JP2024001073A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2024001073A5 JP2024001073A5 JP2023165289A JP2023165289A JP2024001073A5 JP 2024001073 A5 JP2024001073 A5 JP 2024001073A5 JP 2023165289 A JP2023165289 A JP 2023165289A JP 2023165289 A JP2023165289 A JP 2023165289A JP 2024001073 A5 JP2024001073 A5 JP 2024001073A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- acid sequence
- seq
- antibody
- antigen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 125000003275 alpha amino acid group Chemical group 0.000 claims 28
- 239000012634 fragment Substances 0.000 claims 24
- 239000000427 antigen Substances 0.000 claims 23
- 102000036639 antigens Human genes 0.000 claims 23
- 108091007433 antigens Proteins 0.000 claims 23
- 101001133056 Homo sapiens Mucin-1 Proteins 0.000 claims 12
- 102100034256 Mucin-1 Human genes 0.000 claims 12
- 108010047041 Complementarity Determining Regions Proteins 0.000 claims 6
- 108010019670 Chimeric Antigen Receptors Proteins 0.000 claims 5
- 206010028980 Neoplasm Diseases 0.000 claims 5
- 201000011510 cancer Diseases 0.000 claims 5
- 210000004027 cell Anatomy 0.000 claims 5
- 108020004707 nucleic acids Proteins 0.000 claims 5
- 102000039446 nucleic acids Human genes 0.000 claims 5
- 150000007523 nucleic acids Chemical class 0.000 claims 5
- 230000004927 fusion Effects 0.000 claims 4
- 108020001507 fusion proteins Proteins 0.000 claims 4
- 102000037865 fusion proteins Human genes 0.000 claims 4
- 108090000765 processed proteins & peptides Proteins 0.000 claims 4
- 239000000611 antibody drug conjugate Substances 0.000 claims 3
- 229940049595 antibody-drug conjugate Drugs 0.000 claims 3
- 239000008194 pharmaceutical composition Substances 0.000 claims 3
- 108091026890 Coding region Proteins 0.000 claims 2
- 210000001744 T-lymphocyte Anatomy 0.000 claims 2
- 239000012472 biological sample Substances 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 206010006187 Breast cancer Diseases 0.000 claims 1
- 208000026310 Breast neoplasm Diseases 0.000 claims 1
- 206010009944 Colon cancer Diseases 0.000 claims 1
- 208000001333 Colorectal Neoplasms Diseases 0.000 claims 1
- 208000000461 Esophageal Neoplasms Diseases 0.000 claims 1
- 206010030155 Oesophageal carcinoma Diseases 0.000 claims 1
- 206010061902 Pancreatic neoplasm Diseases 0.000 claims 1
- 206010060862 Prostate cancer Diseases 0.000 claims 1
- 208000000236 Prostatic Neoplasms Diseases 0.000 claims 1
- 108010076504 Protein Sorting Signals Proteins 0.000 claims 1
- 210000004899 c-terminal region Anatomy 0.000 claims 1
- 229940127089 cytotoxic agent Drugs 0.000 claims 1
- 239000002254 cytotoxic agent Substances 0.000 claims 1
- 231100000599 cytotoxic agent Toxicity 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 201000004101 esophageal cancer Diseases 0.000 claims 1
- 208000015486 malignant pancreatic neoplasm Diseases 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 208000002154 non-small cell lung carcinoma Diseases 0.000 claims 1
- 201000002528 pancreatic cancer Diseases 0.000 claims 1
- 208000008443 pancreatic carcinoma Diseases 0.000 claims 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 1
- 230000011664 signaling Effects 0.000 claims 1
- 208000029729 tumor suppressor gene on chromosome 11 Diseases 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023165289A JP2024001073A (ja) | 2017-10-24 | 2023-09-27 | 抗グリコｍｕｃ１抗体およびその使用 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2020543460A JP7358367B2 (ja) | 2017-10-24 | 2017-10-24 | 抗グリコｍｕｃ１抗体およびその使用 |
| PCT/US2017/058036 WO2019083506A1 (en) | 2017-10-24 | 2017-10-24 | ANTI-GLYCO-MUC1 ANTIBODIES AND USES THEREOF |
| JP2023165289A JP2024001073A (ja) | 2017-10-24 | 2023-09-27 | 抗グリコｍｕｃ１抗体およびその使用 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020543460A Division JP7358367B2 (ja) | 2017-10-24 | 2017-10-24 | 抗グリコｍｕｃ１抗体およびその使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024001073A JP2024001073A (ja) | 2024-01-09 |
| JP2024001073A5 true JP2024001073A5 (da) | 2024-04-24 |
Family
ID=66247577
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020543460A Active JP7358367B2 (ja) | 2017-10-24 | 2017-10-24 | 抗グリコｍｕｃ１抗体およびその使用 |
| JP2023165289A Pending JP2024001073A (ja) | 2017-10-24 | 2023-09-27 | 抗グリコｍｕｃ１抗体およびその使用 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020543460A Active JP7358367B2 (ja) | 2017-10-24 | 2017-10-24 | 抗グリコｍｕｃ１抗体およびその使用 |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP3700936A4 (da) |
| JP (2) | JP7358367B2 (da) |
| KR (2) | KR102608763B1 (da) |
| CN (1) | CN111479828A (da) |
| AU (1) | AU2017436815A1 (da) |
| BR (1) | BR112020008001A2 (da) |
| CA (1) | CA3078812A1 (da) |
| IL (1) | IL274202A (da) |
| MX (1) | MX2020004220A (da) |
| WO (1) | WO2019083506A1 (da) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115068610B (zh) * | 2022-01-27 | 2024-04-16 | 中国农业大学 | 抑制乳腺癌细胞中muc1表达的物质在降低抗乳腺癌药物耐药性中的应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2001249760B2 (en) * | 2000-03-30 | 2005-04-21 | Dyax Corp. | Mucin-1 specific binding members and methods of use thereof |
| DE10303664A1 (de) * | 2003-01-23 | 2004-08-12 | Nemod Immuntherapie Ag | Erkennungsmoleküle zur Behandlung und Detektion von Tumoren |
| EP2014302A1 (en) * | 2007-07-12 | 2009-01-14 | Institut Curie | An antibody specific for the Tn antigen for the treatment of cancer |
| CA2707689A1 (en) * | 2007-12-05 | 2009-06-11 | Kyowa Hakko Kirin Co., Ltd. | Monoclonal antibody capable of binding to heparin-binding epidermal growth factor-like growth factor |
| CA2741798A1 (en) * | 2008-10-28 | 2010-05-06 | Shionogi & Co., Ltd. | Anti-muc1 antibody |
| EP2281844A1 (en) * | 2009-07-31 | 2011-02-09 | Glycotope GmbH | MUC 1 antibodies |
| US10208125B2 (en) * | 2013-07-15 | 2019-02-19 | University of Pittsburgh—of the Commonwealth System of Higher Education | Anti-mucin 1 binding agents and uses thereof |
| AU2015254257B2 (en) * | 2014-04-28 | 2021-02-25 | Medicinal Chemistry Pharmaceuticals, Co., Ltd. | Anti-MUC1 antibody or antigen-binding fragment of same, and use thereof |
-
2017
- 2017-10-24 JP JP2020543460A patent/JP7358367B2/ja active Active
- 2017-10-24 EP EP17929557.1A patent/EP3700936A4/en active Pending
- 2017-10-24 MX MX2020004220A patent/MX2020004220A/es unknown
- 2017-10-24 CA CA3078812A patent/CA3078812A1/en active Pending
- 2017-10-24 WO PCT/US2017/058036 patent/WO2019083506A1/en unknown
- 2017-10-24 BR BR112020008001-2A patent/BR112020008001A2/pt unknown
- 2017-10-24 CN CN201780097773.8A patent/CN111479828A/zh active Pending
- 2017-10-24 KR KR1020207014390A patent/KR102608763B1/ko active IP Right Grant
- 2017-10-24 KR KR1020237040745A patent/KR20230165874A/ko active Application Filing
- 2017-10-24 AU AU2017436815A patent/AU2017436815A1/en active Pending
-
2020
- 2020-04-23 IL IL274202A patent/IL274202A/en unknown
-
2023
- 2023-09-27 JP JP2023165289A patent/JP2024001073A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP3353213B1 (en) | Anti-mesothelin antibody and composition comprising the same | |
| JP7150880B2 (ja) | 抗－ｂ７－ｈ３抗体およびその用途 | |
| JP2019116474A5 (da) | ||
| US20190367612A1 (en) | Anti-gprc5d antibody and molecule containing same | |
| EP4039707A1 (en) | Cd3-targeting antibody, bispecific antibody and use thereof | |
| JP2019527553A5 (da) | ||
| JP2013502913A5 (da) | ||
| JP2021503455A5 (da) | ||
| AU2020352382A1 (en) | Anti-human claudin 18.2 antibody and application thereof | |
| TWI805121B (zh) | 抗ＳＩＲＰα抗體及其用途 | |
| KR20160127825A (ko) | 항-mcam 항체 및 관련된 사용 방법 | |
| AU2017379382A1 (en) | Anti-CD3 Antibody and Molecules Comprising the Antibody | |
| EP4155320A1 (en) | Anti-b7h4 antibody, and bispecific antibody and use thereof | |
| JP2010509931A (ja) | 新規抗増殖性化合物 | |
| US20230391882A1 (en) | Combination treatment | |
| JP2020522488A5 (da) | ||
| JP2018522888A5 (da) | ||
| KR20220111308A (ko) | 인간화 cldn18.2 항체 | |
| JP2024001073A5 (da) | ||
| CN113574069A (zh) | 抗pd-l1抗体及其用途 | |
| TW202241944A (zh) | 新穎的抗ｇｒｅｍｌｉｎ１抗體 | |
| JPWO2020114480A5 (da) | ||
| JPWO2019185040A5 (da) | ||
| TW202300529A (zh) | 特定性增強雙專一性抗體 | |
| CN115776897A (zh) | 具有H2L2与HCAb结构的结合蛋白 |