JP2023514594A5 - - Google Patents

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Publication number
JP2023514594A5
JP2023514594A5 JP2022549303A JP2022549303A JP2023514594A5 JP 2023514594 A5 JP2023514594 A5 JP 2023514594A5 JP 2022549303 A JP2022549303 A JP 2022549303A JP 2022549303 A JP2022549303 A JP 2022549303A JP 2023514594 A5 JP2023514594 A5 JP 2023514594A5
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JP
Japan
Prior art keywords
mirna
composition according
orf
composition
target sequences
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Application number
JP2022549303A
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English (en)
Japanese (ja)
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JP2023514594A (ja
JP7539723B2 (ja
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Priority claimed from PCT/US2021/019028 external-priority patent/WO2021168405A1/en
Publication of JP2023514594A publication Critical patent/JP2023514594A/ja
Publication of JP2023514594A5 publication Critical patent/JP2023514594A5/ja
Application granted granted Critical
Publication of JP7539723B2 publication Critical patent/JP7539723B2/ja
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JP2022549303A 2020-02-21 2021-02-22 コード化リボ核酸の器官保護発現及び調節のための組成物並びに方法 Active JP7539723B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202062979619P 2020-02-21 2020-02-21
US62/979,619 2020-02-21
US202063059458P 2020-07-31 2020-07-31
US63/059,458 2020-07-31
PCT/US2021/019028 WO2021168405A1 (en) 2020-02-21 2021-02-22 Compositions and methods for organ-protective expression and modulation of coding ribonucleic acids

Publications (3)

Publication Number Publication Date
JP2023514594A JP2023514594A (ja) 2023-04-06
JP2023514594A5 true JP2023514594A5 (https=) 2024-03-01
JP7539723B2 JP7539723B2 (ja) 2024-08-26

Family

ID=77391786

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022549303A Active JP7539723B2 (ja) 2020-02-21 2021-02-22 コード化リボ核酸の器官保護発現及び調節のための組成物並びに方法

Country Status (11)

Country Link
US (4) US11596685B2 (https=)
EP (1) EP4106770A4 (https=)
JP (1) JP7539723B2 (https=)
KR (2) KR102838785B1 (https=)
CN (1) CN115297868B (https=)
AU (2) AU2021224990B2 (https=)
CA (1) CA3168048A1 (https=)
IL (1) IL295724A (https=)
MX (1) MX2022010084A (https=)
WO (1) WO2021168405A1 (https=)
ZA (1) ZA202208795B (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201714430D0 (en) * 2017-09-07 2017-10-25 Micol Romain Compositions and processes for targeted delivery and expression and modulation of therapeutic components in tissue
EP4065600A1 (en) 2019-11-25 2022-10-05 Cornell University Apoe gene therapy
CN113583977B (zh) * 2020-04-30 2025-06-06 杭州康万达医药科技有限公司 可受微小rna调控的分离的重组溶瘤痘病毒及其应用
MX2023001187A (es) * 2020-07-31 2023-04-04 Combined Therapeutics Inc Composiciones y métodos para una vacunación mejorada.
CN116445492A (zh) * 2022-01-10 2023-07-18 北京锦篮基因科技有限公司 用于x染色体连锁肾上腺脑白质营养不良的基因治疗药物和方法
CN114874999B (zh) * 2022-04-22 2023-04-21 中国医学科学院病原生物学研究所 一种基于痘苗病毒载体的新型冠状病毒病毒样颗粒疫苗
CN116004628B (zh) * 2023-01-03 2024-07-19 苏州大学 一种预防或治疗慢性疼痛的miRNA靶点及其应用
CN117530932B (zh) * 2024-01-08 2024-04-26 中国药科大学 一种抑制肿瘤生长及肺转移的人工外泌体及其应用
WO2025251079A1 (en) * 2024-05-31 2025-12-04 University Of Massachusetts Rna compositions and methods of use thereof in the treatment of cancer

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7683036B2 (en) 2003-07-31 2010-03-23 Regulus Therapeutics Inc. Oligomeric compounds and compositions for use in modulation of small non-coding RNAs
WO2009012263A2 (en) 2007-07-18 2009-01-22 The Trustees Of Columbia University In The City Of New York Tissue-specific micrornas and compositions and uses thereof
US7993831B2 (en) * 2007-09-14 2011-08-09 Asuragen, Inc. Methods of normalization in microRNA detection assays
WO2010126766A1 (en) * 2009-04-30 2010-11-04 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Inducible interleukin-12
CA3018046A1 (en) 2011-12-16 2013-06-20 Moderna Therapeutics, Inc. Modified nucleoside, nucleotide, and nucleic acid compositions
CN108474003A (zh) 2015-11-20 2018-08-31 俄勒冈健康与科学大学 包含微小rna识别元件的cmv载体
SI3458083T1 (sl) * 2016-05-18 2023-03-31 Modernatx, Inc. Polinukleotidi, ki kodirajo interlevkin-12 (IL12) in njihova uporaba
CN110402145A (zh) * 2016-10-26 2019-11-01 莫得纳特斯公司 用于增强免疫应答的信使核糖核酸及其使用方法
WO2018115527A2 (en) * 2016-12-23 2018-06-28 Curevac Ag Mers coronavirus vaccine
GB201714430D0 (en) 2017-09-07 2017-10-25 Micol Romain Compositions and processes for targeted delivery and expression and modulation of therapeutic components in tissue
EP4008333A1 (en) * 2018-02-19 2022-06-08 Combined Therapeutics, Inc. Compositions and methods for organ-protective expression and modulation of coding ribonucleic acids
EP3986447A4 (en) * 2019-06-18 2023-08-16 Citranvi Biosciences, LLC RATIONALLY MANIPULATED CARRIER PROTEINS FOR VACCINES
GB2594683A (en) * 2020-02-17 2021-11-10 Vaxbio Ltd Vaccine

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