JP2023515675A5 - - Google Patents

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Publication number
JP2023515675A5
JP2023515675A5 JP2022552573A JP2022552573A JP2023515675A5 JP 2023515675 A5 JP2023515675 A5 JP 2023515675A5 JP 2022552573 A JP2022552573 A JP 2022552573A JP 2022552573 A JP2022552573 A JP 2022552573A JP 2023515675 A5 JP2023515675 A5 JP 2023515675A5
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JP
Japan
Application number
JP2022552573A
Other languages
Japanese (ja)
Other versions
JPWO2021178657A5 (https=
JP2023515675A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/020858 external-priority patent/WO2021178657A1/en
Publication of JP2023515675A publication Critical patent/JP2023515675A/ja
Publication of JPWO2021178657A5 publication Critical patent/JPWO2021178657A5/ja
Publication of JP2023515675A5 publication Critical patent/JP2023515675A5/ja
Pending legal-status Critical Current

Links

JP2022552573A 2020-03-05 2021-03-04 Pd-1アンタゴニスト、ctla4アンタゴニストおよびレンバチニブまたはその薬学的に許容される塩の組合せを用いる癌を治療する方法 Pending JP2023515675A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202062985500P 2020-03-05 2020-03-05
US62/985,500 2020-03-05
PCT/US2021/020858 WO2021178657A1 (en) 2020-03-05 2021-03-04 Methods for treating cancer using a combination of a pd-1 antagonist, a ctla4 antagonist, and lenvatinib or a pharmaceutically acceptable salt thereof

Publications (3)

Publication Number Publication Date
JP2023515675A JP2023515675A (ja) 2023-04-13
JPWO2021178657A5 JPWO2021178657A5 (https=) 2024-03-11
JP2023515675A5 true JP2023515675A5 (https=) 2024-03-11

Family

ID=77614229

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022552573A Pending JP2023515675A (ja) 2020-03-05 2021-03-04 Pd-1アンタゴニスト、ctla4アンタゴニストおよびレンバチニブまたはその薬学的に許容される塩の組合せを用いる癌を治療する方法

Country Status (6)

Country Link
US (1) US20230118596A1 (https=)
EP (1) EP4114464A4 (https=)
JP (1) JP2023515675A (https=)
KR (1) KR20220149740A (https=)
CN (1) CN115443152A (https=)
WO (1) WO2021178657A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2023003032A (es) * 2020-09-15 2023-06-01 Merck Sharp & Dohme Llc Terapia de combinacion de un antagonista de pd-1 y un antagonista de lag3 y lenvatinib o una sal farmaceuticamente aceptable del mismo para el tratamiento de pacientes con cancer.
WO2023160517A1 (zh) * 2022-02-22 2023-08-31 齐鲁制药有限公司 包含抗ctla4和抗pd1的混合抗体的药物组合物及其治疗用途
WO2024002074A1 (zh) * 2022-06-28 2024-01-04 齐鲁制药有限公司 包含抗ctla4和抗pd1的混合抗体的药物组合物及其治疗用途
EP4722358A1 (en) * 2023-06-02 2026-04-08 Ajou University Industry-Academic Cooperation Foundation Glycerol dehydratase variant and use thereof
AU2024311205A1 (en) * 2023-06-30 2026-01-22 Merck Sharp & Dohme Llc Treatment method and use of pharmaceutical combination containing conjugate

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20160093012A (ko) * 2013-11-05 2016-08-05 코그네이트 바이오서비시즈, 인코포레이티드 암 치료를 위한 체크포인트 억제제 및 치료제의 배합물
CN105296433B (zh) * 2014-08-01 2018-02-09 中山康方生物医药有限公司 一种ctla4抗体、其药物组合物及其用途
KR102662228B1 (ko) * 2015-03-04 2024-05-02 머크 샤프 앤드 돔 코포레이션 암을 치료하기 위한 pd-1 길항제 및 vegfr/fgfr/ret 티로신 키나제 억제제의 조합
TN2017000440A1 (en) * 2015-04-17 2019-04-12 Bristol Myers Squibb Co Compositions comprising a combination of an anti-pd-1 antibody and another antibody
CN110505882A (zh) * 2017-03-31 2019-11-26 默沙东公司 用pd-1的拮抗剂和抗ctla4抗体的组合治疗癌症的组合物和方法
SG11201910134SA (en) * 2017-05-02 2019-11-28 Merck Sharp & Dohme Stable formulations of anti-ctla4 antibodies alone and in combination with programmed death receptor 1 (pd-1) antibodies and methods of use thereof
EP3752193A4 (en) * 2018-02-13 2022-02-23 Merck Sharp & Dohme Corp. METHODS OF TREATMENT OF CANCER WITH ANTI-PD-1 ANTIBODIES AND ANTI-CTLA4 ANTIBODIES
EP3793557A1 (en) * 2018-05-14 2021-03-24 Merck Sharp & Dohme Corp. Biomarkers for a combination therapy comprising lenvatinib and a pd-1 antagonist
WO2021023117A1 (zh) * 2019-08-02 2021-02-11 康方药业有限公司 抗ctla4-抗pd-1双特异性抗体及其用途

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