JP2023515675A5 - - Google Patents

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Publication number
JP2023515675A5
JP2023515675A5 JP2022552573A JP2022552573A JP2023515675A5 JP 2023515675 A5 JP2023515675 A5 JP 2023515675A5 JP 2022552573 A JP2022552573 A JP 2022552573A JP 2022552573 A JP2022552573 A JP 2022552573A JP 2023515675 A5 JP2023515675 A5 JP 2023515675A5
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JP
Japan
Prior art keywords
pharmaceutical composition
kit
use according
administered
human
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022552573A
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English (en)
Japanese (ja)
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JP2023515675A (ja
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Application filed filed Critical
Priority claimed from PCT/US2021/020858 external-priority patent/WO2021178657A1/en
Publication of JP2023515675A publication Critical patent/JP2023515675A/ja
Publication of JP2023515675A5 publication Critical patent/JP2023515675A5/ja
Pending legal-status Critical Current

Links

JP2022552573A 2020-03-05 2021-03-04 Pd-1アンタゴニスト、ctla4アンタゴニストおよびレンバチニブまたはその薬学的に許容される塩の組合せを用いる癌を治療する方法 Pending JP2023515675A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202062985500P 2020-03-05 2020-03-05
US62/985,500 2020-03-05
PCT/US2021/020858 WO2021178657A1 (en) 2020-03-05 2021-03-04 Methods for treating cancer using a combination of a pd-1 antagonist, a ctla4 antagonist, and lenvatinib or a pharmaceutically acceptable salt thereof

Publications (2)

Publication Number Publication Date
JP2023515675A JP2023515675A (ja) 2023-04-13
JP2023515675A5 true JP2023515675A5 (https=) 2024-03-11

Family

ID=77614229

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022552573A Pending JP2023515675A (ja) 2020-03-05 2021-03-04 Pd-1アンタゴニスト、ctla4アンタゴニストおよびレンバチニブまたはその薬学的に許容される塩の組合せを用いる癌を治療する方法

Country Status (6)

Country Link
US (1) US20230118596A1 (https=)
EP (1) EP4114464A4 (https=)
JP (1) JP2023515675A (https=)
KR (1) KR20220149740A (https=)
CN (1) CN115443152A (https=)
WO (1) WO2021178657A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2021344849A1 (en) * 2020-09-15 2023-05-25 Eisai R&D Management Co., Ltd. Combination therapy of a pd-1 antagonist and lag3 antagonist and lenvatinib or a pharmaceutically acceptable salt thereof for treating patients with cancer
CN118660720A (zh) * 2022-02-22 2024-09-17 齐鲁制药有限公司 包含抗ctla4和抗pd1的混合抗体的药物组合物及其治疗用途
US20250376525A1 (en) * 2022-06-28 2025-12-11 Qilu Pharmaceutical Co., Ltd. Pharmaceutical composition comprising mixed antibody of anti-ctla4 and anti-pd1 and therapeutic use thereof
WO2024248535A1 (ko) * 2023-06-02 2024-12-05 아주대학교산학협력단 글리세롤 탈수효소 변이체 및 이의 용도
KR20260047513A (ko) * 2023-06-30 2026-04-08 머크 샤프 앤드 돔 엘엘씨 접합체를 포함하는 제약 조합물의 치료방법 및 용도

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL292510A (en) * 2013-11-05 2022-06-01 Cognate Bioservices Inc Combinations of checkpoint inhibitors and therapeutics to treat cancer
CN105296433B (zh) * 2014-08-01 2018-02-09 中山康方生物医药有限公司 一种ctla4抗体、其药物组合物及其用途
KR102662228B1 (ko) * 2015-03-04 2024-05-02 머크 샤프 앤드 돔 코포레이션 암을 치료하기 위한 pd-1 길항제 및 vegfr/fgfr/ret 티로신 키나제 억제제의 조합
KR20250004095A (ko) * 2015-04-17 2025-01-07 브리스톨-마이어스 스큅 컴퍼니 항-pd-1 항체 및 또 다른 항체의 조합물을 포함하는 조성물
WO2018183408A1 (en) * 2017-03-31 2018-10-04 Merck Sharp & Dohme Corp. Compositions and methods for treating cancer with a combination of an antagonist of pd-1 and an anti-ctla4 antibody
JP2020518598A (ja) * 2017-05-02 2020-06-25 メルク・シャープ・アンド・ドーム・コーポレーションMerck Sharp & Dohme Corp. 単独およびプログラム死受容体1(pd−1)抗体と組み合わされた抗ctla4抗体の安定な製剤、ならびにその使用方法
JP2021513540A (ja) * 2018-02-13 2021-05-27 メルク・シャープ・アンド・ドーム・コーポレーションMerck Sharp & Dohme Corp. 抗pd−1抗体及び抗ctla4抗体によるがんの処置方法
EP3793557A1 (en) * 2018-05-14 2021-03-24 Merck Sharp & Dohme Corp. Biomarkers for a combination therapy comprising lenvatinib and a pd-1 antagonist
WO2021023117A1 (zh) * 2019-08-02 2021-02-11 康方药业有限公司 抗ctla4-抗pd-1双特异性抗体及其用途

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