JP2023527525A5 - - Google Patents

Info

Publication number
JP2023527525A5
JP2023527525A5 JP2022571117A JP2022571117A JP2023527525A5 JP 2023527525 A5 JP2023527525 A5 JP 2023527525A5 JP 2022571117 A JP2022571117 A JP 2022571117A JP 2022571117 A JP2022571117 A JP 2022571117A JP 2023527525 A5 JP2023527525 A5 JP 2023527525A5
Authority
JP
Japan
Prior art keywords
virus
tissue
immunostimulatory oligonucleotide
composition
duplex
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022571117A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023527525A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/033617 external-priority patent/WO2021237067A1/en
Publication of JP2023527525A publication Critical patent/JP2023527525A/ja
Publication of JP2023527525A5 publication Critical patent/JP2023527525A5/ja
Pending legal-status Critical Current

Links

JP2022571117A 2020-05-22 2021-05-21 インターフェロン誘導オリゴヌクレオチド二重鎖および使用方法 Pending JP2023527525A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202063029199P 2020-05-22 2020-05-22
US63/029,199 2020-05-22
US202063082742P 2020-09-24 2020-09-24
US63/082,742 2020-09-24
PCT/US2021/033617 WO2021237067A1 (en) 2020-05-22 2021-05-21 Interferon- inducing oligonucleotide duplexes and methods of use

Publications (2)

Publication Number Publication Date
JP2023527525A JP2023527525A (ja) 2023-06-29
JP2023527525A5 true JP2023527525A5 (https=) 2024-04-16

Family

ID=78707688

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022571117A Pending JP2023527525A (ja) 2020-05-22 2021-05-21 インターフェロン誘導オリゴヌクレオチド二重鎖および使用方法

Country Status (4)

Country Link
US (1) US20230242918A1 (https=)
EP (1) EP4153752A4 (https=)
JP (1) JP2023527525A (https=)
WO (1) WO2021237067A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022159383A1 (en) * 2021-01-19 2022-07-28 President And Fellows Of Harvard College Engineered nucleic acids targeting long noncoding rna involved in pathogenic infection
CN118948865B (zh) * 2024-10-15 2025-03-25 佛山大学 维奈妥拉abt-199在制备防治轮状病毒的药物中的应用

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020028784A1 (en) * 2000-03-10 2002-03-07 Nest Gary Van Methods of preventing and treating viral infections using immunomodulatory polynucleotide sequences
EP1456380B1 (en) * 2001-11-02 2012-04-18 Giuliani International Limited Smad7 inhibitors for the treatment of cns diseases
CN1590545A (zh) * 2003-06-04 2005-03-09 杭州新瑞佳生物医药技术开发有限公司 攻击SARS病毒mRNA分子的小干扰核糖核酸分子（SiRNA）及应用
US7842459B2 (en) * 2004-01-27 2010-11-30 Compugen Ltd. Nucleotide and amino acid sequences, and assays and methods of use thereof for diagnosis
WO2005116204A1 (ja) * 2004-05-11 2005-12-08 Rnai Co., Ltd. Ｒｎａ干渉を生じさせるポリヌクレオチド、および、これを用いた遺伝子発現抑制方法
EP1773857A4 (en) * 2004-07-02 2009-05-13 Protiva Biotherapeutics Inc THE IMMUNE SYSTEM STIMULATING SIRNA MOLECULES AND APPLICATIONS THEREOF
US20060178334A1 (en) * 2005-02-04 2006-08-10 City Of Hope Double-stranded and single-stranded RNA molecules with 5 ' triphosphates and their use for inducing interferon
EP1764108A1 (en) * 2005-09-14 2007-03-21 Gunther Hartmann Compositions comprising immunostimulatory RNA oligonucleotides and methods for producing said RNA oligonucleotides
DK2405002T3 (en) * 2006-02-15 2015-01-05 Adiutide Pharmaceuticals Gmbh Compositions and methods for oligonukleotidformuleringer
ES2911034T3 (es) * 2006-08-08 2022-05-17 Univ Bonn Rheinische Friedrich Wilhelms Estructura y uso de oligonucleótidos 5' fosfato
US9023820B2 (en) * 2009-01-26 2015-05-05 Protiva Biotherapeutics, Inc. Compositions and methods for silencing apolipoprotein C-III expression
US9040234B2 (en) * 2010-08-30 2015-05-26 Spring Bank Pharmaceuticals, Inc. Oligonucleotide analogs as therapeutic agents
WO2012079115A1 (en) * 2010-12-14 2012-06-21 Commonwealth Scientific And Industrial Research Organisation Immunostimulatory oligonucleotides
WO2012145582A2 (en) * 2011-04-22 2012-10-26 Dicerna Pharmaceuticals, Inc. Methods and compositions for the specific inhibitions of egfr by double-stranded rna
US9670488B2 (en) * 2011-11-04 2017-06-06 Dicerna Pharmaceuticals, Inc. Methods and compositions for the specific inhibition of met by double stranded RNA
EP2712870A1 (en) * 2012-09-27 2014-04-02 Rheinische Friedrich-Wilhelms-Universität Bonn Novel RIG-I ligands and methods for producing them
EP3581654B1 (en) * 2013-12-27 2021-03-31 Dicerna Pharmaceuticals, Inc. Methods and compositions for the specific inhibition of glycolate oxidase (hao1) by double-stranded rna
CN104630223B (zh) * 2014-12-22 2017-10-31 淮阴工学院 包含POKEMON基因的siRNA的运输载体颗粒及其制备方法
JP7735288B2 (ja) * 2020-02-18 2025-09-08 アルナイラム ファーマシューティカルズ， インコーポレイテッド アポリポタンパク質Ｃ３（ＡＰＯＣ３）ｉＲＮＡ組成物およびその使用法
CN111748557B (zh) * 2020-04-03 2022-03-11 苏州吉玛基因股份有限公司 抑制新型冠状病毒的小干扰核酸及组合物和应用

Similar Documents

Publication Publication Date Title
De Clercq Antivirals: past, present and future
Razonable Antiviral drugs for viruses other than human immunodeficiency virus
TWI796665B (zh) 1'-氰基經取代碳核苷類似物之吸入式調配物
de Clercq Milestones in the discovery of antiviral agents: nucleosides and nucleotides
HRP20201075T1 (hr) 4,6-diamino-pirido[3,2-d]pirimidinski spojevi i njihova upotreba kao modulatora receptora sličnih tolu
JP2017203033A5 (https=)
JP2023539542A5 (https=)
JP2023527525A5 (https=)
US20230322813A1 (en) Compounds and methods for treatment of viral infections
CN108135979A (zh) Hbv衣壳组装抑制剂和干扰素的组合疗法
JP2018531272A6 (ja) Ｈｂｖキャプシドアセンブリ阻害剤とインターフェロンの併用療法
RU2411039C2 (ru) Иммунокорригирующее средство для лечения заболеваний вирусной этиологии
US20210353650A1 (en) Pharmaceutical formulation containing remdesivir and its active metabolites for dry powder inhalation
JP2010270130A5 (https=)
CN111467338A (zh) 焦谷氨酸在制备预防和治疗抗新冠肺炎新型冠状病毒的药物中的应用
JP2024545086A (ja) 抗ウイルス治療剤及びその使用
AU2024353008A1 (en) Compounds and methods for treatment of viral infections
CN113069446B (zh) El102在制备治疗新型冠状病毒所致疾病的药物中的应用
TW202017939A (zh) 貽貝黏著蛋白的抗病毒用途
US20110318298A1 (en) Viral infection therapeutic drug containing polyalkyleneimine
TW202126304A (zh) 使用核心蛋白異位調節劑治療hbv感染之方法
WO2020055368A2 (en) Usage of terpenic coumarin derived molecules in treating viral diseases
JP2017535549A5 (https=)
IL252190B2 (en) Anti- human cytomegalovirus compounds and compositions
US11654121B1 (en) Combination therapies for the treatment of viral infections