JP2023088944A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2023088944A5 JP2023088944A5 JP2023040600A JP2023040600A JP2023088944A5 JP 2023088944 A5 JP2023088944 A5 JP 2023088944A5 JP 2023040600 A JP2023040600 A JP 2023040600A JP 2023040600 A JP2023040600 A JP 2023040600A JP 2023088944 A5 JP2023088944 A5 JP 2023088944A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- subject
- csa
- dose
- plasma concentration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762527983P | 2017-06-30 | 2017-06-30 | |
| US62/527,983 | 2017-06-30 | ||
| PCT/US2018/040181 WO2019006235A1 (en) | 2017-06-30 | 2018-06-29 | METHODS OF TREATING CARDIAC INSUFFICIENCY WITH CARDIAC SARCOMER ACTIVATORS |
| JP2019570045A JP2020526483A (ja) | 2017-06-30 | 2018-06-29 | 心筋節活性化剤で心不全を治療する方法 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019570045A Division JP2020526483A (ja) | 2017-06-30 | 2018-06-29 | 心筋節活性化剤で心不全を治療する方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023088944A JP2023088944A (ja) | 2023-06-27 |
| JP2023088944A5 true JP2023088944A5 (zh) | 2023-09-01 |
Family
ID=63013097
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019570045A Pending JP2020526483A (ja) | 2017-06-30 | 2018-06-29 | 心筋節活性化剤で心不全を治療する方法 |
| JP2023040600A Pending JP2023088944A (ja) | 2017-06-30 | 2023-03-15 | 心筋節活性化剤で心不全を治療する方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019570045A Pending JP2020526483A (ja) | 2017-06-30 | 2018-06-29 | 心筋節活性化剤で心不全を治療する方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US11576910B2 (zh) |
| EP (1) | EP3645002A1 (zh) |
| JP (2) | JP2020526483A (zh) |
| CN (1) | CN110996953A (zh) |
| AU (2) | AU2018290983B2 (zh) |
| BR (1) | BR112019028046A2 (zh) |
| CA (1) | CA3068588A1 (zh) |
| MA (1) | MA49508A (zh) |
| MX (2) | MX2020000190A (zh) |
| WO (1) | WO2019006235A1 (zh) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA031185B1 (ru) | 2013-03-14 | 2018-11-30 | Эмджен Инк. | Гетероциклические соединения и способы их применения |
| SI3645518T1 (sl) | 2017-06-30 | 2021-11-30 | Amgen Inc. | Sinteza omekamtiv mekarbila |
| MX2020000190A (es) | 2017-06-30 | 2020-07-22 | Amgen Inc | Métodos para tratar la insuficiencia cardíaca con activadores de sarcómero cardíaco. |
| AU2019321573A1 (en) | 2018-08-17 | 2021-03-04 | Amgen Inc. | Salts and crystal forms of omecamtiv mecarbil |
| CA3200673A1 (en) * | 2020-11-12 | 2022-05-19 | Amgen Inc. | Methods of treating heart failure by administering omecamtiv mecarbil |
| CA3212491A1 (en) | 2021-03-10 | 2022-09-15 | Sebastien Caille | Synthesis of omecamtiv mecarbil |
| WO2023164452A2 (en) * | 2022-02-22 | 2023-08-31 | Yale University | Methods of treating, ameliorating, or preventing heart failure, and methods of promoting heart muscle growth |
| WO2024081611A1 (en) * | 2022-10-11 | 2024-04-18 | Cytokinetics, Incorporated | Methods for treating heart failure by administering cardiac sarcomere activators |
| US11986474B1 (en) | 2023-06-27 | 2024-05-21 | Cytokinetics, Incorporated | Methods for treating heart failure by administering cardiac sarcomere activators |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4450150A (en) | 1973-05-17 | 1984-05-22 | Arthur D. Little, Inc. | Biodegradable, implantable drug delivery depots, and method for preparing and using the same |
| AU2546399A (en) | 1998-02-10 | 1999-08-30 | Yoshitomi Pharmaceutical Industries, Ltd. | Preparations with controlled release |
| GB2344287A (en) | 1998-12-03 | 2000-06-07 | Ferring Bv | Controlled release pharmaceutical formulation |
| EP1551505B1 (en) | 2002-10-04 | 2010-02-24 | Microchips, Inc. | Medical device for controlled drug delivery and cardiac monitoring and/or stimulation |
| EP2862859B1 (en) | 2004-06-17 | 2018-07-25 | Cytokinetics, Inc. | Compounds, compositions and methods |
| AR058347A1 (es) | 2005-12-15 | 2008-01-30 | Cytokinetics Inc | Entidades quimias composiciones y metodos |
| JP2009537530A (ja) | 2006-05-15 | 2009-10-29 | ウィスコンシン・アルムニ・リサーチ・ファウンデーション | １α，２５−ジヒドロキシビタミンＤ３の肺送達および副甲状腺ホルモンまたはカルシトニンの同時投与 |
| FR2902092B1 (fr) | 2006-06-07 | 2008-09-05 | Sapelem Soc Par Actions Simpli | Appareil de manutention de charge |
| CN101657190B (zh) | 2007-04-19 | 2013-09-11 | 东亚制药株式会社 | 一种适用于对葡萄糖控制肽进行控释的可生物降解的微球组合物及其制剂 |
| EA031185B1 (ru) | 2013-03-14 | 2018-11-30 | Эмджен Инк. | Гетероциклические соединения и способы их применения |
| JP6634368B2 (ja) * | 2013-03-14 | 2020-01-22 | アムジエン・インコーポレーテツド | 複素環式化合物及びそれらの使用 |
| US20180022710A1 (en) | 2015-01-29 | 2018-01-25 | Signal Pharmaceuticals, Llc | Isotopologues of 2-(tert-butylamino)-4-((1r,3r,4r)-3-hydroxy-4-methylcyclohexylamino)-pyrimidine-5-carboxamide |
| AU2016282985B2 (en) | 2015-06-26 | 2021-07-29 | Amgen Inc. | Combination therapy of cardiac myosin activator and sinus node if current inhibitor |
| SI3645518T1 (sl) | 2017-06-30 | 2021-11-30 | Amgen Inc. | Sinteza omekamtiv mekarbila |
| MX2020000190A (es) | 2017-06-30 | 2020-07-22 | Amgen Inc | Métodos para tratar la insuficiencia cardíaca con activadores de sarcómero cardíaco. |
| LT3594199T (lt) | 2018-07-09 | 2020-11-10 | F.I.S.- Fabbrica Italiana Sintetici S.P.A. | Kristalinis 2-fluor-3-nitroluenas ir jo paruošimo būdas |
| WO2020014406A1 (en) | 2018-07-12 | 2020-01-16 | Assia Chemical Industries Ltd. | Solid state forms of omecamtiv mecarbil & omecamtiv mecarbil dihcl |
| AU2019321573A1 (en) | 2018-08-17 | 2021-03-04 | Amgen Inc. | Salts and crystal forms of omecamtiv mecarbil |
| WO2020131574A1 (en) | 2018-12-18 | 2020-06-25 | Amgen Inc. | Method of reducing aromatic nitro compounds |
| US20220340542A1 (en) | 2019-09-19 | 2022-10-27 | Synthon B.V. | Salts of omecamtiv mecarbil and solid forms thereof |
| WO2021053175A1 (en) | 2019-09-19 | 2021-03-25 | Synthon B.V. | Salts of omecamtiv mecarbil and solid forms thereof |
| US20220411374A1 (en) | 2019-10-09 | 2022-12-29 | Dr. Reddy's Laboratories Limited | Alternate processes for the preparation of omecamtiv mecarbil |
| EP4041198A4 (en) | 2019-10-09 | 2023-08-16 | Dr. Reddy's Laboratories Limited | SOLID FORMS OF OMECAMTIV MECARBIL DIHYDROCHLORIDE AND PROCESS THEREOF |
| WO2021136477A1 (zh) | 2020-01-03 | 2021-07-08 | 苏州科睿思制药有限公司 | 化合物i二盐酸盐的共晶及其制备方法和用途 |
| CN115279349A (zh) | 2020-02-10 | 2022-11-01 | 安进股份有限公司 | 奥美卡替莫卡必尔片剂 |
| CA3200673A1 (en) | 2020-11-12 | 2022-05-19 | Amgen Inc. | Methods of treating heart failure by administering omecamtiv mecarbil |
| CA3212491A1 (en) | 2021-03-10 | 2022-09-15 | Sebastien Caille | Synthesis of omecamtiv mecarbil |
| WO2023205291A2 (en) | 2022-04-21 | 2023-10-26 | The Board Of Regents Of The University Of Oklahoma | Targeting myocardial tissue for delivery of therapeutic and imaging agents |
-
2018
- 2018-06-29 MX MX2020000190A patent/MX2020000190A/es unknown
- 2018-06-29 AU AU2018290983A patent/AU2018290983B2/en active Active
- 2018-06-29 MA MA049508A patent/MA49508A/fr unknown
- 2018-06-29 CA CA3068588A patent/CA3068588A1/en active Pending
- 2018-06-29 BR BR112019028046-4A patent/BR112019028046A2/pt active Search and Examination
- 2018-06-29 EP EP18745732.0A patent/EP3645002A1/en active Pending
- 2018-06-29 US US16/625,958 patent/US11576910B2/en active Active
- 2018-06-29 CN CN201880053343.0A patent/CN110996953A/zh active Pending
- 2018-06-29 WO PCT/US2018/040181 patent/WO2019006235A1/en active Application Filing
- 2018-06-29 JP JP2019570045A patent/JP2020526483A/ja active Pending
-
2020
- 2020-01-08 MX MX2022015115A patent/MX2022015115A/es unknown
-
2023
- 2023-01-17 US US18/155,483 patent/US20230149394A1/en active Pending
- 2023-03-15 JP JP2023040600A patent/JP2023088944A/ja active Pending
- 2023-05-05 US US18/313,267 patent/US11931358B2/en active Active
-
2024
- 2024-02-15 AU AU2024200991A patent/AU2024200991A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2023088944A5 (zh) | ||
| KR101718639B1 (ko) | 선별적 ｓ1ｐ₁ 수용체 작동약에 대한 투약 섭생 | |
| US3795739A (en) | Treatment of parkinson disease | |
| JP2020529996A5 (zh) | ||
| JP2020526483A5 (zh) | ||
| JP2009513713A5 (zh) | ||
| JP2007506752A (ja) | 肺動脈高血圧症を治療するための併用療法におけるイロプロスト | |
| Mooss et al. | Efficacy and tolerance of high-dose intravenous amiodarone for recurrent, refractory ventricular tachycardia | |
| JP2024019691A (ja) | 肺動脈性高血圧症および他疾患に関連する肺動脈性肺高血圧症の治療法 | |
| EP2326324A1 (en) | Use of dronedarone for the preparation of a medicament for the prevention of stroke or transient ischemic attack | |
| JP2020529440A5 (zh) | ||
| JP2022514537A (ja) | 急性心房細動の処置のためのサルカルディン投与 | |
| JP2011518147A (ja) | 血中カリウム濃度を調節する薬剤を調製するためのドロネダロンまたは医薬的に許容されるこの塩の使用 | |
| US20110166221A1 (en) | Use of dronedarone for the preparation of a medicament for use in the prevention of cardioversion | |
| JP3084059B2 (ja) | 甲状腺ホルモン心臓治療 | |
| JP2012525358A5 (zh) | ||
| KR20120089623A (ko) | 정맥내 투여용 이부프로펜을 이용한 환자의 치료 | |
| WO2017148129A1 (zh) | 一种用于治疗恶病质的药物组合物及其应用 | |
| JP2019535830A5 (zh) | ||
| JPWO2019236757A5 (zh) | ||
| EP2988750B1 (en) | Use of landiolol hydrochloride in the long-term treatment of tachyarrhythmias | |
| JP2019178177A5 (zh) | ||
| JP6420923B1 (ja) | 医薬 | |
| US20190381034A1 (en) | Pharmaceutical composition and method for acute on chronic liver failure and related liver diseases | |
| WO2013051330A1 (ja) | ビダラビンによる心房細動治療 |