JP2023510289A - ワクチン送達のための自己組織化自己アジュバント系 - Google Patents

ワクチン送達のための自己組織化自己アジュバント系 Download PDF

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JP2023510289A
JP2023510289A JP2022542050A JP2022542050A JP2023510289A JP 2023510289 A JP2023510289 A JP 2023510289A JP 2022542050 A JP2022542050 A JP 2022542050A JP 2022542050 A JP2022542050 A JP 2022542050A JP 2023510289 A JP2023510289 A JP 2023510289A
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immunogenic
peptide
immunogenic agent
agent
hydrophobic
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JP2023510289A5 (https=
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イストヴァン トス
マリウスズ スクワルチンスキ
グアンズー チャオ
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ザ ユニバーシティー オブ クイーンズランド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/215—Coronaviridae, e.g. avian infectious bronchitis virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/385—Haptens or antigens, bound to carriers
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0003—Invertebrate antigens
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092—Streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
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    • A61P31/20—Antivirals for DNA viruses
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    • A61P35/00—Antineoplastic agents
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    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/01—DNA viruses
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    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/08—RNA viruses
    • C07K14/165—Coronaviridae, e.g. avian infectious bronchitis virus
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    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
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    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55516—Proteins; Peptides
    • A—HUMAN NECESSITIES
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    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
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    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/575—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
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    • A61K2039/6031—Proteins
    • A61K2039/605—MHC molecules or ligands thereof
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    • A61K2039/627—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier characterised by the linker
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43536—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from worms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K2319/00—Fusion polypeptide
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    • C07K2319/00—Fusion polypeptide
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/735—Fusion polypeptide containing domain for protein-protein interaction containing a domain for self-assembly, e.g. a viral coat protein (includes phage display)
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    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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JP2022542050A 2020-01-09 2021-01-08 ワクチン送達のための自己組織化自己アジュバント系 Pending JP2023510289A (ja)

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Application Number Priority Date Filing Date Title
AU2020900058 2020-01-09
AU2020900058A AU2020900058A0 (en) 2020-01-09 Self-assembling, self-adjuvanting system for delivery of vaccines
PCT/AU2021/050012 WO2021138721A1 (en) 2020-01-09 2021-01-08 Self-assembling, self-adjuvanting system for delivery of vaccines

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JP2023510289A true JP2023510289A (ja) 2023-03-13
JP2023510289A5 JP2023510289A5 (https=) 2024-01-09

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US (1) US20230090311A1 (https=)
EP (1) EP4087606A1 (https=)
JP (1) JP2023510289A (https=)
AU (1) AU2021205866A1 (https=)
CA (1) CA3163999A1 (https=)
WO (1) WO2021138721A1 (https=)

Families Citing this family (3)

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Publication number Priority date Publication date Assignee Title
PH12021050442A1 (en) * 2021-08-13 2023-06-05 Univ Of The Philippines Through The Univ Of The Philippines Manila ANTIPEPTIDE IMMUNOGLOBULINS TO SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 (SARS-CoV-2) SPIKE GLYCOPROTEIN (S PROTEIN) EPITOPES AND COGNATE IMMUNOGENS, METHODS FOR PRODUCING AND UTILIZING THE SAME, AND ANTIGEN DETECTION SYSTEMS RELATING THERETO
US20240139312A1 (en) * 2022-05-27 2024-05-02 Design-Zyme LLC Universal adjuvant for nasal, oral, and intramuscular delivery of vaccines
US20240156958A1 (en) * 2022-11-02 2024-05-16 Design-Zyme LLC Self-adjuvanting multi-protein complexes for modular vaccine production

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018500389A (ja) * 2014-12-10 2018-01-11 華西亞生醫有限公司 効率的な抗体産生のための免疫化に使用される新規なタンパク質構造
WO2018187515A1 (en) * 2017-04-04 2018-10-11 Avidea Technologies, Inc. Peptide-based vaccines, methods of manufacturing, and uses thereof for inducing an immune response
WO2019031446A1 (ja) * 2017-08-07 2019-02-14 国立大学法人東京農工大学 抗原組成物
WO2019226828A2 (en) * 2018-05-22 2019-11-28 Avidea Technologies, Inc. Improved methods of manufacturing peptide-based vaccines

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111983226A (zh) * 2020-03-25 2020-11-24 新加坡国立大学 SARSr-CoV抗体的检测
KR20250107297A (ko) * 2020-04-02 2025-07-11 리제너론 파아마슈티컬스, 인크. 항-sars-cov-2 스파이크 당단백질 항체 및 항원-결합 단편

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018500389A (ja) * 2014-12-10 2018-01-11 華西亞生醫有限公司 効率的な抗体産生のための免疫化に使用される新規なタンパク質構造
WO2018187515A1 (en) * 2017-04-04 2018-10-11 Avidea Technologies, Inc. Peptide-based vaccines, methods of manufacturing, and uses thereof for inducing an immune response
WO2019031446A1 (ja) * 2017-08-07 2019-02-14 国立大学法人東京農工大学 抗原組成物
WO2019226828A2 (en) * 2018-05-22 2019-11-28 Avidea Technologies, Inc. Improved methods of manufacturing peptide-based vaccines

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BEILSTEIN J.ORG.CHEM., vol. 10, JPN6025000615, 2014, pages 1741 - 1748, ISSN: 0005661229 *
MED.CHEM.LETT., vol. 10, JPN6025000617, 2019, pages 1253 - 1259, ISSN: 0005661228 *
MOL.PHARMACEUTICS, vol. 14, JPN6025000616, 2017, pages 1482 - 1493, ISSN: 0005661227 *

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EP4087606A1 (en) 2022-11-16
CA3163999A1 (en) 2021-07-15
US20230090311A1 (en) 2023-03-23
WO2021138721A1 (en) 2021-07-15

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