JP2023513158A5 - - Google Patents

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Publication number
JP2023513158A5
JP2023513158A5 JP2022547675A JP2022547675A JP2023513158A5 JP 2023513158 A5 JP2023513158 A5 JP 2023513158A5 JP 2022547675 A JP2022547675 A JP 2022547675A JP 2022547675 A JP2022547675 A JP 2022547675A JP 2023513158 A5 JP2023513158 A5 JP 2023513158A5
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JP
Japan
Prior art keywords
antibody
cancer
antigen
cell
syndrome
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JP2022547675A
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English (en)
Japanese (ja)
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JP2023513158A (ja
JP7767291B2 (ja
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Priority claimed from PCT/US2021/015362 external-priority patent/WO2021158413A1/en
Publication of JP2023513158A publication Critical patent/JP2023513158A/ja
Publication of JP2023513158A5 publication Critical patent/JP2023513158A5/ja
Application granted granted Critical
Publication of JP7767291B2 publication Critical patent/JP7767291B2/ja
Active legal-status Critical Current
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JP2022547675A 2020-02-05 2021-01-28 新規のlilrb2抗体およびその使用 Active JP7767291B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202062970496P 2020-02-05 2020-02-05
US62/970,496 2020-02-05
PCT/US2021/015362 WO2021158413A1 (en) 2020-02-05 2021-01-28 Novel lilrb2 antibodies and uses thereof

Publications (3)

Publication Number Publication Date
JP2023513158A JP2023513158A (ja) 2023-03-30
JP2023513158A5 true JP2023513158A5 (https=) 2024-02-06
JP7767291B2 JP7767291B2 (ja) 2025-11-11

Family

ID=77199417

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022547675A Active JP7767291B2 (ja) 2020-02-05 2021-01-28 新規のlilrb2抗体およびその使用

Country Status (9)

Country Link
US (1) US12596122B2 (https=)
EP (1) EP4100439A4 (https=)
JP (1) JP7767291B2 (https=)
KR (1) KR20220137032A (https=)
CN (1) CN115768793A (https=)
AU (1) AU2021216361A1 (https=)
BR (1) BR112022015450A2 (https=)
CA (1) CA3165532A1 (https=)
WO (1) WO2021158413A1 (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11680101B2 (en) 2017-01-27 2023-06-20 Kymab Limited Anti-OPG antibodies
FI3661935T3 (fi) 2017-08-11 2023-01-13 Kinaasin estäjinä käyttökelpoiset pyratsolipyrimidiinit
WO2023039613A2 (en) * 2021-09-13 2023-03-16 The Board Of Regents Of The University Of Texas System Lilrb2-specific monoclonal antibodies and methods of their use
EP4486383A2 (en) * 2022-03-04 2025-01-08 D2M Biotherapeutics Limited Anti-lilrb1/2 antibodies and uses thereof
CN116333127B (zh) * 2022-06-28 2026-03-24 北京科诺信诚科技有限公司 靶向人lilrb2的纳米抗体及其应用
TW202409088A (zh) * 2022-07-08 2024-03-01 中國商科望(蘇州)生物醫藥科技有限公司 抗lilrb2抗體及其用途
CN119604531A (zh) * 2022-07-29 2025-03-11 盛禾(中国)生物制药有限公司 一种抗ilt4的单域抗体及其应用
CN115044549B (zh) * 2022-08-12 2023-02-07 北京科途医学科技有限公司 用于保持免疫细胞多样性的培养基和细胞组合物的培养方法
CN119768432A (zh) * 2022-08-22 2025-04-04 德琪(杭州)生物有限公司 新颖的抗lilrb2抗体和其用途
EP4491230A1 (en) * 2023-07-14 2025-01-15 iOmx Therapeutics AG Cross-specific antigen binding proteins (abp) targeting leukocyte immunoglobulin-like receptor subfamily b1 (lilrb1) and lilrb2, combinations and uses thereof
AU2023410277A1 (en) * 2022-12-23 2025-06-12 Iomx Therapeutics Ag Cross-specific antigen binding proteins (abp) targeting leukocyte immunoglobulin-like receptor subfamily b1 (lilrb1) and lilrb2, combinations and uses thereof
CN119176874A (zh) * 2023-06-21 2024-12-24 康源博创生物科技(北京)有限公司 一种能够结合lilrb2的抗体或其抗原结合片段
CN116874600B (zh) * 2023-07-13 2024-07-05 浙江大学 来自纳米抗体可靶向cd163受体的短肽的制备方法及其应用
CN117343346B (zh) * 2023-12-04 2024-03-08 内蒙古大学 可视化识别盐酸克仑特罗的超灵敏铕基MOFs传感器及制备方法和用途
WO2025232879A1 (en) * 2024-05-10 2025-11-13 Cytocares (Shanghai) Inc. Anti-lilrb2 monospecific and bispecific antibody constructs and uses thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997002479A2 (en) 1995-06-30 1997-01-23 Yale University Human monoclonal anti-tumor antibodies
US20150174203A1 (en) * 2012-05-30 2015-06-25 Icahn School Of Medicine At Mount Sinai Compositions And Methods For Modulating Pro-Inflammatory Immune Response
KR20180016972A (ko) * 2015-02-22 2018-02-20 소렌토 쎄라퓨틱스, 인코포레이티드 Cd137에 결합하는 항체 치료제
US11680101B2 (en) * 2017-01-27 2023-06-20 Kymab Limited Anti-OPG antibodies
TWI796329B (zh) * 2017-04-07 2023-03-21 美商默沙東有限責任公司 抗-ilt4抗體及抗原結合片段
EA202091540A1 (ru) 2017-12-22 2021-03-22 Джаунс Терапьютикс, Инк. Антитела к lilrb2
CN113056483B (zh) * 2018-07-09 2025-08-01 戊瑞治疗有限公司 结合到ilt4的抗体

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