JP2023515795A5 - - Google Patents

Info

Publication number
JP2023515795A5
JP2023515795A5 JP2022549613A JP2022549613A JP2023515795A5 JP 2023515795 A5 JP2023515795 A5 JP 2023515795A5 JP 2022549613 A JP2022549613 A JP 2022549613A JP 2022549613 A JP2022549613 A JP 2022549613A JP 2023515795 A5 JP2023515795 A5 JP 2023515795A5
Authority
JP
Japan
Prior art keywords
aav
capsid protein
derivative
amino acid
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022549613A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023515795A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/018280 external-priority patent/WO2021167919A1/en
Publication of JP2023515795A publication Critical patent/JP2023515795A/ja
Publication of JP2023515795A5 publication Critical patent/JP2023515795A5/ja
Pending legal-status Critical Current

Links

JP2022549613A 2020-02-18 2021-02-17 Aavカプシド-プロモーター相互作用および細胞選択的遺伝子発現 Pending JP2023515795A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202062977838P 2020-02-18 2020-02-18
US62/977,838 2020-02-18
US202063023003P 2020-05-11 2020-05-11
US63/023,003 2020-05-11
PCT/US2021/018280 WO2021167919A1 (en) 2020-02-18 2021-02-17 Aav capsid-promoter interactions and cell selective gene expression

Publications (2)

Publication Number Publication Date
JP2023515795A JP2023515795A (ja) 2023-04-14
JP2023515795A5 true JP2023515795A5 (enExample) 2024-02-27

Family

ID=77391215

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022549613A Pending JP2023515795A (ja) 2020-02-18 2021-02-17 Aavカプシド-プロモーター相互作用および細胞選択的遺伝子発現

Country Status (7)

Country Link
US (1) US20230013145A1 (enExample)
EP (1) EP4107169A4 (enExample)
JP (1) JP2023515795A (enExample)
CN (1) CN115210248A (enExample)
AU (1) AU2021224551A1 (enExample)
CA (1) CA3164321A1 (enExample)
WO (1) WO2021167919A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20250206783A1 (en) * 2022-03-21 2025-06-26 Capsigen Inc. Transcription-dependent directed evolution of aav capsids having enhanced tropism
WO2023201306A1 (en) 2022-04-14 2023-10-19 Invisishield Technologies Ltd. Compositions for preventing or treating influenza infections
WO2025230969A1 (en) * 2024-05-02 2025-11-06 4D Molecular Therapeutics Inc. Aav variants with improved cns tropism and uses thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003221733A1 (en) * 2002-04-17 2003-11-03 University Of Florida Research Foundation, Inc. Improved raav vectors
US20060093589A1 (en) * 2004-02-19 2006-05-04 Warrington Kenneth H Vp2-modified raav vector compositions and uses therefor
CA2500523A1 (en) * 2003-05-01 2004-11-18 University Of Florida Research Foundation, Inc. Vp2-modified raav vector compositions and uses therefor
WO2010071454A1 (en) * 2008-12-17 2010-06-24 Auckland Uniservices Limited Adeno-associated viral vectors and uses thereof
LT3137497T (lt) * 2014-05-02 2021-07-26 Genzyme Corporation Aav vektoriai, skirti tinklainės ir cns genų terapijai
EP4344741A3 (en) * 2014-11-21 2024-08-28 The University of North Carolina at Chapel Hill Aav vectors targeted to the central nervous system

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