JP2023545403A5 - - Google Patents

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Publication number
JP2023545403A5
JP2023545403A5 JP2023520242A JP2023520242A JP2023545403A5 JP 2023545403 A5 JP2023545403 A5 JP 2023545403A5 JP 2023520242 A JP2023520242 A JP 2023520242A JP 2023520242 A JP2023520242 A JP 2023520242A JP 2023545403 A5 JP2023545403 A5 JP 2023545403A5
Authority
JP
Japan
Prior art keywords
guide rna
cells
target site
nucleotides
cleavage
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023520242A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023545403A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2021/077206 external-priority patent/WO2022069756A1/en
Publication of JP2023545403A publication Critical patent/JP2023545403A/ja
Publication of JP2023545403A5 publication Critical patent/JP2023545403A5/ja
Pending legal-status Critical Current

Links

JP2023520242A 2020-10-02 2021-10-01 Ｃｒｉｓｐｒを介した指令コドン書換え Pending JP2023545403A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP20306150 2020-10-02
EP20306150.2 2020-10-02
PCT/EP2021/077206 WO2022069756A1 (en) 2020-10-02 2021-10-01 Crispr-mediated directed codon re-write

Publications (2)

Publication Number Publication Date
JP2023545403A JP2023545403A (ja) 2023-10-30
JP2023545403A5 true JP2023545403A5 (https=) 2024-10-09

Family

ID=78087338

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023520242A Pending JP2023545403A (ja) 2020-10-02 2021-10-01 Ｃｒｉｓｐｒを介した指令コドン書換え

Country Status (4)

Country Link
US (1) US20230348874A1 (https=)
EP (1) EP4222256A1 (https=)
JP (1) JP2023545403A (https=)
WO (1) WO2022069756A1 (https=)

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2013266968B2 (en) 2012-05-25 2017-06-29 Emmanuelle CHARPENTIER Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription
US8697359B1 (en) 2012-12-12 2014-04-15 The Broad Institute, Inc. CRISPR-Cas systems and methods for altering expression of gene products
US20180291372A1 (en) * 2015-05-14 2018-10-11 Massachusetts Institute Of Technology Self-targeting genome editing system
BR112018008134A2 (pt) * 2015-10-20 2018-11-06 Pioneer Hi Bred Int método para restaurar a função de um produto gênico não funcional no genoma de uma célula, método para editar uma sequência nucleotídica no genoma de uma célula, planta ou planta de progênie, método para editar uma sequência nucleotídica no genoma de uma célula sem o uso de um molde polinucleotídico de modificação e método para entregar um complexo de rna guia/endonuclease cas numa célula
JP7816916B2 (ja) * 2017-09-08 2026-02-18 キージーン ナムローゼ フェンノートシャップ バランスがとれたインデル
CA3097963A1 (en) * 2018-05-07 2019-11-14 Pioneer Hi-Bred International, Inc. Methods and compositions for homology-directed repair of cas endonuclease mediated double strand breaks
CN113728106A (zh) * 2019-03-08 2021-11-30 齐默尔根公司 微生物中的迭代基因组编辑
WO2020191233A1 (en) * 2019-03-19 2020-09-24 The Broad Institute, Inc. Methods and compositions for editing nucleotide sequences

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