JP2023554500A5 - - Google Patents

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Publication number
JP2023554500A5
JP2023554500A5 JP2023537572A JP2023537572A JP2023554500A5 JP 2023554500 A5 JP2023554500 A5 JP 2023554500A5 JP 2023537572 A JP2023537572 A JP 2023537572A JP 2023537572 A JP2023537572 A JP 2023537572A JP 2023554500 A5 JP2023554500 A5 JP 2023554500A5
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JP
Japan
Prior art keywords
seq
heavy chain
chain monomer
amino acid
acid sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2023537572A
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English (en)
Japanese (ja)
Other versions
JP7778148B2 (ja
JP2023554500A (ja
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Priority claimed from PCT/IB2021/061972 external-priority patent/WO2022130342A1/en
Publication of JP2023554500A publication Critical patent/JP2023554500A/ja
Publication of JP2023554500A5 publication Critical patent/JP2023554500A5/ja
Priority to JP2025197132A priority Critical patent/JP2026041774A/ja
Application granted granted Critical
Publication of JP7778148B2 publication Critical patent/JP7778148B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2023537572A 2020-12-18 2021-12-17 四価FZD及びWNTコレセプター(co-receptor)結合抗体分子並びにその使用 Active JP7778148B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025197132A JP2026041774A (ja) 2020-12-18 2025-11-18 四価FZD及びWNTコレセプター(co-receptor)結合抗体分子並びにその使用

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063127408P 2020-12-18 2020-12-18
US63/127,408 2020-12-18
PCT/IB2021/061972 WO2022130342A1 (en) 2020-12-18 2021-12-17 Tetravalent fzd and wnt co-receptor binding antibody molecules and uses thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025197132A Division JP2026041774A (ja) 2020-12-18 2025-11-18 四価FZD及びWNTコレセプター(co-receptor)結合抗体分子並びにその使用

Publications (3)

Publication Number Publication Date
JP2023554500A JP2023554500A (ja) 2023-12-27
JP2023554500A5 true JP2023554500A5 (OSRAM) 2025-05-20
JP7778148B2 JP7778148B2 (ja) 2025-12-01

Family

ID=82058983

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2023537572A Active JP7778148B2 (ja) 2020-12-18 2021-12-17 四価FZD及びWNTコレセプター(co-receptor)結合抗体分子並びにその使用
JP2023537540A Pending JP2024500839A (ja) 2020-12-18 2021-12-17 四価FZD及びWNTコレセプター(co-receptor)結合抗体分子並びにその使用
JP2025197132A Pending JP2026041774A (ja) 2020-12-18 2025-11-18 四価FZD及びWNTコレセプター(co-receptor)結合抗体分子並びにその使用

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2023537540A Pending JP2024500839A (ja) 2020-12-18 2021-12-17 四価FZD及びWNTコレセプター(co-receptor)結合抗体分子並びにその使用
JP2025197132A Pending JP2026041774A (ja) 2020-12-18 2025-11-18 四価FZD及びWNTコレセプター(co-receptor)結合抗体分子並びにその使用

Country Status (11)

Country Link
US (3) US20250270332A1 (OSRAM)
EP (3) EP4263618A4 (OSRAM)
JP (3) JP7778148B2 (OSRAM)
KR (1) KR20230122077A (OSRAM)
CN (2) CN116917332A (OSRAM)
AU (2) AU2021404080A1 (OSRAM)
CA (2) CA3204322A1 (OSRAM)
CL (2) CL2023001768A1 (OSRAM)
IL (2) IL303342A (OSRAM)
MX (1) MX2023007103A (OSRAM)
WO (2) WO2022130342A1 (OSRAM)

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US11773171B2 (en) 2017-12-19 2023-10-03 Surrozen Operating, Inc. WNT surrogate molecules and uses thereof
CA3140580A1 (en) * 2019-06-11 2020-12-17 Antlera Therapeutics Inc. Multivalent fzd and wnt binding molecules and uses thereof
WO2023250402A2 (en) * 2022-06-22 2023-12-28 Antlera Therapeutics Inc. Tetravalent fzd and wnt co-receptor binding antibody molecules and uses thereof
CA3238967A1 (en) * 2021-12-31 2023-07-06 Surrozen Operating, Inc. Wnt receptor-specific compound and method relating thereto
EP4547713A2 (en) * 2022-06-30 2025-05-07 The University of Chicago Cd73 (nt5e) targeting polypeptides
EP4705355A1 (en) * 2023-04-27 2026-03-11 Surrozen Operating, Inc. Molecules modulating wnt signaling pathways and uses thereof
WO2025019458A2 (en) * 2023-07-14 2025-01-23 The Trustees Of Columbia University In The City Of New York Specific blood retinal barrier defect in glaucoma directs new treatments and clinical tests
WO2025168716A1 (en) 2024-02-07 2025-08-14 Eyebiotech Limited Compositions, doses, and methods for treatment of ocular diseases
WO2025176847A1 (en) 2024-02-21 2025-08-28 Ags Therapeutics Sas Ocular delivery of active agents via microalgae extracellular vesicles
US20260092109A1 (en) * 2024-09-06 2026-04-02 Eyebiotech Limited Multivalent fzd4, wnt co-receptor, and vegf receptor molecules and uses thereof
US20260092125A1 (en) * 2024-09-06 2026-04-02 Eyebiotech Limited Multivalent fzd4, wnt co-receptor, and vegf binding molecules and uses thereof

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ES2113940T3 (es) 1990-12-03 1998-05-16 Genentech Inc Metodo de enriquecimiento para variantes de proteinas con propiedades de union alteradas.
EP1240319A1 (en) 1999-12-15 2002-09-18 Genentech, Inc. Shotgun scanning, a combinatorial method for mapping functional protein epitopes
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US20050079574A1 (en) 2003-01-16 2005-04-14 Genentech, Inc. Synthetic antibody phage libraries
US7785903B2 (en) 2004-04-09 2010-08-31 Genentech, Inc. Variable domain library and uses
EP1957531B1 (en) 2005-11-07 2016-04-13 Genentech, Inc. Binding polypeptides with diversified and consensus vh/vl hypervariable sequences
WO2007064919A2 (en) 2005-12-02 2007-06-07 Genentech, Inc. Binding polypeptides with restricted diversity sequences
CA2651567A1 (en) 2006-05-09 2007-11-22 Genentech, Inc. Binding polypeptides with optimized scaffolds
CN100592373C (zh) 2007-05-25 2010-02-24 群康科技(深圳)有限公司 液晶显示面板驱动装置及其驱动方法
TWI506037B (zh) 2008-09-26 2015-11-01 Oncomed Pharm Inc 捲曲結合劑類及彼等之用途
US9200072B2 (en) 2012-01-18 2015-12-01 Genentech Inc. Anti-LRP5 antibodies and methods of use
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AU2014246658B2 (en) 2013-04-03 2018-10-04 Peter Maccallum Cancer Institute Antibodies against human RYK and uses therefor
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CA2921398C (en) 2013-08-14 2021-12-14 The Governing Council Of The University Of Toronto Antibodies for inhibiting frizzled receptors and pharmaceutical compositions containing antibodies for inhibiting frizzled receptors
AR103442A1 (es) 2015-01-16 2017-05-10 Juno Therapeutics Inc Anticuerpos y receptores de antígenos quiméricos específicos de ror1
CA3012720C (en) 2016-01-29 2023-01-31 The Governing Council Of The University Of Toronto Frizzled5 protein-binding agents
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US11039659B2 (en) 2017-09-07 2021-06-22 Nike, Inc. Sole structure for article of footwear
US20210032352A1 (en) 2018-02-14 2021-02-04 Antera Therapeutics Inc. Multivalent Binding Molecules Activating WNT Signaling and Uses Thereof
EP3820906B1 (en) * 2018-07-05 2025-10-15 Surrozen Operating, Inc. Multi-specific wnt surrogate molecules and uses thereof
US10671121B2 (en) 2018-09-14 2020-06-02 Apple Inc. Magnetic layout in electronic devices and accessory devices for electronic devices
CA3140580A1 (en) * 2019-06-11 2020-12-17 Antlera Therapeutics Inc. Multivalent fzd and wnt binding molecules and uses thereof

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