JP2023502625A5 - - Google Patents
Info
- Publication number
- JP2023502625A5 JP2023502625A5 JP2022527937A JP2022527937A JP2023502625A5 JP 2023502625 A5 JP2023502625 A5 JP 2023502625A5 JP 2022527937 A JP2022527937 A JP 2022527937A JP 2022527937 A JP2022527937 A JP 2022527937A JP 2023502625 A5 JP2023502625 A5 JP 2023502625A5
- Authority
- JP
- Japan
- Prior art keywords
- hla
- peptide
- ras
- molecule
- mutation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025140331A JP2025176716A (ja) | 2019-11-15 | 2025-08-26 | 共有新抗原を標的にする抗原結合タンパク質 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962936303P | 2019-11-15 | 2019-11-15 | |
| US62/936,303 | 2019-11-15 | ||
| US202063030774P | 2020-05-27 | 2020-05-27 | |
| US63/030,774 | 2020-05-27 | ||
| PCT/US2020/060605 WO2021097365A2 (en) | 2019-11-15 | 2020-11-13 | Antigen-binding proteins targeting shared neoantigens |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025140331A Division JP2025176716A (ja) | 2019-11-15 | 2025-08-26 | 共有新抗原を標的にする抗原結合タンパク質 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023502625A JP2023502625A (ja) | 2023-01-25 |
| JP2023502625A5 true JP2023502625A5 (https=) | 2023-11-21 |
Family
ID=75912393
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022527937A Pending JP2023502625A (ja) | 2019-11-15 | 2020-11-13 | 共有新抗原を標的にする抗原結合タンパク質 |
| JP2025140331A Pending JP2025176716A (ja) | 2019-11-15 | 2025-08-26 | 共有新抗原を標的にする抗原結合タンパク質 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025140331A Pending JP2025176716A (ja) | 2019-11-15 | 2025-08-26 | 共有新抗原を標的にする抗原結合タンパク質 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20230041030A1 (https=) |
| EP (1) | EP4058484A4 (https=) |
| JP (2) | JP2023502625A (https=) |
| KR (1) | KR20220098379A (https=) |
| CN (1) | CN115175934A (https=) |
| AU (1) | AU2020384374A1 (https=) |
| CA (1) | CA3157411A1 (https=) |
| IL (1) | IL292535A (https=) |
| WO (1) | WO2021097365A2 (https=) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LT3428194T (lt) | 2017-07-14 | 2021-12-10 | Immatics Biotechnologies Gmbh | Pagerinta dvejopo savitumo polipeptido molekulė |
| WO2020154617A1 (en) * | 2019-01-25 | 2020-07-30 | The Trustees Of The University Of Pennsylvania | Compositions and methods for targeting mutant ras |
| CN114026116A (zh) * | 2019-02-20 | 2022-02-08 | 弗雷德哈钦森癌症研究中心 | Ras新抗原特异性结合蛋白及其用途 |
| WO2022233956A1 (en) | 2021-05-05 | 2022-11-10 | Immatics Biotechnologies Gmbh | Antigen binding proteins specifically binding prame |
| EP4370540A2 (en) * | 2021-07-12 | 2024-05-22 | Ludwig Institute for Cancer Research Ltd | T cell receptors specific for tumor-associated antigens and methods of use thereof |
| IL311258A (en) * | 2021-09-17 | 2024-05-01 | Gritstone Bio Inc | Kras neoantigen therapies |
| US20240390423A1 (en) * | 2021-10-29 | 2024-11-28 | Yafei Hou | T cell receptor recognizing s37f mutation in ctnnb1 and its application |
| WO2023086435A1 (en) * | 2021-11-10 | 2023-05-19 | Memorial Sloan-Kettering Cancer Center | T cell receptors targeting q61-comprising ras mutations and uses thereof |
| JP2025504883A (ja) * | 2022-01-21 | 2025-02-19 | テ－クニフェ ゲーエムベーハー | 決定可能な親和性で特定のペプチドを結合する抗原認識コンストラクト、およびｋｒａｓに抗原特異性を有するｔ細胞レセプター、ならびに、対応する核酸配列、ベクター、宿主細胞、医薬組成物、およびキット |
| WO2023173024A2 (en) * | 2022-03-10 | 2023-09-14 | The Board Of Trustees Of The Leland Stanford Junior University | Treatment of coronary artery disease by reducing activity of cross-reactive t cells |
| WO2024036166A1 (en) * | 2022-08-08 | 2024-02-15 | The University Of North Carolina At Chapel Hill | Bioorthogonal t cell receptor molecules and methods of making and using the same |
| WO2024039576A2 (en) * | 2022-08-19 | 2024-02-22 | Memorial Sloan-Kettering Cancer Center | T cell receptors targeting ras mutations and uses thereof |
| AU2024228388A1 (en) * | 2023-02-27 | 2025-10-02 | Adaptive Biotechnologies Corp. | Therapeutic t cell receptors targeting kras g12d |
| CN116350758B (zh) * | 2023-03-16 | 2024-08-06 | 郑州大学 | 肿瘤共享新抗原表位肽或其编码核酸在制备药物中的应用 |
| CN118909132A (zh) * | 2023-05-06 | 2024-11-08 | 北京鼎成肽源生物技术有限公司 | 靶向kras g12v突变的tcr分子和细胞及其应用 |
| IL304887A (en) * | 2023-07-31 | 2025-02-01 | Yeda Res & Dev | T-cell receptor directed against RAS neoantigen |
| WO2025056659A1 (en) * | 2023-09-15 | 2025-03-20 | Medigene Immunotherapies Gmbh | T-CELL RECEPTOR VARIANT AGAINST mKRAS7-16 G12V AND G12C |
| WO2025056656A1 (en) * | 2023-09-15 | 2025-03-20 | Medigene Immunotherapies Gmbh | T-CELL RECEPTOR VARIANT AGAINST mKRAS7-16 G12V |
| WO2025189363A1 (zh) * | 2024-03-12 | 2025-09-18 | 广州医科大学 | 一种t细胞受体(tcr)及其用途 |
| WO2025240737A1 (en) * | 2024-05-16 | 2025-11-20 | Rutgers, The State University Of New Jersey | Methods of producing memory t cells in vitro and their use in immunotherapy |
| WO2025259799A2 (en) * | 2024-06-12 | 2025-12-18 | Biontech Us Inc. | T cell receptor compositions and methods of use thereof |
| EP4737476A1 (en) * | 2024-09-12 | 2026-05-06 | Medigene Immunotherapies GmbH | T-cell receptor variant against mkras 7-16 g12d |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013040142A2 (en) * | 2011-09-16 | 2013-03-21 | Iogenetics, Llc | Bioinformatic processes for determination of peptide binding |
| WO2013190090A1 (en) * | 2012-06-21 | 2013-12-27 | Philip Morris Products S.A. | Gene signatures for classifying and grading lung cancer |
| CN118994363A (zh) * | 2014-11-26 | 2024-11-22 | 美国卫生和人力服务部 | 抗突变的kras的t细胞受体 |
| WO2016154047A2 (en) * | 2015-03-20 | 2016-09-29 | Memorial Sloan-Kettering Cancer Center | Monoclonal antigen-binding proteins to intracellular oncogene products |
| WO2016154246A1 (en) * | 2015-03-23 | 2016-09-29 | The Johns Hopkins University | Hla-restricted epitopes encoded by somatically mutated genes |
| IL294183B2 (en) * | 2015-05-20 | 2023-10-01 | Dana Farber Cancer Inst Inc | shared neoantigens |
| TW201702272A (zh) * | 2015-05-22 | 2017-01-16 | 美國紀念斯隆 凱特琳癌症中心 | Ｐｒａｍｅ肽專一性類ｔ細胞受體抗體 |
| US20210147550A1 (en) * | 2017-08-18 | 2021-05-20 | Joshua Michael Francis | Antigen-binding proteins targeting shared antigens |
| AU2019275072A1 (en) * | 2018-05-23 | 2021-01-21 | Seattle Project Corp. | Shared antigens |
-
2020
- 2020-11-13 KR KR1020227019577A patent/KR20220098379A/ko active Pending
- 2020-11-13 CA CA3157411A patent/CA3157411A1/en active Pending
- 2020-11-13 CN CN202080085181.6A patent/CN115175934A/zh active Pending
- 2020-11-13 AU AU2020384374A patent/AU2020384374A1/en active Pending
- 2020-11-13 JP JP2022527937A patent/JP2023502625A/ja active Pending
- 2020-11-13 WO PCT/US2020/060605 patent/WO2021097365A2/en not_active Ceased
- 2020-11-13 EP EP20886309.2A patent/EP4058484A4/en active Pending
- 2020-11-13 IL IL292535A patent/IL292535A/en unknown
-
2022
- 2022-05-13 US US17/744,354 patent/US20230041030A1/en active Pending
-
2025
- 2025-08-26 JP JP2025140331A patent/JP2025176716A/ja active Pending
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