JP2023520935A - パルス衝撃波を利用した無針注射器 - Google Patents
パルス衝撃波を利用した無針注射器 Download PDFInfo
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- JP2023520935A JP2023520935A JP2022561502A JP2022561502A JP2023520935A JP 2023520935 A JP2023520935 A JP 2023520935A JP 2022561502 A JP2022561502 A JP 2022561502A JP 2022561502 A JP2022561502 A JP 2022561502A JP 2023520935 A JP2023520935 A JP 2023520935A
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- 230000035939 shock Effects 0.000 title claims abstract description 192
- 239000003814 drug Substances 0.000 claims abstract description 61
- 239000007788 liquid Substances 0.000 claims abstract description 56
- 229940079593 drug Drugs 0.000 claims abstract description 54
- 238000002347 injection Methods 0.000 claims description 29
- 239000007924 injection Substances 0.000 claims description 29
- 230000005540 biological transmission Effects 0.000 claims description 12
- 230000005611 electricity Effects 0.000 claims description 9
- 238000012377 drug delivery Methods 0.000 description 8
- 238000000034 method Methods 0.000 description 7
- 230000003287 optical effect Effects 0.000 description 6
- 230000004308 accommodation Effects 0.000 description 3
- 239000003990 capacitor Substances 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- 230000015556 catabolic process Effects 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 238000003825 pressing Methods 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 206010073753 Fear of injection Diseases 0.000 description 1
- 244000043261 Hevea brasiliensis Species 0.000 description 1
- 206010022086 Injection site pain Diseases 0.000 description 1
- 239000002202 Polyethylene glycol Substances 0.000 description 1
- 206010052428 Wound Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000004020 conductor Substances 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000001647 drug administration Methods 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000002906 medical waste Substances 0.000 description 1
- 229920003052 natural elastomer Polymers 0.000 description 1
- 229920001194 natural rubber Polymers 0.000 description 1
- 230000003071 parasitic effect Effects 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 229920003051 synthetic elastomer Polymers 0.000 description 1
- 239000005061 synthetic rubber Substances 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
Images
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/30—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
- A61M5/3007—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules with specially designed jet passages at the injector's distal end
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/30—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
- A61M5/281—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle using emptying means to expel or eject media, e.g. pistons, deformation of the ampoule, or telescoping of the ampoule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/30—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
- A61M5/3015—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules for injecting a dose of particles in form of powdered drug, e.g. mounted on a rupturable membrane and accelerated by a gaseous shock wave or supersonic gas flow
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/82—Internal energy supply devices
- A61M2205/8206—Internal energy supply devices battery-operated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
- A61M39/22—Valves or arrangement of valves
- A61M39/24—Check- or non-return valves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/34—Constructions for connecting the needle, e.g. to syringe nozzle or needle hub
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Vascular Medicine (AREA)
- Dermatology (AREA)
- Medical Informatics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Pulmonology (AREA)
- Magnetic Treatment Devices (AREA)
- Enzymes And Modification Thereof (AREA)
Abstract
Description
。
Claims (11)
- パルスパワー(Pulsed power)を発生させるパワー部と、
前記パルスパワーの提供を受けてパルス衝撃波を発生させるパルス衝撃波発生部と、
内部に液体及び前記パルス衝撃波発生部が配置される上部ハウジングと、
前記上部ハウジングと繋がっており、内部に薬物が配置される下部ハウジングと、
前記上部ハウジング及び前記下部ハウジングの間に提供され、前記上部ハウジングから発生する衝撃波を下部ハウジングに伝達する衝撃波伝達部と、
前記下部ハウジングに配置され、前記薬物を噴射する噴射部と、
を含むパルス衝撃波を利用した無針注射器。 - 前記パワー部は、
電圧と電流を供給する電源供給部と、
電源供給部から供給された電気を貯蔵する電気貯蔵部と、
電気貯蔵部から貯蔵された電気エネルギーをパルスパワーに印加させるスイッチと、
を含むことを特徴とする請求項1に記載のパルス衝撃波を利用した無針注射器。 - 前記パワー部は、
生成されたパルスの形成(form)を維持させる電気回路を更に含むことを特徴とする請求項2に記載のパルス衝撃波を利用した無針注射器。 - 前記パルス衝撃波発生部は、
パルスパワーの提供を受けて電流が流れる1つ以上の衝撃波発生電極と、
前記衝撃波発生電極のうちの1つ以上と近接し、衝撃波発生電極に接触又は非接触状態で配置される絶縁管と、
を含むことを特徴とする請求項1に記載のパルス衝撃波を利用した無針注射器。 - 前記パルス衝撃波発生部は、
前記電極の一端が前記絶縁管の外部に露出しないことを特徴とする請求項4に記載のパルス衝撃波を利用した無針注射器。 - 前記衝撃波発生電極は、
第1衝撃波発生電極と、
第2衝撃波発生電極とを含み、
前記絶縁管は、
前記第1衝撃波発生電極が内部に位置し、
前記第1衝撃波発生電極よりも長い第1絶縁管であることを特徴とする請求項4に記載のパルス衝撃波を利用した無針注射器。 - 前記絶縁管は、
前記第2衝撃波発生電極が内部に位置し、前記第2衝撃波発生電極よりも長い第2絶縁管を更に含むことを特徴とする請求項6に記載のパルス衝撃波を利用した無針注射器。 - 前記パルス衝撃波発生部は、
前記パワー部と衝撃波発生電極を連結するケーブルを含むことを特徴とする請求項1に記載のパルス衝撃波を利用した無針注射器。 - 前記衝撃波伝達部は、
前記パルス衝撃波発生部から生成されたバブルが前記上部ハウジングの内部の圧力を増加させると、
前記増加した圧力を前記下部ハウジングに伝達することを特徴とする請求項1に記載のパルス衝撃波を利用した無針注射器。 - 前記噴射部は、
前記下部ハウジングが前記上部ハウジングの内部の増加した圧力の伝達を受けると、薬物を噴射することを特徴とする請求項1に記載のパルス衝撃波を利用した無針注射器。 - 前記下部ハウジングに提供される前記薬物を貯蔵する薬物貯蔵部と、
前記薬物を前記薬物貯蔵部から前記下部ハウジングの方向にのみ伝達されるようにするチェックバルブと、
を更に含むことを特徴とする請求項1に記載のパルス衝撃波を利用した無針注射器。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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KR20200045256 | 2020-04-14 | ||
KR10-2020-0045256 | 2020-04-14 | ||
PCT/KR2021/003009 WO2021210785A1 (ko) | 2020-04-14 | 2021-03-11 | 펄스 충격파를 이용한 무침 주사기 |
Publications (2)
Publication Number | Publication Date |
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JP2023520935A true JP2023520935A (ja) | 2023-05-22 |
JP7494426B2 JP7494426B2 (ja) | 2024-06-04 |
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JP2022561502A Active JP7494426B2 (ja) | 2020-04-14 | 2021-03-11 | パルス衝撃波を利用した無針注射器 |
Country Status (7)
Country | Link |
---|---|
US (1) | US20230020863A1 (ja) |
EP (2) | EP4137179A4 (ja) |
JP (1) | JP7494426B2 (ja) |
KR (2) | KR102592451B1 (ja) |
CN (2) | CN115397491A (ja) |
IL (1) | IL297101A (ja) |
WO (1) | WO2021210785A1 (ja) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
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KR102565598B1 (ko) | 2021-11-08 | 2023-08-10 | 주식회사 엔스퀘어 | 약액 수용량의 조절이 가능한 마이크로젯 주입 장치 |
Citations (4)
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JP2006524120A (ja) * | 2003-04-21 | 2006-10-26 | ストラテージェント ライフ サイエンシズ | マイクロジェットで反復的に薬物を搬送する装置および方法 |
JP2014147924A (ja) * | 2012-03-02 | 2014-08-21 | Japan Science & Technology Agency | プラズマ気泡噴出部材、局所アブレーション装置及び局所アブレーション方法、並びに治癒装置及び治癒方法 |
KR20190127009A (ko) * | 2018-05-03 | 2019-11-13 | 한국기계연구원 | 유체의 급속 팽창에 의한 피스톤 구동 방식의 무침 주사 장치 |
KR20190128338A (ko) * | 2018-05-08 | 2019-11-18 | 서울대학교산학협력단 | 마이크로 버블 선 생성을 통해 분사 효율을 향상시킨 마이크로젯 분사 장치 |
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CA2331030A1 (en) * | 2000-02-16 | 2001-08-16 | Roche Diagnostics Gmbh | Hypodermic needleless injection system |
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DE102005062220B3 (de) * | 2005-12-20 | 2007-02-15 | Primojex Gmbh | System zur Injektion durch oder in die menschliche Haut |
CN102397621B (zh) * | 2011-08-24 | 2014-07-30 | 南京理工大学 | 封闭式激光冲击波透皮给药装置 |
US9138249B2 (en) * | 2012-08-17 | 2015-09-22 | Shockwave Medical, Inc. | Shock wave catheter system with arc preconditioning |
KR101424394B1 (ko) * | 2013-05-30 | 2014-07-28 | 서울대학교산학협력단 | 가압 수단을 구비한 마이크로젯 약물 전달 장치 |
JP2015108302A (ja) * | 2013-12-03 | 2015-06-11 | 国立大学法人 東京大学 | 液体噴射装置および液体噴射方法 |
EP3294384B1 (en) | 2015-05-10 | 2022-01-12 | Kolorpen Ltd. | Device and method for repetitive needleless injection |
KR101680562B1 (ko) * | 2015-09-14 | 2016-11-29 | 연세대학교 산학협력단 | 밀도-의존 가변형 니들을 구비하는 주사기 |
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KR20180087639A (ko) * | 2017-01-25 | 2018-08-02 | 이준욱 | 무 바늘 주사기구 및 이의 사용방법 |
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-
2021
- 2021-03-11 CN CN202180028225.6A patent/CN115397491A/zh active Pending
- 2021-03-11 IL IL297101A patent/IL297101A/en unknown
- 2021-03-11 EP EP21788767.8A patent/EP4137179A4/en active Pending
- 2021-03-11 JP JP2022561502A patent/JP7494426B2/ja active Active
- 2021-03-11 WO PCT/KR2021/003009 patent/WO2021210785A1/ko unknown
- 2021-04-13 KR KR1020210047692A patent/KR102592451B1/ko active IP Right Grant
- 2021-04-13 EP EP21789530.9A patent/EP4129364A4/en active Pending
- 2021-04-13 CN CN202180025208.7A patent/CN115361984A/zh active Pending
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2022
- 2022-09-29 US US17/936,649 patent/US20230020863A1/en active Pending
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2024
- 2024-03-05 KR KR1020240031158A patent/KR102670007B1/ko active IP Right Grant
Patent Citations (4)
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JP2006524120A (ja) * | 2003-04-21 | 2006-10-26 | ストラテージェント ライフ サイエンシズ | マイクロジェットで反復的に薬物を搬送する装置および方法 |
JP2014147924A (ja) * | 2012-03-02 | 2014-08-21 | Japan Science & Technology Agency | プラズマ気泡噴出部材、局所アブレーション装置及び局所アブレーション方法、並びに治癒装置及び治癒方法 |
KR20190127009A (ko) * | 2018-05-03 | 2019-11-13 | 한국기계연구원 | 유체의 급속 팽창에 의한 피스톤 구동 방식의 무침 주사 장치 |
KR20190128338A (ko) * | 2018-05-08 | 2019-11-18 | 서울대학교산학협력단 | 마이크로 버블 선 생성을 통해 분사 효율을 향상시킨 마이크로젯 분사 장치 |
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Publication number | Publication date |
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KR102592451B1 (ko) | 2023-10-23 |
US20230020863A1 (en) | 2023-01-19 |
EP4129364A4 (en) | 2023-09-06 |
EP4137179A4 (en) | 2023-09-06 |
CN115397491A (zh) | 2022-11-25 |
KR20240032812A (ko) | 2024-03-12 |
IL297101A (en) | 2022-12-01 |
JP7494426B2 (ja) | 2024-06-04 |
WO2021210785A1 (ko) | 2021-10-21 |
KR102670007B1 (ko) | 2024-05-28 |
CN115361984A (zh) | 2022-11-18 |
KR20210127632A (ko) | 2021-10-22 |
EP4129364A1 (en) | 2023-02-08 |
EP4137179A1 (en) | 2023-02-22 |
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