JP2023528435A - 遺伝子転写物のモジュレーターを使用する神経学的疾患の処置 - Google Patents

遺伝子転写物のモジュレーターを使用する神経学的疾患の処置 Download PDF

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JP2023528435A
JP2023528435A JP2022574357A JP2022574357A JP2023528435A JP 2023528435 A JP2023528435 A JP 2023528435A JP 2022574357 A JP2022574357 A JP 2022574357A JP 2022574357 A JP2022574357 A JP 2022574357A JP 2023528435 A JP2023528435 A JP 2023528435A
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oligonucleotide
spacer
stmn2
seq
linkage
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JP2023528435A5 (OSRAM
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エルバウム，ダニエル
ヒンクリー，サンドラ
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クラリス コーポレーション
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JP2022574357A 2020-06-03 2021-06-03 遺伝子転写物のモジュレーターを使用する神経学的疾患の処置 Pending JP2023528435A (ja)

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US202063033926P 2020-06-03 2020-06-03
US63/033,926 2020-06-03
US202063119717P 2020-12-01 2020-12-01
US63/119,717 2020-12-01
PCT/US2021/035603 WO2021247800A2 (en) 2020-06-03 2021-06-03 Treatment of neurological diseases using modulators of gene transcripts

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JP2023528435A true JP2023528435A (ja) 2023-07-04
JP2023528435A5 JP2023528435A5 (OSRAM) 2024-06-10

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US (1) US20230235332A1 (OSRAM)
EP (1) EP4162051A4 (OSRAM)
JP (1) JP2023528435A (OSRAM)
KR (1) KR20230043819A (OSRAM)
AU (1) AU2021284360A1 (OSRAM)
CA (1) CA3185488A1 (OSRAM)
IL (1) IL298647A (OSRAM)
WO (1) WO2021247800A2 (OSRAM)

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GB202208387D0 (en) * 2022-06-08 2022-07-20 Ucl Business Ltd Modified U7 snRNA construct
WO2026080323A1 (en) 2024-10-09 2026-04-16 Quralis Corporation Treatment of neurological diseases using modulators of unc13a gene transcripts

Citations (1)

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WO2020247419A2 (en) * 2019-06-03 2020-12-10 Quralis Corporation Oligonucleotides and methods of use for treating neurological diseases

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WO1998013527A2 (en) * 1996-09-24 1998-04-02 Rapigene, Inc. Compositions and methods for enhancing hybridization specificity
WO2006017522A2 (en) * 2004-08-03 2006-02-16 University Of Utah Research Foundation Use of antisense oligonucleotides to effect translation modulation
AU2011325956B2 (en) * 2010-11-12 2016-07-14 The General Hospital Corporation Polycomb-associated non-coding RNAs
US11833168B2 (en) * 2018-06-14 2023-12-05 Ionis Pharmaceuticals, Inc. Compounds and methods for increasing STMN2 expression
CN114173821A (zh) * 2019-01-14 2022-03-11 哈佛学院校长同事会 用于恢复stmn2水平的方法和组合物
EP4127172A4 (en) * 2020-03-25 2025-06-04 President and Fellows of Harvard College Methods and compositions for restoring STMN2 levels

Patent Citations (1)

* Cited by examiner, † Cited by third party
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WO2020247419A2 (en) * 2019-06-03 2020-12-10 Quralis Corporation Oligonucleotides and methods of use for treating neurological diseases

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KR20230043819A (ko) 2023-03-31
CA3185488A1 (en) 2021-12-09
EP4162051A2 (en) 2023-04-12
WO2021247800A3 (en) 2022-01-06
AU2021284360A1 (en) 2023-01-19
IL298647A (en) 2023-01-01
US20230235332A1 (en) 2023-07-27
WO2021247800A2 (en) 2021-12-09
EP4162051A4 (en) 2025-07-09

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