JP2023139438A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2023139438A5 JP2023139438A5 JP2022044972A JP2022044972A JP2023139438A5 JP 2023139438 A5 JP2023139438 A5 JP 2023139438A5 JP 2022044972 A JP2022044972 A JP 2022044972A JP 2022044972 A JP2022044972 A JP 2022044972A JP 2023139438 A5 JP2023139438 A5 JP 2023139438A5
- Authority
- JP
- Japan
- Prior art keywords
- microparticles
- pqbp1
- mir
- suppression
- hsa
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022044972A JP7492757B2 (ja) | 2022-03-22 | 2022-03-22 | 遺伝子の発現制御剤、アルツハイマー病の予防薬または治療薬および認知症の改善方法 |
| CN202380027002.7A CN119031942A (zh) | 2022-03-22 | 2023-03-19 | 基因表达调控剂、阿尔茨海默症的预防药或治疗药和痴呆的改善方法 |
| US18/848,758 US20250195554A1 (en) | 2022-03-22 | 2023-03-19 | Gene expression regulator, agent for preventing or treating alzheimer's disease and method for improving dementia |
| PCT/JP2023/010775 WO2023182243A1 (ja) | 2022-03-22 | 2023-03-19 | 遺伝子の発現制御剤、アルツハイマー病の予防薬または治療薬および認知症の改善方法 |
| EP23774838.9A EP4497445A1 (en) | 2022-03-22 | 2023-03-19 | Gene expression regulator, prophylactic drug or therapeutic drug for alzheimer's disease, and method for improving dementia |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022044972A JP7492757B2 (ja) | 2022-03-22 | 2022-03-22 | 遺伝子の発現制御剤、アルツハイマー病の予防薬または治療薬および認知症の改善方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023139438A JP2023139438A (ja) | 2023-10-04 |
| JP2023139438A5 true JP2023139438A5 (https=) | 2023-11-14 |
| JP7492757B2 JP7492757B2 (ja) | 2024-05-30 |
Family
ID=88100891
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022044972A Active JP7492757B2 (ja) | 2022-03-22 | 2022-03-22 | 遺伝子の発現制御剤、アルツハイマー病の予防薬または治療薬および認知症の改善方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20250195554A1 (https=) |
| EP (1) | EP4497445A1 (https=) |
| JP (1) | JP7492757B2 (https=) |
| CN (1) | CN119031942A (https=) |
| WO (1) | WO2023182243A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPWO2025170079A1 (https=) * | 2024-02-09 | 2025-08-14 | ||
| CN118236389B (zh) * | 2024-05-28 | 2024-09-24 | 南京晖丽生物科技有限公司 | miR-3120在制备预防及治疗肿瘤及肿瘤恶液质的药物组合物中的应用 |
| CN119185350B (zh) * | 2024-08-15 | 2025-09-09 | 安徽农业大学 | 靶向lrp6的抑制剂在调节动物剩余采食量中的应用 |
| CN119193819B (zh) * | 2024-11-28 | 2025-05-13 | 苏州麦锐克生物科技有限公司 | 用于阿尔茨海默病诊断的多重miRNA标志物及试剂盒 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPWO2011118795A1 (ja) | 2010-03-26 | 2013-07-04 | 国立大学法人名古屋大学 | 損傷部治療用組成物 |
| JP2017184642A (ja) | 2016-04-01 | 2017-10-12 | 株式会社ヘルシーパス | 認知症マーカー、それを用いた認知症の評価方法、評価試薬および評価キット |
| JP2018023343A (ja) | 2016-08-12 | 2018-02-15 | 国立大学法人山口大学 | 細胞培養用培地、及び細胞培養方法 |
| IL264825B (en) | 2016-08-14 | 2022-08-01 | Univ Ramot | Mesenchymal cell-derived exosomes to treat neurological disorders |
| US12233092B2 (en) | 2018-04-10 | 2025-02-25 | Brainstorm Cell Therapeutics Ltd. | MSC-NTF specific exosomes and use thereof |
| AU2020299633B2 (en) * | 2019-07-02 | 2026-03-26 | Ohio State Innovation Foundation | Neurodegenerative disease therapies utilizing the skin-brain axis |
| US20210002650A1 (en) * | 2019-07-03 | 2021-01-07 | University Of Virginia Patent Foundation | Compositions and methods for treating alzheimer's disease |
-
2022
- 2022-03-22 JP JP2022044972A patent/JP7492757B2/ja active Active
-
2023
- 2023-03-19 EP EP23774838.9A patent/EP4497445A1/en active Pending
- 2023-03-19 CN CN202380027002.7A patent/CN119031942A/zh active Pending
- 2023-03-19 US US18/848,758 patent/US20250195554A1/en active Pending
- 2023-03-19 WO PCT/JP2023/010775 patent/WO2023182243A1/ja not_active Ceased
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2023139438A5 (https=) | ||
| Li et al. | The phase changes of M1/M2 phenotype of microglia/macrophage following oxygen-induced retinopathy in mice | |
| Vashi et al. | Treating Rett syndrome: from mouse models to human therapies | |
| Hu et al. | Genistein protects epilepsy-induced brain injury through regulating the JAK2/STAT3 and Keap1/Nrf2 signaling pathways in the developing rats | |
| Leszek et al. | Inflammatory mechanisms and oxidative stress as key factors responsible for progression of neurodegeneration: role of brain innate immune system | |
| Li et al. | The role of Sp1 and Sp3 in normal and cancer cell biology | |
| Gheorghe et al. | Silencing the cytoskeleton protein Iba1 (ionized calcium binding adapter protein 1) interferes with BV2 microglia functioning | |
| AU2019384547B2 (en) | Compositions and methods for increasing fetal hemoglobin and treating sickle cell disease | |
| JP2017158561A5 (https=) | ||
| US11331373B2 (en) | Combination therapy for treating disorders of the ear | |
| JP2010516290A5 (https=) | ||
| JP2019523648A5 (https=) | ||
| WO2020127532A3 (en) | Rna encoding a protein | |
| WO2020214809A3 (en) | Gene therapies for stargardt disease (abca4) | |
| Zheng et al. | Pivotal role of cerebral interleukin-23 during immunologic injury in delayed cerebral ischemia in mice | |
| Sun et al. | Peimine inhibits MCF-7 breast cancer cell growth by modulating inflammasome activation: critical roles of MAPK and NF-κB signaling | |
| JP2022548800A5 (https=) | ||
| JOP20250158A1 (ar) | بروتين ثلاثى النوع يستهدف trop2 لعلاج السرطان | |
| Fang et al. | Inhibition of the NLRP3 inflammasome attenuates spiral ganglion neuron degeneration in aminoglycoside-induced hearing loss | |
| JP2007504840A5 (https=) | ||
| AU2928199A (en) | Method for the treatment of diseases or disorders of the inner ear | |
| Ohnishi et al. | p53 targeting can enhance cancer therapy via radiation, heat and anti-cancer agents | |
| Bao et al. | Transcriptome profiling of the subventricular zone and dentate gyrus in an animal model of Parkinson's disease | |
| KR20240086713A (ko) | Gas5 억제제 및 smarca4 억제제를 유효성분으로 포함하는 간암 예방 또는 치료용 약학 조성물 | |
| CN101431993A (zh) | Dha和ara在制备用于调节基因表达的组合物中的用途 |