JP2023526428A5 - - Google Patents

Info

Publication number
JP2023526428A5
JP2023526428A5 JP2022570534A JP2022570534A JP2023526428A5 JP 2023526428 A5 JP2023526428 A5 JP 2023526428A5 JP 2022570534 A JP2022570534 A JP 2022570534A JP 2022570534 A JP2022570534 A JP 2022570534A JP 2023526428 A5 JP2023526428 A5 JP 2023526428A5
Authority
JP
Japan
Prior art keywords
polypeptide
protease
antigen
subunit
life extension
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022570534A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023526428A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/033014 external-priority patent/WO2021236676A1/en
Publication of JP2023526428A publication Critical patent/JP2023526428A/ja
Publication of JP2023526428A5 publication Critical patent/JP2023526428A5/ja
Priority to JP2025227145A priority Critical patent/JP2026031678A/ja
Pending legal-status Critical Current

Links

JP2022570534A 2020-05-19 2021-05-18 活性化可能なil-12ポリペプチド及びその使用方法 Pending JP2023526428A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025227145A JP2026031678A (ja) 2020-05-19 2025-12-03 活性化可能なil-12ポリペプチド及びその使用方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063027276P 2020-05-19 2020-05-19
US63/027,276 2020-05-19
PCT/US2021/033014 WO2021236676A1 (en) 2020-05-19 2021-05-18 Activatable il-12 polypeptides and methods of use thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025227145A Division JP2026031678A (ja) 2020-05-19 2025-12-03 活性化可能なil-12ポリペプチド及びその使用方法

Publications (2)

Publication Number Publication Date
JP2023526428A JP2023526428A (ja) 2023-06-21
JP2023526428A5 true JP2023526428A5 (enExample) 2024-05-24

Family

ID=76375661

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2022570534A Pending JP2023526428A (ja) 2020-05-19 2021-05-18 活性化可能なil-12ポリペプチド及びその使用方法
JP2025227145A Pending JP2026031678A (ja) 2020-05-19 2025-12-03 活性化可能なil-12ポリペプチド及びその使用方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025227145A Pending JP2026031678A (ja) 2020-05-19 2025-12-03 活性化可能なil-12ポリペプチド及びその使用方法

Country Status (11)

Country Link
US (1) US20240043488A1 (enExample)
EP (1) EP4153612A1 (enExample)
JP (2) JP2023526428A (enExample)
KR (1) KR20230012564A (enExample)
CN (1) CN116096738A (enExample)
AU (1) AU2021276337A1 (enExample)
BR (1) BR112022023288A2 (enExample)
CA (1) CA3178657A1 (enExample)
IL (1) IL298295A (enExample)
MX (1) MX2022014411A (enExample)
WO (1) WO2021236676A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI880235B (zh) 2017-11-28 2025-04-11 日商中外製藥股份有限公司 可調整配體結合活性的配體結合分子
WO2021016599A1 (en) * 2019-07-25 2021-01-28 Trutino Biosciences Inc Il-2 cytokine prodrugs comprising a cleavable linker
WO2021207669A1 (en) 2020-04-10 2021-10-14 Cytomx Therapeutics, Inc. Activatable cytokine constructs and related compositions and methods
IL298136A (en) 2020-05-13 2023-01-01 Bonum Therapeutics Inc Preparations of protein complexes and methods of using them
BR112023018735A2 (pt) 2021-03-16 2023-11-28 Cytomx Therapeutics Inc Construtos de citocinas ativáveis mascarados e composições e métodos relacionados
US20250114489A1 (en) 2022-02-15 2025-04-10 Tagworks Pharmaceuticals B.V. Masked il12 protein
WO2023196897A1 (en) * 2022-04-07 2023-10-12 Werewolf Therapeutics Inc. Il-12 prodrugs
WO2024124164A2 (en) * 2022-12-09 2024-06-13 The Trustees Of The University Of Pennsylvania Compositions and methods for delivery of immunostimulatory cytokines to chimeric antigen receptor immune cells
AR131624A1 (es) * 2023-01-18 2025-04-16 Chugai Pharmaceutical Co Ltd Citoquina activada por proteasa
WO2024211877A2 (en) * 2023-04-06 2024-10-10 Werewolf Therapeutics, Inc. Il-12 prodrugs, methods of use and pharmaceutical compositions
WO2025072450A1 (en) 2023-09-26 2025-04-03 Werewolf Therapeutics, Inc. Enhanced adoptive cell therapy
WO2026072455A1 (en) 2024-09-26 2026-04-02 Werewolf Therapeutics, Inc. Single domain human serum albumin antibodies

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006110728A2 (en) 2005-04-12 2006-10-19 The Uab Research Foundation Immunogenic cmv tegument aggregates
US10696722B2 (en) * 2016-08-10 2020-06-30 Ajou University Industry-Academic Cooperation Foundation Heterodimeric Fc-fused cytokine and pharmaceutical composition comprising the same
US10472816B2 (en) 2017-07-26 2019-11-12 Justin Griebel Backflow valve assembly
WO2019222296A1 (en) * 2018-05-14 2019-11-21 Werewolf Therapeutics, Inc. Activatable interleukin 12 polypeptides and methods of use thereof
US20220002370A1 (en) * 2018-09-27 2022-01-06 Xilio Development, Inc. Masked cytokine polypeptides
AU2020353235A1 (en) * 2019-09-28 2022-03-31 AskGene Pharma, Inc. Cytokine prodrugs and dual-prodrugs
JP7773991B2 (ja) * 2020-03-23 2025-11-20 ザイムワークス ビーシー インコーポレイテッド マスクされたil12融合タンパク質及びその使用方法

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