JP2023524912A5 - - Google Patents
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- Publication number
- JP2023524912A5 JP2023524912A5 JP2023509462A JP2023509462A JP2023524912A5 JP 2023524912 A5 JP2023524912 A5 JP 2023524912A5 JP 2023509462 A JP2023509462 A JP 2023509462A JP 2023509462 A JP2023509462 A JP 2023509462A JP 2023524912 A5 JP2023524912 A5 JP 2023524912A5
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063014346P | 2020-04-23 | 2020-04-23 | |
| US63/014,346 | 2020-04-23 | ||
| PCT/US2021/028726 WO2021216936A1 (en) | 2020-04-23 | 2021-04-22 | Composition for treating blood cancer using 4'-thio-5-aza-2'-deoxycytidine and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023524912A JP2023524912A (ja) | 2023-06-13 |
| JPWO2021216936A5 JPWO2021216936A5 (https=) | 2024-05-01 |
| JP2023524912A5 true JP2023524912A5 (https=) | 2024-05-01 |
Family
ID=78221459
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023509462A Pending JP2023524912A (ja) | 2020-04-23 | 2021-04-22 | ４’－チオ－５－アザ－２’－デオキシシチジンを使用して血液がんを治療するための組成物及びその使用 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US12208112B2 (https=) |
| EP (1) | EP4138843A4 (https=) |
| JP (1) | JP2023524912A (https=) |
| KR (1) | KR20230004768A (https=) |
| CN (1) | CN115768432A (https=) |
| AU (1) | AU2021260964A1 (https=) |
| CA (1) | CA3176543A1 (https=) |
| WO (1) | WO2021216936A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3097003A1 (en) * | 2018-04-19 | 2019-10-24 | Southern Research Institute | 4'-thio-nucleotide and -nucleoside prodrugs for the treatment of cancer |
| KR20240108406A (ko) | 2021-10-19 | 2024-07-09 | 아키라바이오, 인크. | 2'-데옥시시티딘 유사체를 포함하는 조성물 및 겸상 적혈구 질환, 지중해빈혈, 및 암의 치료를 위한 그의 용도 |
| WO2024191252A1 (ko) * | 2023-03-14 | 2024-09-19 | 주식회사 피노바이오 | 골수에 작용하는 5-아자-4'-티오-2'-데옥시사이티딘의 최고 혈중농도를 정교하게 제어가능한 경구용 제형 |
| CN117187391B (zh) * | 2023-09-15 | 2025-03-18 | 中国医学科学院北京协和医院 | 普卡霉素在垂体促肾上腺皮质激素腺瘤中的应用 |
| WO2025100762A1 (ko) * | 2023-11-08 | 2025-05-15 | 한국생명공학연구원 | 4'-티오-5-아자-2'-디옥시사이티딘을 포함하는 간질환의 개선, 예방 또는 치료용 조성물 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6020322A (en) | 1993-11-09 | 2000-02-01 | Pro-Neuron, Inc. | Acyl deoxyribonucleoside derivatives and uses thereof |
| US5591722A (en) | 1989-09-15 | 1997-01-07 | Southern Research Institute | 2'-deoxy-4'-thioribonucleosides and their antiviral activity |
| ES2402799T3 (es) | 1998-07-23 | 2013-05-09 | Southern Research Institute | Prepreparación de compuestos de tioarabinofuranosilo y utilización de los mismos |
| WO2004018494A1 (ja) | 2002-08-22 | 2004-03-04 | Geneticlab Co., Ltd. | ４’−チオヌクレオチド |
| US20060014949A1 (en) | 2004-07-13 | 2006-01-19 | Supergen Inc. | Compositions and formulations of decitabine polymorphs and methods of use thereof |
| KR101125932B1 (ko) | 2006-12-06 | 2012-03-22 | 아이디유엔 파마슈티칼즈, 인코포레이티드 | (3ｓ)-3-［ｎ-(ｎ'-(2-ｔｅｒｔ-부틸페닐)옥사밀)알라니닐］아미노-5-(2',3',5',6'-테트라플루오로페녹시)-4-옥소펜탄산의 결정 형태 |
| EP3782612B1 (en) | 2008-05-15 | 2023-11-08 | Celgene Corporation | Oral formulations of cytidine analogs and methods of use thereof |
| WO2011109383A1 (en) | 2010-03-02 | 2011-09-09 | Southern Research Institute | Use of 2'-deoxy -4'-thiocytidine and its analogues as dna hypomethylating anticancer agents |
| US20110218170A1 (en) * | 2010-03-02 | 2011-09-08 | Southern Research Institute | Use of 2'-deoxy-4'-thiocytidine and its analogues as dna hypomethylating anticancer agents |
| WO2011109012A1 (en) * | 2010-03-02 | 2011-09-09 | Southern Research Institute | Use of 2'-deoxy-4'-thiocytidine and its analogues as dna hypomethylating anticancer agents |
| BR112016028641A2 (pt) * | 2014-07-14 | 2017-08-22 | Gilead Sciences Inc | ?método para tratar câncer? |
| TWI678373B (zh) | 2014-10-31 | 2019-12-01 | 日商富士軟片股份有限公司 | 硫代核苷衍生物或其鹽及醫藥組合物 |
| US10662214B2 (en) | 2015-04-03 | 2020-05-26 | Sichuan Keiun-Biotech Biopharmaceutical Co., Ltd. | Compound of 4′-thionucleoside, as well as preparation method therefor, pharmaceutical composition thereof and application thereof |
| US20160312261A1 (en) | 2015-04-24 | 2016-10-27 | Plasmia Biotech, S.L. | Enzymatic production of cytosinic nucleoside analogues |
| HK1252245A1 (zh) | 2015-05-27 | 2019-05-24 | Idenix Pharmaceuticals Llc | 用於治疗癌症的核苷酸 |
| EP3207932A1 (en) * | 2016-02-19 | 2017-08-23 | Universität Stuttgart | Dna methyltransferase inhibitors for rett syndrome therapy |
| US20190240210A1 (en) * | 2016-10-17 | 2019-08-08 | Daiichi Sankyo Company, Limited | Treatment Method by Combined Use of MDM2 Inhibitor and DNA Methyltransferase Inhibitor |
| JP7425734B2 (ja) | 2018-02-01 | 2024-01-31 | ザ ユナイテッド ステイツ オブ アメリカ， アズ リプレゼンテッド バイ ザ セクレタリー， デパートメント オブ ヘルス アンド ヒューマン サービシーズ | ２’－デオキシヌクレオシドを製造するための立体選択的合成およびプロセス |
| CA3097003A1 (en) * | 2018-04-19 | 2019-10-24 | Southern Research Institute | 4'-thio-nucleotide and -nucleoside prodrugs for the treatment of cancer |
| JP7520822B2 (ja) | 2018-09-25 | 2024-07-23 | ザ ユナイテッド ステイツ オブ アメリカ， アズ リプレゼンテッド バイ ザ セクレタリー， デパートメント オブ ヘルス アンド ヒューマン サービシーズ | ２’－ハロゲン化－４’－チオ－２’－デオキシ－５－アザシチジンアナログおよびその使用 |
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2021
- 2021-04-22 EP EP21793672.3A patent/EP4138843A4/en active Pending
- 2021-04-22 AU AU2021260964A patent/AU2021260964A1/en active Pending
- 2021-04-22 US US17/238,182 patent/US12208112B2/en active Active
- 2021-04-22 JP JP2023509462A patent/JP2023524912A/ja active Pending
- 2021-04-22 KR KR1020227040932A patent/KR20230004768A/ko active Pending
- 2021-04-22 CN CN202180039610.0A patent/CN115768432A/zh active Pending
- 2021-04-22 WO PCT/US2021/028726 patent/WO2021216936A1/en not_active Ceased
- 2021-04-22 CA CA3176543A patent/CA3176543A1/en active Pending
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2024
- 2024-11-22 US US18/957,005 patent/US20250082662A1/en active Pending