JP2023531729A5 - - Google Patents

Info

Publication number
JP2023531729A5
JP2023531729A5 JP2022579985A JP2022579985A JP2023531729A5 JP 2023531729 A5 JP2023531729 A5 JP 2023531729A5 JP 2022579985 A JP2022579985 A JP 2022579985A JP 2022579985 A JP2022579985 A JP 2022579985A JP 2023531729 A5 JP2023531729 A5 JP 2023531729A5
Authority
JP
Japan
Prior art keywords
pharmaceutical composition
composition according
lymphocytes
exon
population
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022579985A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023531729A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/039022 external-priority patent/WO2021263070A1/en
Publication of JP2023531729A publication Critical patent/JP2023531729A/ja
Publication of JP2023531729A5 publication Critical patent/JP2023531729A5/ja
Pending legal-status Critical Current

Links

JP2022579985A 2020-06-26 2021-06-25 キルスイッチを有するドナーt細胞 Pending JP2023531729A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063044697P 2020-06-26 2020-06-26
US63/044,697 2020-06-26
PCT/US2021/039022 WO2021263070A1 (en) 2020-06-26 2021-06-25 Donor t-cells with kill switch

Publications (2)

Publication Number Publication Date
JP2023531729A JP2023531729A (ja) 2023-07-25
JP2023531729A5 true JP2023531729A5 (enExample) 2024-12-13

Family

ID=77022239

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022579985A Pending JP2023531729A (ja) 2020-06-26 2021-06-25 キルスイッチを有するドナーt細胞

Country Status (6)

Country Link
US (1) US20230355674A1 (enExample)
EP (1) EP4172335A1 (enExample)
JP (1) JP2023531729A (enExample)
CN (1) CN115997015A (enExample)
AU (1) AU2021294317A1 (enExample)
WO (1) WO2021263070A1 (enExample)

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5958928A (en) 1995-03-27 1999-09-28 Chugai Seiyaku Kabushiki Kaisha Pharmaceutical agents containing methotrexate derivative
US6013516A (en) 1995-10-06 2000-01-11 The Salk Institute For Biological Studies Vector and method of use for nucleic acid delivery to non-dividing cells
EP1191097A1 (en) 2000-09-21 2002-03-27 Leids Universitair Medisch Centrum Induction of exon skipping in eukaryotic cells
EP2933332A1 (en) 2004-06-28 2015-10-21 The University Of Western Australia Antisense oligonucleotides for inducing exon skipping and methods of use thereof
WO2007098089A2 (en) 2006-02-17 2007-08-30 Novacea, Inc. Treatment of hyperproliferative diseases with methotrexate n-oxide and analogs
CN103849629B (zh) 2006-06-21 2017-06-09 尤尼克尔Ip股份有限公司 具有经修饰的用于在昆虫细胞中产生aav的aav‑rep78翻译起始密码子的载体
BR122020021379B1 (pt) 2008-10-24 2021-05-11 Sarepta Therapeutics, Inc. oligômero morfolino fosforodiamidato, composição que compreende o mesmo e uso do dito oligômero para tratar distrofia muscular
TR201816523T4 (tr) 2009-11-12 2018-11-21 Univ Western Australia Patolojilerin tedavisine yönelik antisens moleküller ve yöntemler.
US9283194B2 (en) 2010-04-16 2016-03-15 The Regents Of The University Of California Methods for protease assisted protein delivery
US9993440B2 (en) 2011-09-02 2018-06-12 The Regents Of The University Of California Enzyme responsive nanocapsules for protein delivery
US20130085139A1 (en) 2011-10-04 2013-04-04 Royal Holloway And Bedford New College Oligomers
CA2907095C (en) 2012-03-16 2020-11-03 The Regents Of The University Of California A novel rnai molecule delivery platform based on single-sirna and shrna nanocapsules
HUE054260T2 (hu) 2012-09-06 2021-08-30 Univ Chicago Antiszensz polinukleotidok exon-ugrás indukálására és eljárások disztrófiák kezelésére
JP6502261B2 (ja) 2012-12-14 2019-04-17 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア ターゲティング遺伝子治療のためのウイルスベクターナノカプセル、およびその調製
US20140329762A1 (en) 2013-03-15 2014-11-06 Sarepta Therapeutics, Inc. Compositions for treating muscular dystrophy
CN105683376A (zh) * 2013-05-15 2016-06-15 桑格摩生物科学股份有限公司 用于治疗遗传病状的方法和组合物
CN107530445B (zh) 2014-11-26 2021-01-05 加利福尼亚大学董事会 用于蛋白质递送的隐形纳米胶囊
HK1247963A1 (zh) 2015-05-18 2018-10-05 Csl贝林基因治疗股份有限公司 用於hiv的治疗的基因疗法及其用途
GB2592821B (en) * 2015-07-31 2022-01-12 Univ Minnesota Modified cells and methods of therapy
EP3463428A4 (en) 2016-05-24 2020-01-08 The Regents of the University of California GROWTH FACTOR NANO CAPSULES WITH TUNABLE RELEASE FOR BONE REGENERATION
WO2018164457A1 (ko) * 2017-03-06 2018-09-13 기초과학연구원 C2cL 엔도뉴클레아제를 포함하는 유전체 교정용 조성물 및 이를 이용한 유전체 교정 방법
JP7410856B2 (ja) * 2017-07-18 2024-01-10 シーエスエル・ベーリング・ジーン・セラピー・インコーポレイテッド ドナー改変細胞の選択のための調節可能スイッチ
US20210228630A1 (en) * 2018-05-16 2021-07-29 Research Institute At Nationwide Children's Hospital Generation of knock-out primary and expanded human nk cells using cas9 ribonucleoproteins
KR20210118833A (ko) * 2018-12-23 2021-10-01 씨에스엘 베링 엘엘씨 킬 스위치를 갖는 공여 t 세포

Similar Documents

Publication Publication Date Title
US20230287401A1 (en) Rna guided compositions for preventing and treating hepatitis b virus infections
JP7176737B2 (ja) レトロウイルス核酸配列の切除
JP5711666B2 (ja) 白血球への効率的輸送
JP2019517503A (ja) 遺伝子編集戦略によるhiv−1のネガティブフィードバック調節
JP2018531261A6 (ja) Cpf1を用いた、rnaガイド遺伝子編集方法および組成物
JP2018531261A (ja) Cpf1を用いた、rnaガイド遺伝子編集方法および組成物
JP2018527943A (ja) Rna誘導性の、hiv感染の処置のための、方法および組成物
CN107075515A (zh) C/EBPα组合物和使用方法
JP2020530463A (ja) ウイルスの細胞内送達のためのペプチドおよびナノ粒子
JP7385847B2 (ja) snoRNAの発現抑制剤を有効成分とするがん増殖抑制剤
JP2021515576A5 (enExample)
JP2004528266A (ja) 薬物送達用組成物
WO2019183246A1 (en) Compositions and methods of fas inhibition
JP2022543446A (ja) Apoe4 rna特異的トランススプライシングリボザイム及びその用途
WO2018194876A1 (en) An hiv-1 eradication strategy employing nanoformulated anti-retroviral drugs and gene editing agents
JP2022514954A5 (enExample)
JP2023531729A5 (enExample)
US20240123034A1 (en) Mrnas encoding granulocyte-macrophage colony stimulating factor for treating parkinson's disease
US20190085326A1 (en) Negative feedback regulation of HIV-1 by gene editing strategy
EP3884055A1 (en) Double and inducible suicide gene construct and its use in gene therapy
CN115161289B (zh) 一种用于炎症性疾病治疗的重组腺相关病毒及其构建方法和应用
US20240318147A1 (en) Recombinant oncolytic virus, and construction method therefor and use thereof
US20230070049A1 (en) Microrna-7 compositions for promoting functional recovery following spinal cord injury and methods of use thereof
Akki et al. A Review Article on Gene Therapy
Nabel Gene therapy approaches to AIDS