JP2023542608A5 - - Google Patents

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Publication number
JP2023542608A5
JP2023542608A5 JP2023507542A JP2023507542A JP2023542608A5 JP 2023542608 A5 JP2023542608 A5 JP 2023542608A5 JP 2023507542 A JP2023507542 A JP 2023507542A JP 2023507542 A JP2023507542 A JP 2023507542A JP 2023542608 A5 JP2023542608 A5 JP 2023542608A5
Authority
JP
Japan
Prior art keywords
prostate cancer
subject
antagonist
composition according
glucocorticoid receptor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023507542A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023542608A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/044255 external-priority patent/WO2022031642A2/en
Publication of JP2023542608A publication Critical patent/JP2023542608A/ja
Publication of JP2023542608A5 publication Critical patent/JP2023542608A5/ja
Pending legal-status Critical Current

Links

JP2023507542A 2020-08-04 2021-08-03 グルココルチコイド受容体(gr)アンタゴニストおよびアンドロゲン受容体(ar)分解誘導剤の組み合わせの使用 Pending JP2023542608A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202063061013P 2020-08-04 2020-08-04
US63/061,013 2020-08-04
US202163226102P 2021-07-27 2021-07-27
US63/226,102 2021-07-27
PCT/US2021/044255 WO2022031642A2 (en) 2020-08-04 2021-08-03 Uses of glucocorticoid receptor (gr) antagonist and androgen receptor (ar) degrader combinations

Publications (2)

Publication Number Publication Date
JP2023542608A JP2023542608A (ja) 2023-10-11
JP2023542608A5 true JP2023542608A5 (https=) 2024-07-30

Family

ID=80118471

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023507542A Pending JP2023542608A (ja) 2020-08-04 2021-08-03 グルココルチコイド受容体(gr)アンタゴニストおよびアンドロゲン受容体(ar)分解誘導剤の組み合わせの使用

Country Status (5)

Country Link
US (1) US20230302014A1 (https=)
EP (1) EP4192460A4 (https=)
JP (1) JP2023542608A (https=)
CN (1) CN116322694A (https=)
WO (1) WO2022031642A2 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12226412B2 (en) 2012-05-25 2025-02-18 Corcept Therapeutics, Inc. Heteroaryl-ketone fused azadecalin glucocorticoid receptor modulators
US11285145B2 (en) 2020-05-27 2022-03-29 Corcept Therapeutics Incorporated Concomitant administration of glucocorticoid receptor modulator relacorilant and paclitaxel, a dual substrate of CYP2C8 and CYP3A4
WO2024006527A1 (en) * 2022-07-01 2024-01-04 Arvinas Operations, Inc. Breast cancer treatment method
JP2025530798A (ja) * 2022-09-02 2025-09-17 コーセプト セラピューティクス, インコーポレイテッド エキシコリラントとエンザルタミドを用いて前立腺がんを治療する方法
WO2024092195A1 (en) * 2022-10-28 2024-05-02 Corcept Therapeutics Incorporated Treatments for amyotrophic lateral sclerosis using dazucorilant
WO2024220926A1 (en) * 2023-04-21 2024-10-24 Arvinas Operations, Inc. Use of an androgen receptor degrader protac for the treatment of prostate cancer
WO2024233696A1 (en) * 2023-05-09 2024-11-14 Arvinas Operations, Inc. Bavdegalutamide for treating prostate cancer without ar l702h mutation
TW202535392A (zh) 2023-12-08 2025-09-16 美商亞文納營運公司 使用雄性素受體降解劑治療脊髓延髓性肌肉萎縮

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108699102A (zh) * 2015-12-23 2018-10-23 欧瑞克制药公司 糖皮质激素受体抑制剂
CN110506039A (zh) * 2016-10-11 2019-11-26 阿尔维纳斯股份有限公司 用于雄激素受体靶向降解的化合物和方法
EP3793541A4 (en) * 2018-05-16 2022-03-02 GTx, Inc. ANDROGEN RECEPTOR DEGRADER (SARD) SELECTIVE LIGANDS AND METHODS OF USE THEREOF

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