JP2025511713A5 - - Google Patents
Info
- Publication number
- JP2025511713A5 JP2025511713A5 JP2024559144A JP2024559144A JP2025511713A5 JP 2025511713 A5 JP2025511713 A5 JP 2025511713A5 JP 2024559144 A JP2024559144 A JP 2024559144A JP 2024559144 A JP2024559144 A JP 2024559144A JP 2025511713 A5 JP2025511713 A5 JP 2025511713A5
- Authority
- JP
- Japan
- Prior art keywords
- heavy chain
- sequence
- sequence numbers
- antibody
- nos
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNPCT/CN2022/085838 | 2022-04-08 | ||
| PCT/CN2022/085838 WO2023193239A1 (en) | 2022-04-08 | 2022-04-08 | Anti-cd28 antibodies and methods of use thereof |
| PCT/CN2023/087277 WO2023193817A1 (en) | 2022-04-08 | 2023-04-10 | Anti-cd28 antibodies and methods of use thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025511713A JP2025511713A (ja) | 2025-04-16 |
| JP2025511713A5 true JP2025511713A5 (enExample) | 2026-04-17 |
Family
ID=86332084
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024559144A Pending JP2025511713A (ja) | 2022-04-08 | 2023-04-10 | 抗cd28抗体及びその使用方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20250257133A1 (enExample) |
| EP (1) | EP4504787A1 (enExample) |
| JP (1) | JP2025511713A (enExample) |
| KR (1) | KR20250008811A (enExample) |
| CN (1) | CN120112552A (enExample) |
| AU (1) | AU2023250992A1 (enExample) |
| CA (1) | CA3255415A1 (enExample) |
| IL (1) | IL316065A (enExample) |
| MX (1) | MX2024012474A (enExample) |
| TW (1) | TW202409082A (enExample) |
| WO (2) | WO2023193239A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115279796A (zh) * | 2020-01-23 | 2022-11-01 | 天演药业(瑞士)公司 | 具有Fc突变的异二聚蛋白质 |
| US12195546B2 (en) | 2022-12-19 | 2025-01-14 | Sanofi | CD28/OX40 bispecific antibodies |
| CN120904324A (zh) * | 2024-04-30 | 2025-11-07 | 惠和生物技术(上海)有限公司 | 抗cd28抗体及其用途 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5179017A (en) | 1980-02-25 | 1993-01-12 | The Trustees Of Columbia University In The City Of New York | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
| US4399216A (en) | 1980-02-25 | 1983-08-16 | The Trustees Of Columbia University | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
| US4634665A (en) | 1980-02-25 | 1987-01-06 | The Trustees Of Columbia University In The City Of New York | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| GB8601597D0 (en) | 1986-01-23 | 1986-02-26 | Wilson R H | Nucleotide sequences |
| GB8717430D0 (en) | 1987-07-23 | 1987-08-26 | Celltech Ltd | Recombinant dna product |
| GB8809129D0 (en) | 1988-04-18 | 1988-05-18 | Celltech Ltd | Recombinant dna methods vectors and host cells |
| US5731168A (en) | 1995-03-01 | 1998-03-24 | Genentech, Inc. | Method for making heteromultimeric polypeptides |
| US5948893A (en) * | 1996-01-17 | 1999-09-07 | The United States Of America As Represented By The Secretary Of The Navy | Murine hybridoma and antibody binding to CD28 receptor secreted by the hybridoma and method of using the antibody |
| US5994619A (en) | 1996-04-01 | 1999-11-30 | University Of Massachusetts, A Public Institution Of Higher Education Of The Commonwealth Of Massachusetts, As Represented By Its Amherst Campus | Production of chimeric bovine or porcine animals using cultured inner cell mass cells |
| AR039067A1 (es) | 2001-11-09 | 2005-02-09 | Pfizer Prod Inc | Anticuerpos para cd40 |
| US7771951B2 (en) | 2001-12-03 | 2010-08-10 | Amgen Fremont Inc. | Antibody categorization based on binding characteristics |
| PT2171060E (pt) * | 2004-11-11 | 2013-11-18 | Theramab Llc | Anticorpo anti-cd28 superagonista |
| US7585960B2 (en) * | 2005-05-11 | 2009-09-08 | Theramab Gmbh | Nucleic acids encoding superagonistic anti-CD28 antibodies |
| AU2015202447B2 (en) * | 2008-07-18 | 2017-01-19 | Bristol-Myers Squibb Company | Compositions monovalent for cd28 binding and methods of use |
| US9382329B2 (en) * | 2012-08-14 | 2016-07-05 | Ibc Pharmaceuticals, Inc. | Disease therapy by inducing immune response to Trop-2 expressing cells |
| WO2014120916A1 (en) * | 2013-02-01 | 2014-08-07 | Bristol-Myers Squibb Company | Pegylated domain antibodies monovalent for cd28 binding and methods of use |
| IL272696B2 (en) * | 2017-08-21 | 2025-01-01 | Adagene Inc | Dynamic human heavy chain antibody libraries |
| WO2019148445A1 (en) * | 2018-02-02 | 2019-08-08 | Adagene Inc. | Precision/context-dependent activatable antibodies, and methods of making and using the same |
| CA3095076A1 (en) | 2018-03-29 | 2019-10-03 | Adagene Inc. | Anti-pd-l1 antibodies and use thereof |
| IL279354B1 (en) | 2018-06-21 | 2026-02-01 | Regeneron Pharma | Bispecific antibodies against psma and against cd28 and their uses |
| CN115279796A (zh) | 2020-01-23 | 2022-11-01 | 天演药业(瑞士)公司 | 具有Fc突变的异二聚蛋白质 |
| JP7789002B2 (ja) * | 2020-01-29 | 2025-12-19 | インヒブルクス バイオサイエンシズ インコーポレイテッド | Cd28シングルドメイン抗体ならびにその多価および多重特異性の構築物 |
| AU2021295549A1 (en) * | 2020-06-23 | 2022-11-24 | F. Hoffmann-La Roche Ag | Agonistic CD28 antigen binding molecules targeting Her2 |
| CA3192204A1 (en) * | 2020-08-19 | 2022-02-24 | Xencor, Inc. | Anti-cd28 and/or anti-b7h3 compositions |
-
2022
- 2022-04-08 WO PCT/CN2022/085838 patent/WO2023193239A1/en not_active Ceased
-
2023
- 2023-04-10 JP JP2024559144A patent/JP2025511713A/ja active Pending
- 2023-04-10 US US18/855,066 patent/US20250257133A1/en active Pending
- 2023-04-10 WO PCT/CN2023/087277 patent/WO2023193817A1/en not_active Ceased
- 2023-04-10 EP EP23723108.9A patent/EP4504787A1/en active Pending
- 2023-04-10 AU AU2023250992A patent/AU2023250992A1/en active Pending
- 2023-04-10 CN CN202380044740.2A patent/CN120112552A/zh active Pending
- 2023-04-10 IL IL316065A patent/IL316065A/en unknown
- 2023-04-10 CA CA3255415A patent/CA3255415A1/en active Pending
- 2023-04-10 KR KR1020247037360A patent/KR20250008811A/ko active Pending
- 2023-04-10 TW TW112113303A patent/TW202409082A/zh unknown
-
2024
- 2024-10-08 MX MX2024012474A patent/MX2024012474A/es unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP7596450B2 (ja) | 活性化可能抗体ならびにその作製及び使用方法 | |
| JP2025511713A5 (enExample) | ||
| EP2609112B1 (en) | Activatable bispecific antibodies | |
| JP2021511808A5 (enExample) | ||
| CN116419925A (zh) | 受限的条件激活的结合蛋白 | |
| US12428494B2 (en) | Compositions targeting prostate-specific membrane antigen and methods for making and using the same | |
| JP2025160226A (ja) | Fc変異を有するヘテロダイマータンパク質 | |
| IL298815A (en) | Bispecific compositions targeting HER-2 and methods for their preparation and use | |
| US12590159B2 (en) | Compositions targeting epidermal growth factor receptor and methods for making and using the same | |
| JP2025509272A5 (enExample) | ||
| JP2024542978A5 (enExample) | ||
| US20250333539A1 (en) | Activatable antigen-binding protein constructs and uses of the same | |
| JP7855148B2 (ja) | 前立腺特異的膜抗原(psma)を標的とする組成物、並びにそれを作製及び使用するための方法 | |
| WO2024213109A1 (en) | Masked antibodies, libraries and methods of use | |
| US20250326847A1 (en) | Activatable anti-ctla4 antibodies for treating cancer | |
| NZ767462B2 (en) | Anti-ctla4 antibodies and methods of making and using the same | |
| NZ767462A (en) | Anti-ctla4 antibodies and methods of making and using the same | |
| Gerspach | Activatable bispecific antibodies The current invention relates to bispecific antibodies wherein the binding affinity to one of the two antigens is reduced and which can be activated by tumor-or inflammation-tissue/disease specific proteases (eg tumor-or inflammation-specific proteases); and the preparation and use of such bispecific antibodies. |