JP2023539341A5 - - Google Patents

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Publication number
JP2023539341A5
JP2023539341A5 JP2023514067A JP2023514067A JP2023539341A5 JP 2023539341 A5 JP2023539341 A5 JP 2023539341A5 JP 2023514067 A JP2023514067 A JP 2023514067A JP 2023514067 A JP2023514067 A JP 2023514067A JP 2023539341 A5 JP2023539341 A5 JP 2023539341A5
Authority
JP
Japan
Application number
JP2023514067A
Other languages
Japanese (ja)
Other versions
JP2023539341A (ja
JPWO2022051332A5 (https=
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/048611 external-priority patent/WO2022051332A1/en
Publication of JP2023539341A publication Critical patent/JP2023539341A/ja
Publication of JP2023539341A5 publication Critical patent/JP2023539341A5/ja
Publication of JPWO2022051332A5 publication Critical patent/JPWO2022051332A5/ja
Pending legal-status Critical Current

Links

JP2023514067A 2020-09-01 2021-09-01 Dux4阻害剤およびその使用方法 Pending JP2023539341A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063073304P 2020-09-01 2020-09-01
US63/073,304 2020-09-01
PCT/US2021/048611 WO2022051332A1 (en) 2020-09-01 2021-09-01 Dux4 inhibitors and methods of use thereof

Publications (3)

Publication Number Publication Date
JP2023539341A JP2023539341A (ja) 2023-09-13
JP2023539341A5 true JP2023539341A5 (https=) 2024-08-23
JPWO2022051332A5 JPWO2022051332A5 (https=) 2024-08-23

Family

ID=80492176

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023514067A Pending JP2023539341A (ja) 2020-09-01 2021-09-01 Dux4阻害剤およびその使用方法

Country Status (8)

Country Link
US (1) US20230348906A1 (https=)
EP (1) EP4208548A4 (https=)
JP (1) JP2023539341A (https=)
AR (1) AR123420A1 (https=)
AU (1) AU2021337595A1 (https=)
CA (1) CA3189861A1 (https=)
TW (1) TW202227626A (https=)
WO (1) WO2022051332A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12018087B2 (en) 2018-08-02 2024-06-25 Dyne Therapeutics, Inc. Muscle-targeting complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and methods of delivering oligonucleotide to a subject
US20220193250A1 (en) 2018-08-02 2022-06-23 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy
US11555190B2 (en) 2020-03-19 2023-01-17 Avidity Biosciences, Inc. Compositions and methods of treating Facioscapulohumeral muscular dystrophy
CA3174286A1 (en) 2020-04-02 2021-10-07 Robert PLACE Targeted inhibition using engineered oligonucleotides
IL301187A (en) 2020-09-11 2023-05-01 Arrowhead Pharmaceuticals Inc RNAi agents for suppressing DUX4 expression, preparations containing them and uses thereof
US11638761B2 (en) 2021-07-09 2023-05-02 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating Facioscapulohumeral muscular dystrophy
US11969475B2 (en) 2021-07-09 2024-04-30 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy
MX2024003266A (es) 2021-09-16 2024-04-03 Avidity Biosciences Inc Composiciones y metodos de tratamiento de la distrofia muscular facioescapulohumeral.
WO2023185946A1 (zh) * 2022-03-30 2023-10-05 苏州瑞博生物技术股份有限公司 一种寡核苷酸缀合物、含有该寡核苷酸缀合物的组合物及制备方法和用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2305812A3 (en) * 2002-11-14 2012-06-06 Dharmacon, Inc. Fuctional and hyperfunctional sirna
WO2012024535A2 (en) * 2010-08-18 2012-02-23 Fred Hutchinson Cancer Research Center Methods for determining the presence or risk of developing facioscapulohumeral dystrophy (fshd)
AU2012286994B2 (en) * 2011-07-25 2017-08-10 Nationwide Children's Hospital, Inc. Recombinant virus products and methods for inhibition of expression of DUX4
US10538763B2 (en) * 2015-01-16 2020-01-21 Ionis Pharmaceuticals, Inc. Compounds and methods for modulation of DUX4
AU2018345772B2 (en) * 2017-10-02 2025-04-17 Research Institute At Nationwide Children's Hospital MiRNA detargeting system for tissue specific interference
IL279102B2 (en) * 2018-05-30 2024-10-01 Dtx Pharma Inc Lipid-modified nucleic acid compounds and methods
WO2020028134A1 (en) * 2018-07-30 2020-02-06 Fred Hutchinson Cancer Research Center Methods and compositions for treating cancer
US20220193250A1 (en) * 2018-08-02 2022-06-23 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy

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