JP2023166406A5 - - Google Patents
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- Publication number
- JP2023166406A5 JP2023166406A5 JP2023131860A JP2023131860A JP2023166406A5 JP 2023166406 A5 JP2023166406 A5 JP 2023166406A5 JP 2023131860 A JP2023131860 A JP 2023131860A JP 2023131860 A JP2023131860 A JP 2023131860A JP 2023166406 A5 JP2023166406 A5 JP 2023166406A5
- Authority
- JP
- Japan
- Prior art keywords
- demand
- hae
- attack
- treatment
- acute
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025084646A JP2025124716A (ja) | 2019-06-14 | 2025-05-21 | 遺伝性血管性浮腫の治療 |
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962861725P | 2019-06-14 | 2019-06-14 | |
| US62/861,725 | 2019-06-14 | ||
| GB1910116.1 | 2019-07-15 | ||
| GBGB1910116.1A GB201910116D0 (en) | 2019-07-15 | 2019-07-15 | Treatments of hereditary angioedema |
| PCT/GB2020/051439 WO2020249977A1 (en) | 2019-06-14 | 2020-06-15 | Treatments of hereditary angioedema |
| JP2021571931A JP7356518B2 (ja) | 2019-06-14 | 2020-06-15 | 遺伝性血管性浮腫の治療 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021571931A Division JP7356518B2 (ja) | 2019-06-14 | 2020-06-15 | 遺伝性血管性浮腫の治療 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025084646A Division JP2025124716A (ja) | 2019-06-14 | 2025-05-21 | 遺伝性血管性浮腫の治療 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023166406A JP2023166406A (ja) | 2023-11-21 |
| JP2023166406A5 true JP2023166406A5 (https=) | 2024-04-23 |
| JP7688078B2 JP7688078B2 (ja) | 2025-06-03 |
Family
ID=67700145
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021571931A Active JP7356518B2 (ja) | 2019-06-14 | 2020-06-15 | 遺伝性血管性浮腫の治療 |
| JP2023131860A Active JP7688078B2 (ja) | 2019-06-14 | 2023-08-14 | 遺伝性血管性浮腫の治療 |
| JP2025084646A Pending JP2025124716A (ja) | 2019-06-14 | 2025-05-21 | 遺伝性血管性浮腫の治療 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021571931A Active JP7356518B2 (ja) | 2019-06-14 | 2020-06-15 | 遺伝性血管性浮腫の治療 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025084646A Pending JP2025124716A (ja) | 2019-06-14 | 2025-05-21 | 遺伝性血管性浮腫の治療 |
Country Status (34)
| Country | Link |
|---|---|
| US (1) | US20220218680A1 (https=) |
| EP (2) | EP4282474A3 (https=) |
| JP (3) | JP7356518B2 (https=) |
| KR (1) | KR102748728B1 (https=) |
| CN (1) | CN114126612A (https=) |
| AR (1) | AR119158A1 (https=) |
| AU (1) | AU2020293614B2 (https=) |
| BR (1) | BR112021024664A2 (https=) |
| CA (1) | CA3142218A1 (https=) |
| CL (2) | CL2021003244A1 (https=) |
| DK (1) | DK3982960T3 (https=) |
| EA (1) | EA202193019A1 (https=) |
| ES (1) | ES2956471T3 (https=) |
| FI (1) | FI3982960T3 (https=) |
| GB (1) | GB201910116D0 (https=) |
| HR (1) | HRP20230696T1 (https=) |
| HU (1) | HUE063163T2 (https=) |
| IL (1) | IL288615A (https=) |
| LT (1) | LT3982960T (https=) |
| MA (1) | MA56187B1 (https=) |
| MD (1) | MD3982960T2 (https=) |
| MX (1) | MX2021014557A (https=) |
| MY (1) | MY205687A (https=) |
| PH (1) | PH12021552966A1 (https=) |
| PL (1) | PL3982960T3 (https=) |
| PT (1) | PT3982960T (https=) |
| RS (1) | RS64412B1 (https=) |
| SG (1) | SG11202113304YA (https=) |
| SI (1) | SI3982960T1 (https=) |
| SM (1) | SMT202300261T1 (https=) |
| TW (1) | TW202112370A (https=) |
| UA (1) | UA129869C2 (https=) |
| WO (1) | WO2020249977A1 (https=) |
| ZA (1) | ZA202110685B (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201609607D0 (en) | 2016-06-01 | 2016-07-13 | Kalvista Pharmaceuticals Ltd | Polymorphs of N-(3-Fluoro-4-methoxypyridin-2-yl)methyl)-3-(methoxymethyl)-1-({4-((2-oxopy ridin-1-yl)methyl)phenyl}methyl)pyrazole-4-carboxamide and salts |
| GB201719881D0 (en) | 2017-11-29 | 2018-01-10 | Kalvista Pharmaceuticals Ltd | Solid forms of plasma kallikrein inhibitor and salts thereof |
| GB201910116D0 (en) * | 2019-07-15 | 2019-08-28 | Kalvista Pharmaceuticals Ltd | Treatments of hereditary angioedema |
| WO2021028645A1 (en) | 2019-08-09 | 2021-02-18 | Kalvista Pharmaceuticals Limited | Plasma kallikrein inhibitors |
| US20230381162A1 (en) * | 2020-10-23 | 2023-11-30 | Kalvista Pharmaceuticals Limited | Treatments of angioedema |
| JP2024505596A (ja) * | 2021-02-09 | 2024-02-06 | カルビスタ・ファーマシューティカルズ・リミテッド | 遺伝性血管性浮腫の治療 |
| US20250281397A1 (en) | 2022-04-27 | 2025-09-11 | Kalvista Pharmaceuticals Limited | Formulations of a plasma kallikrein inhibitor |
| CN116003386B (zh) * | 2022-11-20 | 2024-03-26 | 药康众拓(北京)医药科技有限公司 | 一种氘代n-苄基吡啶酮吡唑甲酰胺类化合物、药物组合物和用途 |
| WO2025172693A1 (en) | 2024-02-13 | 2025-08-21 | Kalvista Pharmaceuticals Limited | Oral sebetralstat for the treatment of an attack of hereditary angioedema |
| WO2025172692A1 (en) | 2024-02-13 | 2025-08-21 | Kalvista Pharmaceuticals Limited | Oral sebetralstat for the treatment of an attack of hereditary angioedema |
| WO2026003532A1 (en) | 2024-06-28 | 2026-01-02 | Kalvista Pharmaceuticals Limited | Sebetralstat for the treatment of anxiety associated with hereditary angioedema |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5187157A (en) | 1987-06-05 | 1993-02-16 | Du Pont Merck Pharmaceutical Company | Peptide boronic acid inhibitors of trypsin-like proteases |
| GB9019558D0 (en) | 1990-09-07 | 1990-10-24 | Szelke Michael | Enzyme inhibitors |
| SE9301911D0 (sv) | 1993-06-03 | 1993-06-03 | Ab Astra | New peptide derivatives |
| US5589467A (en) | 1993-09-17 | 1996-12-31 | Novo Nordisk A/S | 2,5',N6-trisubstituted adenosine derivatives |
| GB0205527D0 (en) | 2002-03-08 | 2002-04-24 | Ferring Bv | Inhibitors |
| US7429604B2 (en) | 2004-06-15 | 2008-09-30 | Bristol Myers Squibb Company | Six-membered heterocycles useful as serine protease inhibitors |
| JP5322935B2 (ja) | 2006-07-31 | 2013-10-23 | アクティベサイト ファーマシューティカルズ インコーポレイティッド | 血漿カリクレインの阻害薬 |
| DE102006050672A1 (de) | 2006-10-24 | 2008-04-30 | Curacyte Discovery Gmbh | Hemmstoffe des Plasmins und des Plasmakallikreins |
| JP2013121919A (ja) | 2010-03-25 | 2013-06-20 | Astellas Pharma Inc | 血漿カリクレイン阻害剤 |
| EP2590945B1 (en) | 2010-07-07 | 2014-04-30 | The Medicines Company (Leipzig) GmbH | Serine protease inhibitors |
| US20130210809A1 (en) | 2010-07-14 | 2013-08-15 | Christelle Boléa | Novel 2-amino-4-pyrazolyl-thiazole derivatives and their use as allosteric modulators of metabotropic glutamate receptors |
| US9290485B2 (en) | 2010-08-04 | 2016-03-22 | Novartis Ag | N-((6-amino-pyridin-3-yl)methyl)-heteroaryl-carboxamides |
| GB2494851A (en) | 2011-07-07 | 2013-03-27 | Kalvista Pharmaceuticals Ltd | Plasma kallikrein inhibitors |
| GB201300304D0 (en) | 2013-01-08 | 2013-02-20 | Kalvista Pharmaceuticals Ltd | Benzylamine derivatives |
| MY174018A (en) | 2013-05-23 | 2020-03-04 | Kalvista Pharmaceuticals Ltd | Heterocyclic derivates |
| EP2815749A1 (en) * | 2013-06-20 | 2014-12-24 | IP Gesellschaft für Management mbH | Solid form of 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione having specified X-ray diffraction pattern |
| EP2886107A1 (en) * | 2013-12-17 | 2015-06-24 | ObsEva S.A. | Oral formulations of pyrrolydine derivatives |
| GB201421083D0 (en) | 2014-11-27 | 2015-01-14 | Kalvista Pharmaceuticals Ltd | Enzyme inhibitors |
| GB201721515D0 (en) * | 2017-12-21 | 2018-02-07 | Kalvista Pharmaceuticals Ltd | Dosage forms comprising a plasma kallikrein inhibtor |
| GB201910116D0 (en) * | 2019-07-15 | 2019-08-28 | Kalvista Pharmaceuticals Ltd | Treatments of hereditary angioedema |
-
2019
- 2019-07-15 GB GBGB1910116.1A patent/GB201910116D0/en not_active Ceased
-
2020
- 2020-06-15 EP EP23181261.1A patent/EP4282474A3/en active Pending
- 2020-06-15 SM SM20230261T patent/SMT202300261T1/it unknown
- 2020-06-15 KR KR1020217043374A patent/KR102748728B1/ko active Active
- 2020-06-15 BR BR112021024664A patent/BR112021024664A2/pt not_active Application Discontinuation
- 2020-06-15 FI FIEP20734283.3T patent/FI3982960T3/fi active
- 2020-06-15 PH PH1/2021/552966A patent/PH12021552966A1/en unknown
- 2020-06-15 TW TW109120108A patent/TW202112370A/zh unknown
- 2020-06-15 MX MX2021014557A patent/MX2021014557A/es unknown
- 2020-06-15 CN CN202080043365.6A patent/CN114126612A/zh active Pending
- 2020-06-15 EP EP20734283.3A patent/EP3982960B1/en active Active
- 2020-06-15 UA UAA202106869A patent/UA129869C2/uk unknown
- 2020-06-15 ES ES20734283T patent/ES2956471T3/es active Active
- 2020-06-15 HU HUE20734283A patent/HUE063163T2/hu unknown
- 2020-06-15 US US17/617,439 patent/US20220218680A1/en active Pending
- 2020-06-15 MA MA56187A patent/MA56187B1/fr unknown
- 2020-06-15 SG SG11202113304YA patent/SG11202113304YA/en unknown
- 2020-06-15 LT LTEPPCT/GB2020/051439T patent/LT3982960T/lt unknown
- 2020-06-15 MD MDE20220440T patent/MD3982960T2/ro unknown
- 2020-06-15 CA CA3142218A patent/CA3142218A1/en active Pending
- 2020-06-15 JP JP2021571931A patent/JP7356518B2/ja active Active
- 2020-06-15 WO PCT/GB2020/051439 patent/WO2020249977A1/en not_active Ceased
- 2020-06-15 SI SI202030247T patent/SI3982960T1/sl unknown
- 2020-06-15 DK DK20734283.3T patent/DK3982960T3/da active
- 2020-06-15 PT PT207342833T patent/PT3982960T/pt unknown
- 2020-06-15 EA EA202193019A patent/EA202193019A1/ru unknown
- 2020-06-15 RS RS20230620A patent/RS64412B1/sr unknown
- 2020-06-15 HR HRP20230696TT patent/HRP20230696T1/hr unknown
- 2020-06-15 MY MYPI2021007320A patent/MY205687A/en unknown
- 2020-06-15 PL PL20734283.3T patent/PL3982960T3/pl unknown
- 2020-06-15 AU AU2020293614A patent/AU2020293614B2/en active Active
- 2020-06-16 AR ARP200101681A patent/AR119158A1/es unknown
-
2021
- 2021-12-02 IL IL288615A patent/IL288615A/en unknown
- 2021-12-06 CL CL2021003244A patent/CL2021003244A1/es unknown
- 2021-12-20 ZA ZA2021/10685A patent/ZA202110685B/en unknown
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2023
- 2023-03-06 CL CL2023000639A patent/CL2023000639A1/es unknown
- 2023-08-14 JP JP2023131860A patent/JP7688078B2/ja active Active
-
2025
- 2025-05-21 JP JP2025084646A patent/JP2025124716A/ja active Pending