JP2023524668A - 若年性特発性関節炎を治療するための材料及び方法 - Google Patents

若年性特発性関節炎を治療するための材料及び方法 Download PDF

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JP2023524668A
JP2023524668A JP2022565551A JP2022565551A JP2023524668A JP 2023524668 A JP2023524668 A JP 2023524668A JP 2022565551 A JP2022565551 A JP 2022565551A JP 2022565551 A JP2022565551 A JP 2022565551A JP 2023524668 A JP2023524668 A JP 2023524668A
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tnf
antibody
jia
amino acid
pediatric patient
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JP2023524668A5 (cg-RX-API-DMAC10.html
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ベンズリー，カレン
クラーク，マイケル
ル，ジョスリン
シュー，ジェンファ
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ヤンセン バイオテツク，インコーポレーテツド
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Publication of JP2023524668A5 publication Critical patent/JP2023524668A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241—Tumor Necrosis Factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Farming Of Fish And Shellfish (AREA)
JP2022565551A 2020-04-27 2021-04-26 若年性特発性関節炎を治療するための材料及び方法 Pending JP2023524668A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US202063015894P 2020-04-27 2020-04-27
US202063015902P 2020-04-27 2020-04-27
US202063015889P 2020-04-27 2020-04-27
US63/015,894 2020-04-27
US63/015,889 2020-04-27
US63/015,902 2020-04-27
PCT/IB2021/053429 WO2021220140A1 (en) 2020-04-27 2021-04-26 Materials and methods for treating juvenile idiopathic arthritis

Publications (2)

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JP2023524668A true JP2023524668A (ja) 2023-06-13
JP2023524668A5 JP2023524668A5 (cg-RX-API-DMAC10.html) 2024-05-01

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JP2022565551A Pending JP2023524668A (ja) 2020-04-27 2021-04-26 若年性特発性関節炎を治療するための材料及び方法

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US (1) US20210340245A1 (cg-RX-API-DMAC10.html)
EP (1) EP4143226A4 (cg-RX-API-DMAC10.html)
JP (1) JP2023524668A (cg-RX-API-DMAC10.html)
KR (1) KR20230005284A (cg-RX-API-DMAC10.html)
CN (1) CN115461365A (cg-RX-API-DMAC10.html)
AU (1) AU2021263136A1 (cg-RX-API-DMAC10.html)
BR (1) BR112022021766A2 (cg-RX-API-DMAC10.html)
CA (1) CA3127807A1 (cg-RX-API-DMAC10.html)
IL (1) IL297623A (cg-RX-API-DMAC10.html)
MX (1) MX2022013502A (cg-RX-API-DMAC10.html)
WO (1) WO2021220140A1 (cg-RX-API-DMAC10.html)

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Publication number Priority date Publication date Assignee Title
WO2025034540A1 (en) * 2023-08-10 2025-02-13 Alexion Pharmaceuticals, Inc. Immunosuppressive therapy to mitigate anti-soluble alkaline phosphatase immune response

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019509988A (ja) * 2016-02-05 2019-04-11 ヤンセン バイオテツク，インコーポレーテツド １型糖尿病の処置又は予防のための抗ｔｎｆ抗体、組成物、方法及び使用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5757495B2 (ja) * 2005-05-16 2015-07-29 アッヴィ バイオテクノロジー リミテッド びらん性多発性関節炎の治療のためのｔｎｆ阻害剤の使用
CN110234351A (zh) * 2017-01-30 2019-09-13 詹森生物科技公司 用于治疗活动性银屑病关节炎的抗tnf抗体、组合物和方法

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019509988A (ja) * 2016-02-05 2019-04-11 ヤンセン バイオテツク，インコーポレーテツド １型糖尿病の処置又は予防のための抗ｔｎｆ抗体、組成物、方法及び使用

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
A STUDY TO EVALUATE THE PHARMACOKINETICS, EFFICACY AND SAFETY OF INTRAVENOUS GOLIMUMAB IN PEDIATRIC, vol. NCT02277444, JPN6025017030, ISSN: 0005748813 *
ANNALS OF THE RHEUMATIC DISEASES, vol. 77, no. 1, JPN6025017028, 2018, pages 21 - 29, ISSN: 0005583728 *
ANNALS OF THE RHEUMATIC DISEASES, vol. 78, JPN6025017029, 2019, pages 966, ISSN: 0005748814 *
ARTHRITIS RESEARCH & THERAPY, vol. Vol. 18, article number 272, JPN6025017026, 2016, pages 1 - 12, ISSN: 0005583730 *
CURRENT OPINION IN RHEUMATOLOGY, vol. 27, no. 5, JPN6025017027, 2015, pages 505 - 510, ISSN: 0005583729 *

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Publication number Publication date
IL297623A (en) 2022-12-01
BR112022021766A2 (pt) 2022-12-13
US20210340245A1 (en) 2021-11-04
AU2021263136A1 (en) 2023-01-05
MX2022013502A (es) 2023-02-01
EP4143226A4 (en) 2024-05-29
KR20230005284A (ko) 2023-01-09
CN115461365A (zh) 2022-12-09
WO2021220140A1 (en) 2021-11-04
EP4143226A1 (en) 2023-03-08
CA3127807A1 (en) 2021-10-27

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