JP2023548508A - ヒドロゲル組成物及びその使用方法 - Google Patents

ヒドロゲル組成物及びその使用方法 Download PDF

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JP2023548508A
JP2023548508A JP2023526661A JP2023526661A JP2023548508A JP 2023548508 A JP2023548508 A JP 2023548508A JP 2023526661 A JP2023526661 A JP 2023526661A JP 2023526661 A JP2023526661 A JP 2023526661A JP 2023548508 A JP2023548508 A JP 2023548508A
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cells
matrix
elp
cell
hydrogel
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Japanese (ja)
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JP2023548508A5 (https=
Inventor
ハイルスホルン，サラ
ソハール，ライリー
ハント，ダニエル
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Leland Stanford Junior University
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Leland Stanford Junior University
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0679—Cells of the gastro-intestinal tract
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068—General culture methods using substrates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0062—General methods for three-dimensional culture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0012—Cell encapsulation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/90—Polysaccharides
    • C12N2501/905—Hyaluronic acid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/998—Proteins not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2509/00—Methods for the dissociation of cells, e.g. specific use of enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2513/00—3D culture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/70—Polysaccharides
    • C12N2533/80—Hyaluronan
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2537/00—Supports and/or coatings for cell culture characterised by physical or chemical treatment
    • C12N2537/10—Cross-linking

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
JP2023526661A 2020-11-06 2021-11-03 ヒドロゲル組成物及びその使用方法 Pending JP2023548508A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063110667P 2020-11-06 2020-11-06
US63/110,667 2020-11-06
PCT/US2021/057925 WO2022098777A1 (en) 2020-11-06 2021-11-03 Hydrogel compositions and methods of use thereof

Publications (2)

Publication Number Publication Date
JP2023548508A true JP2023548508A (ja) 2023-11-17
JP2023548508A5 JP2023548508A5 (https=) 2024-11-11

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JP2023526661A Pending JP2023548508A (ja) 2020-11-06 2021-11-03 ヒドロゲル組成物及びその使用方法

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US (1) US20230365940A1 (https=)
EP (1) EP4240327A4 (https=)
JP (1) JP2023548508A (https=)
KR (1) KR20230104219A (https=)
CN (1) CN116829126A (https=)
AU (1) AU2021376143A1 (https=)
CA (1) CA3196621A1 (https=)
IL (1) IL302453A (https=)
WO (1) WO2022098777A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI131721B1 (en) * 2023-09-20 2025-10-16 Teknologian Tutkimuskeskus Vtt Oy Structural protein, medical product, electrospun filament, photonic crystals, metamaterial, thermosensitive glass and method for manufacturing a product
WO2026015902A1 (en) * 2024-07-12 2026-01-15 The Regents Of The University Of California Synthetic matrix for stem cell encapsulation

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20200038484A1 (en) * 2017-02-06 2020-02-06 The Board Of Trustees Of The Leland Stanford Junior University Bioconjugation Methods for Targeted in Situ Therapeutic Delivery

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009022339A1 (en) * 2007-08-15 2009-02-19 Ramot At Tel Aviv University Ltd. Polypeptides, matrices, hydrogels and methods of using same for tissue regeneration and repair
KR20130047404A (ko) * 2011-10-31 2013-05-08 재단법인대구경북과학기술원 엘라스틴 유사 인공 세포외 기질을 이용한 3차원 세포 군집체의 형성 방법과 이를 기반으로 마련된 3차원 세포 군집체

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20200038484A1 (en) * 2017-02-06 2020-02-06 The Board Of Trustees Of The Leland Stanford Junior University Bioconjugation Methods for Targeted in Situ Therapeutic Delivery

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
BENJAMIN M. RICHARDSON ET AL.: "Hydrazone covalent adaptable networks modulate extracellular matrix deposition for cartilage tissue", ACTA BIOMATERIALIA, vol. 83, JPN6025052512, January 2019 (2019-01-01), pages 71 - 82, ISSN: 0005760161 *
DANQING ZHU ET AL.: "Elastin-like protein-hyaluronic acid (ELP-HA) hydrogels with decoupled mechanical and biochemical cu", BIOMATERIALS, vol. 127, JPN6025052514, May 2017 (2017-05-01), pages 132 - 140, ISSN: 0005760158 *
JUNZHE LOU ET AL: "Stress relaxing hyaluronic acid-collagen hydrogels promote cell spreading, fiber remodeling, and foc", BIOMATERIALS, vol. 154, JPN6025052513, February 2018 (2018-02-01), pages 213 - 222, ISSN: 0005760160 *
STEVEN R CALIARI ET AL.: "A practical guide to hydrogels for cell culture", NATURE METHODS, vol. 13, no. 5, JPN6025052511, 28 April 2016 (2016-04-28), pages 405 - 414, ISSN: 0005760159 *

Also Published As

Publication number Publication date
WO2022098777A1 (en) 2022-05-12
IL302453A (en) 2023-06-01
CA3196621A1 (en) 2022-05-12
AU2021376143A1 (en) 2023-06-08
US20230365940A1 (en) 2023-11-16
KR20230104219A (ko) 2023-07-07
EP4240327A1 (en) 2023-09-13
CN116829126A (zh) 2023-09-29
EP4240327A4 (en) 2025-03-05

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