein the content of component (B1) relative to the content of component (C1) (mass ratio [(B1)/(C1)]) is preferably 25 or more, more preferably 50 or more, even more preferably 60 or more, and is preferably 250 or less, more preferably 150 or less, even more preferably 120 or less, still more preferably 100 or less, and even more preferably 95 or less.
<23> The body patch sheet according to any one of <20> to <22>, wherein (C1) is at least one selected from the group consisting of aluminum hydroxide, aluminum magnesium hydroxide, sodium aluminate, aluminum sulfate, aluminum potassium sulfate, aluminum ammonium sulfate, aluminum carbonate, aluminum nitrate, aluminum chloride, magnesium alumino(meta)silicate, aluminum acetate, aluminum lactate, aluminum stearate, aluminum myristate, aluminum glycinate, aluminum benzoate, and aluminum allantoin chlorohydroxyl, more preferably magnesium alumino(meta)silicate, and still more preferably aluminum hydroxide and magnesium alumino(meta)silicate.
<24> A body application sheet according to any one of <1> to <23>, wherein the body application sheet has an outer shape in which the length in a first direction in a plan view is longer than the length in a second direction perpendicular to the first direction, and the CD direction of a support constituting the body application sheet is arranged to be the longitudinal direction of the body application sheet.
<25> A method for using a body application sheet according to any one of <1> to <24>, in which the body application sheet is applied so that the CD direction of the support constituting the body application sheet is the direction in which the body bends or rotates.

The present invention will be described below with reference to examples, but the present invention is not limited to the scope of the examples. The various measurements in the examples were performed according to the following methods.

Examples 1 to 9, Comparative Examples 1 to 5
(Preparation of gel-forming composition)
Gel-forming compositions were prepared according to the recipes shown in Tables 1 to 3. Specifically, a solution in which methyl paraoxybenzoate and menthol were dissolved in propylene glycol by heating, and an aqueous solution containing polyvinyl alcohol and a pH adjuster were prepared in advance. The aqueous solution containing polyvinyl alcohol and a pH adjuster was placed in a kneader, and then all other components were added and mixed to prepare a gel-forming composition. The blending amounts shown in Tables 1 to 3 are the active ingredient amounts (mass%) of each component.
(Manufacturing of body adhesive sheets)
The gel-forming composition was sandwiched between a nonwoven fabric support and a polypropylene release film under the conditions shown in Tables 1 to 3, and the thickness of the gel-forming composition layer was adjusted and spread using a Baker-type applicator to obtain a sheet in which the nonwoven fabric, the gel-forming composition layer, and the release film were laminated in this order. The nonwoven fabric shown in Table 4 was produced by a known method and used.
The sheet was cut into a rectangle of 12.5 cm x 8.5 cm so that the CD direction of the nonwoven fabric was the longitudinal direction of the sheet in a plan view, and was sealed in an aluminum pillow (120 mm x 170 mm, manufactured by AS ONE Corporation). The sheet was then aged under the conditions described in Tables 1 to 3 to promote the crosslinking reaction of the gel-forming composition layer, thereby producing a three-layered sheet for application to the body having, in that order, a nonwoven fabric, a gel layer, and a release film.
The obtained body patch sheet was evaluated by the following methods. The results are shown in Tables 1 to 3.

<Weight average molecular weight of component (D)>
The weight average molecular weight of the powder raw material of component (D) was determined by measuring an aqueous solution of the powder raw material dissolved in water by size exclusion chromatography (SEC) under the following conditions. The weight average molecular weight of component (D) in the gel layer was determined by measuring an extract of the gel layer by size exclusion chromatography (SEC) under the following conditions. The weight average molecular weight of component (D) shown in the table is the weight average molecular weight of component (D) in the powder raw material and the gel layer.
<SEC measurement conditions>
Measuring device: "SEC-8320" manufactured by Tosoh Corporation
Eluent: 0.2 mol/L phosphate buffer/acetonitrile = 9/1 (v/v%)
Guard column: "PWXL (6 mm x 4 cm)" manufactured by Tosoh Corporation
Analytical column: "G4000PWxL + G2500PWxL (7.8 mm x 30 cm)" manufactured by Tosoh Corporation
Flow rate: 1 mL/min
Column temperature: 40°C
Injection volume: 100 μL
Sample size: 1 mg/mL
Molecular weight conversion standard: PEO manufactured by Tosoh Corporation (SE-150 (977,000), SE-70 (580,000), SE-30 (394,000), SE-15 (143,000), SE-8 (101,000), SE-2 (21,000))
Detector: RI

<Method for measuring gel layer thickness>
The thickness of the gel layer was measured by the following method.
1. Thickness of Layer Composed of Support and Gel Layer First, the thickness of the center of the layer composed of the support and gel layer (hereinafter also referred to as support + gel) of each example of the body patch sheet was measured using a constant pressure thickness meter PG-11 (measuring probe diameter 35 mm, manufactured by Techclock Corporation).
2. Thickness of the Support Next, the gel was removed from the support + gel by alkali treatment, and after drying, only the support was taken out and the thickness of the support was measured using a constant pressure thickness measuring instrument PG-11 (manufactured by Techroc Corporation) in the same manner as in 1.
3. Thickness of Gel Layer The thickness of the gel layer was determined by subtracting the thickness of the support measured in 2 from the thickness of the support + gel measured in 1.
<Method of measuring bulk softness in layer consisting of support and gel layer>
The bulk softness measurement of the layer consisting of the support and the gel layer of each example of the body patch sheet was carried out under the conditions of 23 ° C. and 50% R.H. Each example of the body patch sheet was taken out of the aluminum pillow, and quickly cut out 80 mm in the longitudinal direction of the sheet and 20 mm in the width direction perpendicular to the longitudinal direction, and then the release film was peeled off, and the sheet was made into a ring shape with a diameter of about 25 mm with the support facing outward, and the longitudinal end of the sheet was fixed at two points, top and bottom, using a stapler. At this time, the longitudinal ends of the sheet were fixed so that they did not overlap and there was no gap (i.e., the longitudinal ends of the sheet were butted up against each other). The stapler core was oriented so that it was long in the longitudinal direction of the sheet (i.e., parallel to the longitudinal direction of the sheet), and fixed at two points, top and bottom, near both ends of the width direction of the sheet so as to straddle both ends of the longitudinal direction of the sheet. Using a tensile testing machine (Orientec Co., Ltd. tensile compression testing machine "STA-1150"), the ring was set up in a cylindrical shape in the center of a sample stage, and the maximum load was measured when compressing it from above with a flat plate having a diameter of about 60 mm that was approximately parallel to the stage at a compression rate of 10 mm/min, and this was taken as the bulk softness of the layer consisting of the gel layer and the support.
If the longitudinal length of the cut-out sheet (hereinafter also referred to as sheet piece) is less than 80 mm, a new sheet piece 20 mm wide cut out in the width direction perpendicular to the longitudinal direction of the sheet from the same body application sheet or from another body application sheet made by the same manufacturing method is stapled to the end of the insufficient sheet piece at two points above and below, and the bulk softness is then measured in the same manner as above.

<Method for measuring bulk softness in MD direction of support>
The bulk softness measurement of the support of each example was carried out under the conditions of 23°C and 50% R.H. The nonwoven fabric support was cut out to 150 mm in the CD direction and 30 mm in the MD direction, and the ends were stapled to a ring shape of about 45 mm in diameter at two points, top and bottom. At this time, both ends of the support in the CD direction were overlapped by 10 mm. The stapler core was made long in the CD direction of the nonwoven fabric (i.e., parallel to the CD direction of the support), and the center of the CD direction of the overlapping portion was fixed at two points, top and bottom, near both ends of the MD direction of the support. Using a tensile tester (Orientec Co., Ltd. tensile compression tester "STA-1150"), the ring was erected in a cylindrical shape in the center of the sample table, and compressed from above with a flat plate of about 60 mm in diameter almost parallel to the table at a compression speed of 10 mm/min. The maximum load was measured, and this was taken as the bulk softness of the support.

<Method for measuring strength of support at 50% elongation in CD direction>
The strength of the support at 50% elongation in the CD direction of each example was measured under the conditions of 23°C and 50% R.H. The nonwoven fabric support was cut out to a length of 150 mm in the CD direction and 50 mm in the MD direction, and the sample piece was fixed between both chucks (distance between chucks (grip interval)): 100 mm using a tensile tester (Tensilon manufactured by Orientec Co., Ltd.). Then, the chucks were separated at a tensile speed of 500 mm/min, and the maximum load measured until the sample piece was elongated by 50 mm was measured, and this was taken as the strength of the support at 50% elongation.

<Method for measuring elongation recovery rate at 50% elongation in CD direction of support>
The measurement of the elongation recovery rate at 50% elongation in the CD direction of each example of the support was carried out under the conditions of 23°C and 50% RH. A 150 mm long piece of nonwoven fabric as the support was cut out in the CD direction and 50 mm long in the MD direction, and the sample piece was fixed with a tensile tester (Tensilon manufactured by Orientec Co., Ltd.) between both chucks (distance between chucks (grip interval)): 100 mm. The position with the 100 mm grip interval was set as the starting point, and the sample was pulled at a speed of 500 mm/min to a position 50 mm from the starting point, i.e., to the 50% elongation position, and then returned to the starting point at the same speed. At this time, the length L0 is obtained by subtracting the length of the gripping interval when the tensile stress of the sample piece becomes 0.05 N when pulled from the length of the gripping interval at the 50% elongation position (150 mm), and the length L1 is obtained by subtracting the length of the gripping interval when the tensile stress of the sample piece becomes 0.05 N when returned from the length of the gripping interval at the 50% elongation position (150 mm). The numerical value calculated from the following formula is the recovery rate of the support at 50% elongation in the CD direction.
Elongation recovery rate (%) at 50% elongation = (L1/L0) x 100

<Ball tack test>
The ball tack test of the gel layer of the body application sheet of each example was carried out in accordance with JIS Z0237:2009 under the conditions of an inclined plate angle of 30°, a temperature of 23°C, and 50% R.H. The body application sheet of each example was removed from the aluminum pillow, the release film was peeled off, and then the sheet was quickly placed in a ball tack tester to carry out the ball tack test. The maximum ball number that stopped for 5 seconds or more in the adhesive region of the gel layer is shown in Tables 1 to 3.

<Loss tangent (tan δ)>
The loss tangent (tan δ) of the gel layer of each example of the body patch sheet was measured using a rheometer (Anton Paar Physica MCR301). Each example of the body patch sheet was cut into a circle with a diameter of 25 mm, and the nonwoven fabric side was fixed to the sample part of the rheometer (parallel plate with a diameter of 25 mm) with double-sided tape. The release film was then peeled off, and the loss modulus and storage modulus of the gel layer were measured under the following conditions, and the loss tangent (tan δ) was calculated from these values. The measurement was performed multiple times (three or more times), and the average value was used.
〔Measurement condition〕
・Normal force: 1N
・Gap distance: 1 to 2 mm
Mass of gel layer: 0.4 to 1.5 g
Measurement frequency: 0.1Hz
Distortion: 2%
Temperature: 25°C

<Motion tracking>
The body patch sheet of each example was taken out of the aluminum pillow, and immediately after peeling off the release film, it was applied to the side of the neck (right side of the neck) of the expert panelist so that the long side of the sheet was parallel to the circumference of the neck. 10 seconds after application, the expert panelist performed 10 neck rotations, and the area of the part of the body patch sheet that was floating from the neck, that is, the part that was peeled off from the neck, was measured. The ratio (%) of the area of the part where the sheet was peeled off to the entire area of the body patch sheet was calculated, and evaluated according to the following criteria. The higher the evaluation value, the better the adhesion immediately after application.
The evaluation by expert panelists in this example was carried out by three panelists in each case, and the evaluation values shown in the table are the average values of the three panelists.
〔Evaluation criteria〕
7: The area of peeled off sheet is 5% or less.
6: The percentage of the area of peeled off sheet is more than 5% and 10% or less.
5: The percentage of the area of the peeled off sheet is more than 10% and 20% or less.
4: The percentage of the area of peeled off sheet is more than 20% but not more than 30%.
3: The percentage of the area of peeled off sheet is more than 30% and 40% or less.
2: The percentage of the area of peeled off sheet is more than 40% and 50% or less.
1: The area ratio of the peeled off portion of the sheet is more than 50%.
In addition, it is practically preferable that the evaluation of the motion tracking ability is 4.0 or more.

<Sustained cooling effect>
Immediately after removing the body patch sheet of each example from the aluminum pillow and peeling off the release film, the sheet was applied to the lateral neck (right side of the neck) of a specialist panelist so that the long side of the sheet was parallel to the circumferential direction of the neck. After that, the panelist went about their daily life indoors, and the skin temperature was measured at five points a to e in the body patch sheet 1 in Figure 1 using a thermistor probe to determine the cooling effect 180 minutes after application. The skin temperature change ΔT (°C) was calculated using the following formula and evaluated as the average value of the five points measured.
Skin temperature change ΔT (°C) = (skin temperature 180 minutes after application of the body patch sheet) - (skin temperature before application of the body patch sheet)
The evaluation by expert panelists in this example was carried out by three panelists in each case, and the evaluation values shown in the table are the average values of the three panelists.
It is practically preferable that the cooling effect lasts for a period ΔT of −1.2° C. or less.

<Strain on the skin>
The body patch sheet of each example is taken out of the aluminum pillow, and immediately after peeling off the release film, the sheet is applied to the forearm of a specialist panelist so that the long side of the sheet is perpendicular to the circumferential direction of the forearm.When peeled off after 30 minutes from application, the burden on the skin is evaluated on a 5-point scale.In addition, the evaluation by the specialist panelists of this embodiment is performed by 3 panelists, and the evaluation values shown in the table are the average values of the 3 panelists.
〔Evaluation criteria〕
5: No strain on the skin.
4: It doesn't feel like much strain on the skin.
3: Somewhat harsh on the skin.
2: There is a slight feeling of strain on the skin.
1: I feel a burden on my skin.
In addition, it is practically preferable that the burden on the skin is evaluated to be 3.0 or more.

As seen from Tables 1 to 3, the body application sheet of this example, despite its high water content, has excellent movement-following ability even when applied to the neck, a part of the body that moves a lot, and therefore has excellent cooling effect durability. Also, as seen in Examples 1 and 3, even sheets that do not have a very high tack strength have excellent movement-following ability, good cooling effect durability, and can reduce the burden on the skin when the sheet is peeled off.
In contrast, the body application sheet of this comparative example was unable to satisfy both the requirements for movement followability and the durability of the cooling effect.

According to the present invention, a sheet with a high basis weight of hydrous gel can be provided that has high movement tracking ability, and has excellent durability of cooling effect, etc., even in areas with large and frequent movements, such as the neck, shoulders, and joints such as the knees, to be applied to the body.

Claims (5)

A sheet for application to the body having a support and a gel layer laminated on the support,
The gel layer comprises the following components (A) to (C):
(A) water; (B) a water-soluble polymer having a ^COO- group; (C) an aluminum atom-containing polymer;
The content of the component (A) in the gel layer is 50% by mass or more and 85% by mass or less,
The layer consisting of the support and the gel layer has a bulk softness of 0.15 N or more and 0.50 N or less, and a basis weight of 1000 g/m ² or more and 2600 g/m ² or less,
The gel layer has a ball number of 14 or more and 30 or less in a ball tack test performed according to JIS Z0237:2009 under conditions of an inclined plate angle of 30°, a temperature of 23° C., and 50% R.H. The body patch sheet according to claim 1, wherein the support is a nonwoven fabric. The body application sheet according to claim 1 or 2, wherein the strength of the support at 50% elongation in the CD direction is 0.5 N/5 cm or more and 4.0 N/5 cm or less. The body patch sheet according to any one of claims 1 to 3, further comprising polyvinyl alcohol (D). The body patch sheet according to any one of claims 1 to 4, wherein the mass ratio of said component (B) to said component (C) [(B)/(C)] is 200 or more and 800 or less.