JP2023543978A5 - - Google Patents

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Publication number
JP2023543978A5
JP2023543978A5 JP2023516587A JP2023516587A JP2023543978A5 JP 2023543978 A5 JP2023543978 A5 JP 2023543978A5 JP 2023516587 A JP2023516587 A JP 2023516587A JP 2023516587 A JP2023516587 A JP 2023516587A JP 2023543978 A5 JP2023543978 A5 JP 2023543978A5
Authority
JP
Japan
Prior art keywords
pharmaceutical composition
composition according
antagonist
heavy chain
light chain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023516587A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023543978A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/050143 external-priority patent/WO2022060678A1/en
Publication of JP2023543978A publication Critical patent/JP2023543978A/ja
Publication of JP2023543978A5 publication Critical patent/JP2023543978A5/ja
Pending legal-status Critical Current

Links

JP2023516587A 2020-09-15 2021-09-14 がん患者を治療するためのpd-1拮抗薬及びlag3拮抗薬及びレンバチニブ又はそれの薬学的に許容される塩の併用療法 Pending JP2023543978A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063078485P 2020-09-15 2020-09-15
US63/078,485 2020-09-15
PCT/US2021/050143 WO2022060678A1 (en) 2020-09-15 2021-09-14 Combination therapy of a pd-1 antagonist and lag3 antagonist and lenvatinib or a pharmaceutically acceptable salt thereof for treating patients with cancer

Publications (2)

Publication Number Publication Date
JP2023543978A JP2023543978A (ja) 2023-10-19
JP2023543978A5 true JP2023543978A5 (https=) 2024-09-25

Family

ID=80777346

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023516587A Pending JP2023543978A (ja) 2020-09-15 2021-09-14 がん患者を治療するためのpd-1拮抗薬及びlag3拮抗薬及びレンバチニブ又はそれの薬学的に許容される塩の併用療法

Country Status (9)

Country Link
US (1) US20240010729A1 (https=)
EP (1) EP4213846A4 (https=)
JP (1) JP2023543978A (https=)
KR (1) KR20230069957A (https=)
CN (1) CN116457016A (https=)
AU (1) AU2021344849A1 (https=)
CA (1) CA3195058A1 (https=)
MX (1) MX2023003032A (https=)
WO (1) WO2022060678A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20250064794A1 (en) * 2021-08-10 2025-02-27 Eisai R&D Management Co., Ltd. A therapeutic combination comprising a tigit antagonist, a pd-1 antagonist, and lenvatinib
TW202509063A (zh) * 2023-08-21 2025-03-01 瑞士商百濟神州瑞士有限責任公司 用抗lag3、抗pd-1和化學療法治療食管癌

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102662228B1 (ko) * 2015-03-04 2024-05-02 머크 샤프 앤드 돔 코포레이션 암을 치료하기 위한 pd-1 길항제 및 vegfr/fgfr/ret 티로신 키나제 억제제의 조합
WO2017079746A2 (en) * 2015-11-07 2017-05-11 Multivir Inc. Methods and compositions comprising tumor suppressor gene therapy and immune checkpoint blockade for the treatment of cancer
US11045547B2 (en) * 2015-12-16 2021-06-29 Merck Sharp & Dohme Corp. Anti-LAG3 antibodies and antigen-binding fragments
EP3793557A1 (en) * 2018-05-14 2021-03-24 Merck Sharp & Dohme Corp. Biomarkers for a combination therapy comprising lenvatinib and a pd-1 antagonist
CN112839652A (zh) * 2018-08-15 2021-05-25 艾葳生物科技有限公司 VEGF和TGFβ的多激酶抑制剂及其用途
EP3880709A4 (en) * 2018-11-05 2022-07-27 Merck Sharp & Dohme Corp. DOSING REGIME OF ANTI-LAG3 ANTIBODIES AND COMBINATION THERAPY WITH ANTI-PD-1 ANTIBODIES FOR THE TREATMENT OF CANCER
EP3876990A4 (en) * 2018-11-07 2023-09-06 Merck Sharp & Dohme LLC CO-FORMULATIONS OF ANTI-LAG3 ANTIBODIES AND ANTI-PD-1 ANTIBODIES
US20230118596A1 (en) * 2020-03-05 2023-04-20 Merck Sharp & Dohme Llc Methods for treating cancer using a combination of a pd-1 antagonist, a ctla4 antagonist, and lenvatinib or a pharmaceutically accpetable salt thereof

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